Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

[ read more ]

Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

[ read more ]

Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

[ read more ]

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

[ read more ]

Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

[ read more ]

Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

[ read more ]

About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

[ read more ]

Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

[ read more ]

A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

[ read more ]

A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

[ read more ]

Rhythm of DNA replication exploited to kill cancer cells

Human cells divide and create new cells throughout life. In this process, a steady — even rhythmic — supply of DNA building blocks is needed to create new DNA. Now researchers have shown exactly how human cells regulate this process so it does not fail and cause illness. The researchers also show how they can manipulate the rhythm and suggest how this can be used in the future to kill cancer cells. (Mehr in: Cancer News — ScienceDaily)

The ‚DNA corrector‘ is more efficient in the most important regions of the genome

Error surveillance and repair mechanisms during DNA replication do not show the same competence in all regions of the human genome. Scientists have discovered that the mechanism that repairs errors in DNA is more efficient in the regions of genes that hold information for the production of proteins. (Mehr in: Cancer News — ScienceDaily)

Problems with DNA replication can cause epigenetic changes that may be inherited for several generations

Scientists reveal that a fault in the process that copies DNA during cell division can cause epigenetic changes that may be inherited for up-to five generations. They also identified the cause of these epigenetic changes, which is related to the loss of a molecular mechanism in charge of silencing genes. Their results will change the way we think about the impact of replication stress in cancer and during embryonic development, as well as its inter-generational inheritance. (Mehr in: Cancer News — ScienceDaily)

Squeezing life from DNA’s double helix

DNA replication begins when the double helix, caught in a vice of proteins, melts, scientists have discovered. (Mehr in: Cancer News — ScienceDaily)

Structure of key DNA replication protein solved

A research team has solved the three-dimensional structure of a key protein that helps damaged cellular DNA repair itself. Investigators say that knowing the chemical structure of the protein will likely help drug designers build novel anti-cancer agents. (Mehr in: Cancer News — ScienceDaily)

DNA Replication – Take a break

Before a cell divides, it must first handle a large-scale project: Its entire genetic material has to be duplicated so that each of the two daughter cells is equipped with a full copy after cell division. As errors in this DNA replication could lead to the death of the cell, the process is rigorously controlled. It takes place in two phases. Researchers at the Max Planck Institute of Biochemistry in Martinsried have now revealed in the journal Cell Reports that these two phases are strictly separated from one another by breaks, thereby preventing errors in the DNA replication. (Mehr in: […]

Enzyme with high potential for new cancer treatment identified

A team of researchers has identified an enzyme that separates DNA replication from repair. This discovery could be of tremendous significance in the treatment of tumors. (Mehr in: Cancer News — ScienceDaily)

Chromosomes: the importance of keeping the balance

The genetic material of cancer cells is unstable. For example, the number of chromosomes, which are the individual elements of packed DNA, is changed in so called aneuploidies. This imbalance in chromosomes, which often occurs early in tumor development, leads to cell stress and promotes disease. How this can happen is now shown by the discovery of a research team led by Zuzana Storchová at the Max Planck Institute of Biochemistry in Martinsried, reported in a groundbreaking study published in Nature Communications. An imbalance in an enzyme called MCM2-7 that is essential for DNA replication is likely to be responsible […]

Researchers connect haywire protein to breast cancer, leukemia

The cause of some cancers, including breast cancer and leukemia, is better understood, thanks to recent research. In the new study, the researchers found that too much of a key protein, called cyclin E, slows down DNA replication and introduces potentially harmful cancer-linked mutations when cells divide. (Mehr in: Cancer News — ScienceDaily)

A global assessment of cancer genomic alterations in epigenetic mechanisms

Muhammad A Shah, Emily L Denton, Cheryl H Arrowsmith, Mathieu Lupien and Matthieu Schapira

Abstract Background

The notion that epigenetic mechanisms may be central to cancer initiation and progression is supported by recent next-generation sequencing efforts revealing that genes involved in chromatin-mediated signaling are recurrently mutated in cancer patients.

Results

Here, we analyze mutational and transcriptional profiles from TCGA and the ICGC across a collection 441 chromatin factors and histones. Chromatin factors essential for rapid replication are frequently overexpressed, and those that maintain genome stability frequently mutated. We identify novel mutation hotspots such as K36M in histone H3.1, and uncover […]

Cancer news

Embryonic mammary gland stem cells identified

22. Mai. 2018

Scientists have identified the mechanisms that regulate mammary gland development. Using a combination of lineage tracing, molecular profiling, single cell sequencing and functional experiments, they have demonstrated that mammary gland initially develops from multipotent progenitors during the early steps of embryonic mammary gland morphogenesis whereas postnatal mammary gland development is mediated by lineage-restricted stem cells. (Mehr in: Cancer News — ScienceDaily)

- Read more

New data changes the way scientists explain how cancer tumors develop

21. Mai. 2018

A collaborative research team has uncovered new information that more accurately explains how cancerous tumors grow within the body. This study is currently available in Nature Genetics. (Mehr in: Cancer News — ScienceDaily)

- Read more

Deep space radiation treatment reboots brain’s immune system

21. Mai. 2018

NASA and private company SpaceX plan to send humans to Mars within the next 15 years — but need to figure out how to protect astronauts from the dangerous cosmic radiation of deep space. Now neuroscientists have identified a potential treatment for the brain damage caused by cosmic rays — a drug that prevents memory impairment in mice exposed to simulated space radiation. (Mehr in: Cancer News — ScienceDaily)

- Read more

Are humans causing cancer in wild animals?

21. Mai. 2018

As humans, we know that some of our activities can cause cancer to develop in our bodies. Smoking, poor diets, pollution, chemicals used as additives in food and personal hygiene products, and even too much sun can contribute to an increased risk of cancer. But, are human activities also causing cancer in wild animals? Researchers think so and are urgently calling for research into this topic. (Mehr in: Cancer News — ScienceDaily)

- Read more

Scientist reveals likely cause of childhood leukemia

21. Mai. 2018

A major new analysis reveals for the first time the likely cause of most cases of childhood leukemia, following more than a century of controversy about its origins. (Mehr in: Cancer News — ScienceDaily)

- Read more

Fewer men are being screened, diagnosed, and treated for prostate cancer

21. Mai. 2018

A new study reveals declines in prostate cancer screening and diagnoses in the United States in recent years, as well as decreases in the use of definitive treatments in men who have been diagnosed. (Mehr in: Cancer News — ScienceDaily)

- Read more

MR spectroscopy imaging reveals effects of targeted treatment of mutant IDH1 gliomas

18. Mai. 2018

Using a novel imaging method, a research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas. (Mehr in: Cancer News — ScienceDaily)

- Read more

A way to prevent pancreatic cancer from spreading post-surgery?

17. Mai. 2018

New research suggests a strategy for lowering the odds of metastasis following successful pancreatic cancer surgery: The post-operative period, suggests a researcher, ‚offers a window during which efforts might be made to keep cortisol levels down and T cells strong so the patient’s own immune system can kill the cancer cells that have made their way to other parts of the body but until this point have been dormant.‘ (Mehr in: Cancer News — ScienceDaily)

- Read more

Immune cell provides cradle for mammary stem cells

17. Mai. 2018

Researchers have made new discoveries about how an immune cell known as the macrophage, which normally fights infection by swallowing foreign invaders, nurtures mammary gland stem cells through a chemical signaling molecule. The study may provide important clues about the roles of macrophages in breast cancer progression. (Mehr in: Cancer News — ScienceDaily)

- Read more

Single surface protein boosts multiple oncogenic pathways in acute myeloid leukemia

17. Mai. 2018

Researchers have discovered that a signaling protein elevated in patients with acute myeloid leukemia (AML) plays a much wider role in the disease than previously thought. The study raises hopes that current efforts to target this signaling protein could be a successful strategy to treat AML and other blood cancers. (Mehr in: Cancer News — ScienceDaily)

- Read more

La Trobe’s infection-busting discovery

17. Mai. 2018

Scientists have shown a protein found in a tobacco plant has the potential to fight life-threatening infectious diseases. (Mehr in: Cancer News — ScienceDaily)

- Read more

Individualized ovarian, brain cancer therapies

16. Mai. 2018

Researchers have discovered that a molecular communication pathway — thought to be defective in cancer — is a key player in determining the effectiveness of measles virus oncolytic cancer treatment in ovarian and aggressive brain cancers. This discovery enabled researchers to develop an algorithm to predict treatment effectiveness in individual patients. (Mehr in: Cancer News — ScienceDaily)

- Read more

Diagnosing breast cancer with an imaging pill

16. Mai. 2018

For women, mammograms are a sometimes uncomfortable, but necessary, annual ritual. But this procedure doesn’t always provide accurate results, and it exposes women to X-rays. In a new study, scientists report that they have developed a non-invasive ‚disease screening pill‘ that can make cancerous tumors light up when exposed to near-infrared light in mice without using radiation. (Mehr in: Cancer News — ScienceDaily)

- Read more

Cell type switch helps colon cancer evade treatment, study suggests

16. Mai. 2018

Researchers have discovered that colon cancers are often resistant to existing drug treatments because they are composed of two different cell types that can replace each other when one cell type is killed. The study suggests that combination therapies targeting both cell types at once may be more effective at treating colorectal cancer, the third highest cause of cancer-related death in the United States. (Mehr in: Cancer News — ScienceDaily)

- Read more

Taming random gene changes as our bodies start to form

15. Mai. 2018

Scientists exploring how to tame random gene fluctuations as the embryos that become our bodies start to form have identified a control switch in the vertebrate segmentation clock of developing zebrafish. The researchers report their findings could uncover methods for modulating genetic signals to prevent birth defects or cancers rooted at the earliest stages of development. (Mehr in: Cancer News — ScienceDaily)

- Read more

Different diseases elicit distinct sets of exhausted T cells

15. Mai. 2018

The battle between the human immune system and long-term, persisting infections and other chronic diseases such as cancer results in a prolonged stalemate. Over time battle-weary T cells become exhausted, giving germs or tumors an edge. Using data from multiple molecular databases, researchers have found nine distinct types of exhausted T cells, which could have implications for fighting chronic infections, autoimmunity, and cancer. (Mehr in: Cancer News — ScienceDaily)

- Read more

First clues to the causes of multiple sclerosis

15. Mai. 2018

There is still no cure for multiple sclerosis, with current treatments largely based on managing symptoms, especially accelerating recovery phases following a relapse and reducing the number and severity of relapses. Researchers have now identified a DNA-binding factor called TOX that might play a role in triggering multiple sclerosis. They found that TOX license immune cells to cause autoimmune tissue destruction in the brain. (Mehr in: Cancer News — ScienceDaily)

- Read more

Veranstaltungen

102. Jahrestagung der Deutschen Gesellschaft für Pathologie e.V.

23. Mai. 2018

Vom 24. bis 26. Mai 2018 tagt die Deutsche Gesellschaft für Pathologie e.V. (DGP) in Berlin zum 102. Mal. Auch in diesem Jahr sind die Beiträge auf der Tagung durch die bahnbrechenden Entwicklungen im Bereich der Molekularpathologie und den Einzug digitaler Techniken in den Arbeitsalltag der Pathologinnen und Pathologen geprägt. Dieser Trend hat auch im besonderen Maße Einfluss auf die Schwerpunkte des Kongresses: Tumorevolution und Tumorheterogenität sowie seltene Erkrankungen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

Das Babel-Projekt I – Epistemische Funktionen von Metaphern im wissenschaftlichen Erkenntnisprozess

02. Mai. 2018

Unsere Wahrnehmung der Welt und der wissenschaftliche Zugang zu ihrer kausalen Struktur sind wesentlich mit dem Gebrauch von Sprache – insbesondere Metaphern – verbunden. Metaphern erfüllen epistemische Funktionen, indem sie durch die Anlehnung an einen bekannten Quellbereich eine speziell geartete Vorstellung eines neuen, abstrakteren Konzeptes (Zielbereich) vermitteln. Sie sind somit auch für die Neukonstruktion und Artikulation von Theorien und Begriffen bedeutsam. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

89. Jahresversammlung der DGHNO KHC „Forschung heute – Zukunft morgen“

02. Mai. 2018

89. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V. (DGHNO KHC) „Forschung heute – Zukunft morgen“ Termin: Mittwoch, 9. Mai bis Samstag 12. Mai 2018 Ort: Musik- und Kongresshalle (MuK), Willy-Brandt-Allee 10, D-23554 Lübeck (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

7. Jahrestreffen der Seniorexperten Chemie

02. Mai. 2018

Seniorenchemiker in Weimar – Chemie zwischen Klassik und Moderne (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

02. Mai. 2018

Date: 15-18 May 2018 Location: Kloster Irsee (Bavaria, Germany)

There is growing interest from academia and industry in high-temperature shape memory alloys, as these represent a fascinating field both from a basic science and an application point of view. Recent literature demonstrates that substantial progress has been made since the first conference in 2015 exclusively devoted to this topic. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

12th COMPAMED Spring Convention

02. Mai. 2018

Implants in Medical Technology (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

12. COMPAMED Frühjahrsforum

02. Mai. 2018

Implantate in der Medizintechnik (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen