Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Enzyme produced in the liver promotes obesity, fatty liver disease and insulin resistance

In mice that are given a high-fat diet, an increased production of the enzyme DPP4* by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance. „In combination with our observations from additional human and cell studies, these results indicate that increased DPP4 production by the liver is the cause rather than the consequence of a fatty liver and insulin resistance,“ says the head of the study, Annette Schürmann from the German Institute for Human Nutrition Research (DIfE), a partner of the German Center for Diabetes Research (DZD). The research team led by Schürmann has now published its findings in Molecular Metabolism. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

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Cancer news

New genetic syndrome predisposes the body to cancer

22. Sep. 2017

A new syndrome caused by biallelic mutations — those produced in both gene copies inherited from the mother and father — in the FANCM gene predisposes the body to the appearance of tumors and causes rejection to chemotherapy treatments. Contrary to what scientists believed, the gene does not cause Fanconi anemia. Researchers recommend modifying the clinical monitoring of patients with these mutations. (Mehr in: Cancer News — ScienceDaily)

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Alternative splicing, an important mechanism for cancer

22. Sep. 2017

Scientists discover several alterations in this cellular process with implications in cancer by analyzing samples from more than 4,000 patients. (Mehr in: Cancer News — ScienceDaily)

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‚Labyrinth‘ chip could help monitor aggressive cancer stem cells

21. Sep. 2017

Inspired by the Labyrinth of Greek mythology, a new chip etched with fluid channels sends blood samples through a hydrodynamic maze to separate out rare circulating cancer cells into a relatively clean stream for analysis. It is already in use in a breast cancer clinical trial. (Mehr in: Cancer News — ScienceDaily)

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A rapid alternative to standard safety tests for lentiviral vectors

21. Sep. 2017

A new, publicly available test to assess the safety of cell therapy products altered by lentivirus generates results within a few hours, potentially hastening the pace at which viral immunotherapies move into clinical trial. Current assays required by the US Food and Drug Administration take about six weeks to complete. The rapid test, which does not have a significant risk of false positives, is also a fraction of the cost of the standard approach. (Mehr in: Cancer News — ScienceDaily)

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Exosomes are the missing link to insulin resistance in diabetes

21. Sep. 2017

Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now. In a new paper, researchers identified exosomes — extremely small vesicles or sacs secreted from most cell types — as the missing link. (Mehr in: Cancer News — ScienceDaily)

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Mitochondria drive cell survival in times of need

21. Sep. 2017

Researchers have discovered a mechanism through which mitochondria, the energy factory of our body’s cells, play a role in preventing cells from dying when the cells are deprived of nutrients — a finding that points to a potential target for next-generation cancer drugs. (Mehr in: Cancer News — ScienceDaily)

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Whole food diet may help prevent colon cancer, other chronic conditions

21. Sep. 2017

A diet that includes plenty of colorful vegetables and fruits may contain compounds that can stop colon cancer and inflammatory bowel diseases in pigs, according to an international team of researchers. Understanding how these compounds work on a molecular level could be an initial step toward finding treatments for people with cancer, they added. (Mehr in: Cancer News — ScienceDaily)

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New genetic test for predicting cancer recurrence

21. Sep. 2017

Researchers have discovered a new genetic test which could help predict cancer recurrence – paving the way for more precise, personalised treatments. (Mehr in: Cancer News — ScienceDaily)

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Inflammatory bowel disease in childhood associated with increased risk of cancer

21. Sep. 2017

Children diagnosed with inflammatory bowel disease have an increased risk of cancer, especially gastrointestinal cancers, both in childhood and later in life, finds a study. (Mehr in: Cancer News — ScienceDaily)

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Bio-inspired approach to RNA delivery

20. Sep. 2017

A team of chemical engineers, inspired by the way that cells translate their own mRNA into proteins, has designed a synthetic delivery system that is four times more effective than delivering mRNA on its own. (Mehr in: Cancer News — ScienceDaily)

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Brain cancer growth halted by absence of protein

20. Sep. 2017

The growth of certain aggressive brain tumors can be halted by cutting off their access to a signaling molecule produced by the brain’s nerve cells, according to a new study. (Mehr in: Cancer News — ScienceDaily)

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Researchers identify new target, develop new drug for cancer therapies

20. Sep. 2017

Opening up a new pathway to fight cancer, researchers have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant to treatment. Researchers were able to use this finding to develop a drug that successfully inhibits tumor growth of melanoma as well as pancreatic and colorectal cancer in mice. (Mehr in: Cancer News — ScienceDaily)

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Screening for cervical abnormalities in women offered HPV vaccination

19. Sep. 2017

Human papillomavirus (HPV) testing detects a higher number of precancerous cervical lesions than cytology-based Pap smears in a female population including a proportion offered HPV vaccination, according to a new study. (Mehr in: Cancer News — ScienceDaily)

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Brain powered: Increased physical activity among breast cancer survivors boosts cognition

19. Sep. 2017

It is estimated that up to 75 percent of breast cancer survivors experience problems with cognitive difficulties following treatments, perhaps lasting years. Currently, few science-based options are available to help. Researchers report in a pilot study of 87 female breast cancer survivors an increase in physical activity more than doubled the women’s post-treatment mental processing speed. (Mehr in: Cancer News — ScienceDaily)

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Scientists discover complex axis of immune suppression exploited by cancers

19. Sep. 2017

A new mechanism by which cancer cells evade destruction by the immune system has been discovered by a team of researchers. Their paper describes how immune cells known as group 2 innate lymphoid cells (ILC2s) are recruited by leukemic cells to suppress an essential anticancer immune response. (Mehr in: Cancer News — ScienceDaily)

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Guidelines for handling CAR T cell side effects

19. Sep. 2017

Immune-cell based therapies opening a new frontier for cancer treatment carry unique, potentially lethal side effects that provide a new challenge for oncologists, one addressed by proposed guidelines for systematically dealing with the toxicities of these drugs. (Mehr in: Cancer News — ScienceDaily)

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‚Language of stem cells‘ discovered

19. Sep. 2017

Stem cells control the cells around them, inducing them to perform specific functions. This phenomenon of the „language of stem cells“, which has now been discovered for the very first time, report investigators. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

22. International Biohydrometallurgy Symposium

01. Sep. 2017

Call for Papers is open – submit your contribution until 10 January 2017

The biannual International Biohydrometallurgy Symposium is the global forum for experts from academia and industry active in the fields of biomining, bioleaching and bioremediation. These technologies have a high potential to establish environmentally favourable processes for the recovery of primary and secondary precious and base metal resources as well as the remediation of exploited mining sites. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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13. Kölner Abend der Sportwissenschaft mit Wolf-Dieter Poschmann

01. Sep. 2017

Die Deutsche Sporthochschule Köln und die Gesellschaft der Freunde und Förderer laden Sie herzlich zum 13. Kölner Abend der Sportwissenschaft am 20. September 2017 (Hörsaal 1 der DSHS Köln, 19:00 Uhr) zu folgendem Thema ein:

Denksport – Aktiv gegen das Vergessen! (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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12th International Symposium on Electrokinetics

01. Sep. 2017

We are pleased to announce the 12th International Symposium on Electrokinetics to take place in Dresden, Germany from September 10 to 12, 2017. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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25. Wiss. Symposium für Psychotherapie: Veränderbarkeit – Ändern/Verändern/Anders am 13./14.10.2017

12. Aug. 2017

1992 wurde das Wissenschaftliche Symposium für Psychotherapie eingeführt. 25 Jahre später lädt die LWL-Universitätsklinik Bochum für Psychosomatische Medizin und Psychotherapie zu einem Jubiläumssymposium ein. Was hat sich verändert und welche Entwicklungen sind zu erwarten? Psychotherapie will ändern und stellt sich der Frage nach der Veränderbarkeit eines Menschen. Die Vorträge reichen von (epi)genetischen über soziologische, kulturelle bis hin zu psychotherapeutischen Themen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Bavarian Summer School 2017 – The Future of Health Care

24. Jul. 2017

From 24/07/ until 04/08/17 the first summer school organized by Study & Work International, an initiative of the Bavarian Association of Universities of Applied Sciences (UAS), takes place at the Lutheran UAS Nuremberg and the technical UAS OTH Amberg-Weiden.The Future of Health Care: New Concepts – New Technologies is the topic of this two-week interdisciplinary summer school for Bachelor’s students from the fields of health care as well as various engineering disciplines (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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15th EUROPEAN CONFERENCE ON ORGANIZED FILMS

08. Jul. 2017

The 15th European Conference on Organized Films (ECOF 15) adds to a successful series of conferences addressing latest findings and advances in the field of thin and ultrathin organic films as well as nanoscience and -technologies. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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14th Dortmund MST Conference – Individualized Healthcare Solutions

05. Jul. 2017

Embracing „Individualized Healthcare Solutions“, the 14th Dortmund MST Conference on July 5, 2017 will present microsystems, production processes and digital technologies for use in medical technology and healthcare. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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