Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Preventing autoimmune disease after a viral infection

Researchers used mice to study regulatory mechanisms in the immune system that prevent autoimmune disease. Using an influenza infection model in mice, they have found that a particular population of immune cells developed during the later stages of the immune response to the influenza infection. These cells, called T follicular regulatory cells, subsequently prevented the generation of self-reactive antibody responses. At the same time, they did not affect the influenza-specific immune reaction. (Mehr in: Cancer News — ScienceDaily)

Researchers discover the central regulatory mechanism for spike architecture in barley

An international team of researchers under the leadership of Dr. habil. Thorsten Schnurbusch, head of the independent HEISENBERG-Research Group „Plant Architecture“ at the Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), and his fellow Dr. Helmy Youssef published their findings about molecular and hormonal mechanism essential for the regulation of inflorescence and shoot development in barley in the renowned scientific journal ‘Nature Genetics’. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

‚Key‘ to recognizing, immunizing herpes/common cold

Prior to this study, it was known that interferon regulatory factor-3 (IRF-3), a protein coding gene, contributed to a first line of defense against viral infection by triggering antiviral activity. However the activation of IRF-3 following infection was not fully understood. The study found that an interaction with the protein S6K1 and the signaling adaptor STING is a fundamental regulatory mechanism for IRF3 and, thus, helps trigger antiviral responses. (Mehr in: Cancer News — ScienceDaily)

Master switch for brain development

Scientists at the Institute of Molecular Biology (IMB) in Mainz have unraveled a complex regulatory mechanism that explains how a single gene can drive the formation of brain cells. The research, published in The EMBO Journal, is an important step towards a better understanding of how the brain develops. It also harbors potential for regenerative medicine. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Scientists in Cologne identify important lysine-acetylation regulatory mechanisms for Ran protein.

The team of scientists led by Dr. Michael Lammers at CECAD, the Cluster of Excellence at the University of Cologne, has discovered that the essential cellular protein Ran is fundamentally regulated by lysine acetylation. Ran belongs to the family of Ras proteins, which regulate fundamental cellular processes such as cell differentiation, cell division, and intracellular transport. Mutations in Ras-related proteins are involved in the development of various types of cancer including colorectal cancer, lung cancer, and lymphomas. Mechanisms that can switch off the functions of Ran protein are therefore of particular therapeutic interest. (Mehr in: Pressemitteilungen – idw – Informationsdienst […]

When genes are expressed in reverse: regulatory mechanism of antisense DNA discovered

Researchers have uncovered new clues to help understand the functions of antisense DNA and its alterations in cancer. Antisense transcripts are DNA sequences that ‚rebel,‘ DNA that are activated in reverse: from right to left. Very little of the function of these is known, but new work provides new clues and mechanisms to understand their functions and their alterations in cancer. (Mehr in: Cancer News — ScienceDaily)

Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci

3D-SIM-based DAPI intensity classification in the Barr body versus the entire nucleus of C2C12 cells. (A) Mid z-section of a DAPI-stained nucleus. The area below the dashed line illustrates the resolution level obtained by wide-field deconvolution microscopy, for comparison. Inset magnifications show the non-uniformly compacted structure of the Barr body resolvable with 3D-SIM (1) and an arbitrary autosomal region with CDCs (2). Scale bars: 5 μm, insets 1 μm. (B) X chromosome-specific painting (green) of Xi (left) and Xa territories (right) of the same nucleus in different z-sections. Note the high convergence between the painted Xi and the DAPI […]

Cancer’s ability to ‚hijack‘ regulatory mechanism increases metastasis

When skyscrapers go up, contractors rely on an infrastructure of steel beams and braces. Some cancers grow the same way, using a biological matrix from which the tumor can thrive and spread. (Mehr in: Cancer News — ScienceDaily)

Cancer news

Creation of synthetic horsepox virus could lead to more effective smallpox vaccine

19. Jan. 2018

Researchers created a new synthetic virus that could lead to the development of a more effective vaccine against smallpox. The discovery demonstrates how techniques based on the use of synthetic DNA can be used to advance public health measures. (Mehr in: Cancer News — ScienceDaily)

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Factor that doubles the risk of death from breast cancer identified

19. Jan. 2018

Researchers have discovered that the risk of death from breast cancer is twice as high for patients with high heterogeneity of the estrogen receptor within the same tumor as compared to patients with low heterogeneity. The study shows that the higher risk of death is independent of other known tumor markers and also holds true for Luminal A breast cancer. (Mehr in: Cancer News — ScienceDaily)

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Structure of herpes virus linked to Kaposi’s sarcoma

19. Jan. 2018

Scientists have shown in the laboratory that an inhibitor can be developed to break down the herpes virus. Kaposi’s sarcoma-associated herpes virus, or KSHV, is one of two viruses known to cause cancer in humans. (Mehr in: Cancer News — ScienceDaily)

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Why animals diversified on Earth: Cancer research provides clues

18. Jan. 2018

Can tumors teach us about animal evolution on Earth? Researchers believe so and now present a novel hypothesis of why animal diversity increased dramatically on Earth about half a billion years ago. A biological innovation may have been key. (Mehr in: Cancer News — ScienceDaily)

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New method to stop cells dividing could help fight cancer

18. Jan. 2018

Researchers have used a new strategy to shut down specific enzymes to stop cells from dividing. The method can be used as a strategy to fight cancer. (Mehr in: Cancer News — ScienceDaily)

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Can mice really mirror humans when it comes to cancer?

18. Jan. 2018

A new study is helping to answer a pressing question among scientists of just how close mice are to people when it comes to researching cancer. The findings reveal how mice can actually mimic human breast cancer tissue and its genes, even more so than previously thought, as well as other cancers including lung, oral and esophagus. (Mehr in: Cancer News — ScienceDaily)

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How cancer metastasis happens: Researchers reveal a key mechanism

18. Jan. 2018

Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to new research. (Mehr in: Cancer News — ScienceDaily)

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Two new breast cancer genes emerge from lynch syndrome gene study

18. Jan. 2018

Researchers have identified two new breast cancer genes that also cause Lynch syndrome. (Mehr in: Cancer News — ScienceDaily)

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Single blood test screens for eight cancer types

18. Jan. 2018

Researchers have developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer. (Mehr in: Cancer News — ScienceDaily)

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A centuries-old math equation used to solve a modern-day genetics challenge

18. Jan. 2018

Researchers developed a new mathematical tool to validate and improve methods used by medical professionals to interpret results from clinical genetic tests. (Mehr in: Cancer News — ScienceDaily)

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Distorted view amongst smokers of when deadly damage caused by smoking will occur

18. Jan. 2018

Smokers have a distorted perception on when the onset of smoking-related conditions will occur, according to a new study. (Mehr in: Cancer News — ScienceDaily)

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New way to target the growth of breast cancer cells

17. Jan. 2018

Researchers have found a new way of halting the growth of breast cancer cells. The researchers explored a new way to starve cancer cells from their molecular energy source. They hope that their discoveries can be further developed into a new way of treating breast cancer, and possibly other types of cancer. (Mehr in: Cancer News — ScienceDaily)

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DIPG tumor patterns offer new insight on survival

17. Jan. 2018

A small subset of patients with tumors that bear mutations in a gene in the basic packaging of DNA (known as histone mutations) may have better outcomes than others, suggests new research. (Mehr in: Cancer News — ScienceDaily)

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Modular gene enhancer promotes leukemia and regulates effectiveness of chemotherapy

17. Jan. 2018

Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in this process, and is also known to play a role in cancer. Scientists have now found that just how big a role Myc plays is determined by a distant section of DNA that contains a cluster of gene enhancers. (Mehr in: Cancer News — ScienceDaily)

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Scientists zoom in to watch DNA code being read

17. Jan. 2018

Scientists have unveiled incredible images of how the DNA code is read and interpreted — revealing new detail about one of the fundamental processes of life. (Mehr in: Cancer News — ScienceDaily)

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Secrets of longevity protein revealed in new study

17. Jan. 2018

Named after the Greek goddess who spun the thread of life, Klotho proteins play an important role in the regulation of longevity and metabolism. In a recent study, researchers revealed the three-dimensional structure of one of these proteins, beta-Klotho, illuminating its intricate mechanism and therapeutic potential. (Mehr in: Cancer News — ScienceDaily)

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Patient-derived organoids may help personalize the treatment of gastrointestinal cancers

17. Jan. 2018

A new review highlights the potential of 3-D organoid models derived from patient cells to help personalize therapy for individuals with gastrointestinal cancers. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

7 Jahre frühe Nutzenbewertung nach AMNOG – Verfahren und Ergebnisse

12. Jan. 2018

Am Donnerstag, 25. Januar 2018 referiert die Leiterin des Bonner Instituts für evidenzbasierte Positionierung im Gesundheitswesen, Prof. Dr. Eva Susanne Dietrich, von 18:00 bis 19:30 Uhr über die verschiedenen Perspektiven des Arzneimittelmarktneuordnungsgesetzes. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Aktuelle Höhepunkte und Perspektiven der astronautischen und robotischen Raumfahrt in Europa

01. Jan. 2018

Öffentlicher Abendvortrag des NAWI e.V. +++ Referent: Astronaut Dr. Thomas Reiter, European Space Agency (ESA), Darmstadt (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Advances in Chemical Biology

01. Jan. 2018

Understanding and manipulating molecular biological processes including the function and interaction of proteins is the key challenge in chemical biology. The two-day conference „Advances in Chemical Biology“ brings you the latest from science and research. A special focus this year lies on research in Scandinavia. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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12. Jahrestagung der Deutschen Wirbelsäulengesellschaft (DWG)

20. Nov. 2017

Der diesjährige Schwerpunkt des Kongresses liegt auf den Themen Trauma und Tumor in der Wirbelsäulenchirurgie. Wichtige wissenschaftliche Beiträge zu Tumorerkrankungen, degenerativen Erkrankungen, entzündlichen und metabolischen Erkrankungen, Verletzungen und Deformitäten aber auch zu innovativen Techniken erwarten die Besucherinnen und Besucher. Dabei steht ein fächerübergreifender Ansatz im Vordergrund, denn auch auf dem Gebiet der Wirbelsäulenheilkunde gilt es, Bewährtes zu erhalten und gleichzeitig neuen Behandlungsmethoden gegenüber offen zu sein. Dass die Deutsche Wirbelsäulengesellschaft diesen Anspruch ernst nimmt, zeigt auch die Zentren-Zertifizierung, die in diesem Jahr gestartet wurde. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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6. Morbi-RSA Symposium

01. Nov. 2017

Eigentlich soll der morbiditätsorientierte Risikostrukturausgleich – kurz: Morbi-RSA – den Finanzausgleich zwischen den gesetzlichen Krankenversicherungen regeln. Fakt ist: Die Kassen haben nach wie vor die Möglichkeit, ärztliche Diagnosen zu beeinflussen, um so höhere Zuwendungen aus dem Gesundheitsfonds zu erreichen. Das geht aus einem Gutachten des Berliner IGES Instituts hervor – und liefert jede Menge Zündstoff für das 6. Morbi-RSA Symposium am 20. November 2017 in Essen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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20. Gesundheitspolitisches Kolloquium

01. Nov. 2017

Wer übernimmt die Verantwortung in der Notfallversorgung? 20. Gesundheitspolitisches Kolloquium an der Frankfurt UAS diskutiert Optionen der Notfallversorgung in Hessen (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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20. Deutsche Mukoviszidose Tagung

01. Nov. 2017

Biomarker im klinischen Alltag, Problemkeime jenseits des Pseudomonas, die Bedeutung von Physiotherapie in der Mukoviszidose-Behandlung – dies sind nur einige Beispiele für das breite Themenspektrum der Deutschen Mukoviszidose Tagung, die vom 16. bis 18. November 2017 in Würzburg stattfindet. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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