Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Fahrtauglichkeit: Individuelle Gesundheitschecks für Senioren

Eingebrannt hat sich das Bild vom älteren Unfallverursacher schnell. Forderungen, wonach das Autofahren ab einem bestimmten Alter nur noch mit einem Leistungszertifikat oder verpflichtenden Gesundheitschecks erlaubt sein soll, erteilt die Deutsche Gesellschaft für Geriatrie (DGG) eine Absage. „Dieses pauschale Vorgehen ist aus medizinischer Sicht grundsätzlich abzulehnen“, sagt Professor Jürgen M. Bauer, DGG-Präsident und Lehrstuhlinhaber an der Universität Heidelberg sowie Ärztlicher Direktor des Agaplesion Bethanien Krankenhaus Heidelberg. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

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Cancer news

Artificial intelligence can determine lung cancer type

17. Sep. 2018

A new computer program can analyze images of patients‘ lung tumors, specify cancer types, and even identify altered genes driving abnormal cell growth, a new study shows. (Mehr in: Cancer News — ScienceDaily)

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Developmental stage for No. 1 eye tumor in children

17. Sep. 2018

Investigators have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the door for future interventions in retinoblastoma (RB), a tumor of the retina that affects children under five years of age. (Mehr in: Cancer News — ScienceDaily)

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New blood test detects early stage pancreatic cancer

17. Sep. 2018

Pancreatic cancer is currently very difficult to detect while it is still resectable. A new blood test can detect pancreatic cancer in the very earliest stages of the disease. (Mehr in: Cancer News — ScienceDaily)

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Daily low-dose aspirin found to have no effect on healthy life span in older people

16. Sep. 2018

In a clinical trial to determine the effects of daily low-dose aspirin in healthy older adults without previous cardiovascular events, aspirin did not prolong healthy, independent living free of dementia or physical disability. (Mehr in: Cancer News — ScienceDaily)

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Research in yeast leads to serendipitous finding about a central nervous system disorder

14. Sep. 2018

Researchers found that an important quality control mechanism in baker’s yeast is closely connected to hypomyelinating leukodystrophy, a debilitating disease found in children. The findings could indicate a therapeutic approach for this rare disease, as well as for multiple sclerosis and other neurodegenerative diseases. (Mehr in: Cancer News — ScienceDaily)

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New method promises fewer side effects from cancer drugs

14. Sep. 2018

A recent achievement in the field of protein research allows for better tailored pharmaceuticals with fewer side effects. (Mehr in: Cancer News — ScienceDaily)

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Cancer drug and antidepressants provide clues for treating brain-eating amoeba infections

13. Sep. 2018

Researchers have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the US Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen and antidepressant Prozac. (Mehr in: Cancer News — ScienceDaily)

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High-resolution genomic map gives scientists unprecedented view of brain development

13. Sep. 2018

Researchers have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth. The analysis of thousands of brain cells isolated from mice offers researchers a high-resolution map that enables scientists to view the detailed genomic changes cells undergo as the cerebellum wires its neural circuitry. (Mehr in: Cancer News — ScienceDaily)

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How a virus destabilizes the genome

13. Sep. 2018

New insights into how Kaposi’s sarcoma-associated herpesvirus induces genome instability and promotes cell proliferation could lead to the development of novel antiviral therapies for KSHV-associated cancers. (Mehr in: Cancer News — ScienceDaily)

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Pilot study identifies strain of bacteria as chief risk factor for stomach cancer

12. Sep. 2018

Researchers have found a specific strain of Helicobacter pylori strongly correlated with stomach cancer. (Mehr in: Cancer News — ScienceDaily)

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Scientists map interactions between head and neck cancer and HPV virus

12. Sep. 2018

Scientists mapped the interactions between all HPV proteins and human proteins for the first time. (Mehr in: Cancer News — ScienceDaily)

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Breast cancer screening does not reduce mortality

12. Sep. 2018

Fewer and fewer women die from breast cancer in recent years but, surprisingly, the decline is just as large in the age groups that are not screened. The decline is therefore due to better treatment and not screening for breast cancer. (Mehr in: Cancer News — ScienceDaily)

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Shedding light on 100-year-old cancer mystery

12. Sep. 2018

Using genetic and pharmacological means, scientists were surprised to find that blocking LDHA had only a limited impact on melanoma cells, since they were able to redirect energy production. Their results identify an alternative growth pathway driven by a molecule called ATF4, revealing new potential targets for drug development. (Mehr in: Cancer News — ScienceDaily)

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New method of pinpointing cancer mutations could lead to more targeted treatments

11. Sep. 2018

A team of researchers has developed a new framework that can combine three existing methods of finding large mutations in cancer cells — called structural variants — into a single, more complete picture of cancer. (Mehr in: Cancer News — ScienceDaily)

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‚Evil‘ proteins a force for good in estrogen receptor-positive breast cancer

11. Sep. 2018

Researchers have clarified questions surrounding estrogen’s role in breast cancer, which could lead to more precise treatments for ER-positive breast cancers. (Mehr in: Cancer News — ScienceDaily)

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Unusual biosynthetic pathway offers a key to future natural product discovery

11. Sep. 2018

Researchers have elucidated a mechanism of nitrogen-nitrogen bond formation shared by two pharmaceutically promising compounds. (Mehr in: Cancer News — ScienceDaily)

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New genetic compound marker could help early diagnosis of aggressive prostate cancer

11. Sep. 2018

A research team has discovered a link between the interplay of certain simultaneously occurring genetic changes in the HOXB13 and CIP2A genes, aggressiveness of prostate cancer, high risk of developing the disease, and poorer survival rates of patients. Prostate cancer is a major challenge in health care with over one million new cases and 300,000 deaths from it each year worldwide. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

11. Bundesalgenstammtisch 2018; Mikroalgen für Umwelt und Wertschöpfung

01. Sep. 2018

Der jährlich stattfindende „Bundesalgenstammtisch“ ist die deutschsprachige Kommunikationsplattform für alle, die mit der Algenbiotechnologie in Wissenschaft und Industrie befasst sind. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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4th Forum on Hydrothermal Processes "Technologies generating material and energetic added value"

01. Sep. 2018

The event will be bilingual – German and English with simultaneous translation. Presentations and posters will be available in both languages. If you are interested in participating in the event with a presentation/talk or poster, please submit your Application form by May 1st, 2018 via e-mail to htp-inno@dbfz.de.

Accepted abstracts will appear in the conference reader. For accepted posters, a short introduction (three minutes, one slide) will be provided in addition to the poster exhibiton. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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4. Tag der Arbeitsmedizin in Hannover

01. Sep. 2018

Dialogforen Arbeitsmedizin und Arbeitssicherheit – Eine Veranstaltungsreihe für Wissenschaft und Praxis der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V. (DGAUM) und RG GmbH (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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3rd European Conference on Natural Products

01. Sep. 2018

The 3rd European Conference on Natural Products will again feature recent advances in secondary metabolite research. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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18. Wissenschaftliche Jahrestagung der DGSF

01. Sep. 2018

Ich, Du und die anderen … Selbstorganisation – Selbststeuerung und die Frage nach dem Sinn

18. Wissenschaftliche Jahrestagung der DGSF vom 20.- 22. September 2018 an der Universität Oldenburg (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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18. Scientific Meeting (ScieM)

01. Sep. 2018

Am 27. und 28. September 2018 findet das 18. Scientific Meeting (ScieM) des Mukoviszidose e.V. in Bad Salzschlirf statt. Thema des diesjährigen Meetings sind „Anti-inflammatorische Therapien im Kontext des Mikrobioms in Lunge und Darm“. Mukoviszidose-Forscherinnen und -Forscher aus der ganzen Welt sind dazu eingeladen, beim Meeting über dieses zurzeit sehr relevante Forschungsthema zu diskutieren. Abstracts für Vorträge können bis zum 15. Juni 2018 eingereicht werden. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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17. Tag der Arbeitsmedizin in Berlin

01. Sep. 2018

Dialogforen Arbeitsmedizin und Arbeitssicherheit – Eine Veranstaltungsreihe für Wissenschaft und Praxis der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V. (DGAUM) und RG GmbH (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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