Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Wie Sport der Demenz vorbeugt

Dass Sport die Denkleistung im Alter verbessert, haben viele Studien gezeigt. Jetzt haben Forscher der Goethe-Universität in einer der weltweit ersten Studien geklärt, wie Sport sich auf den Gehirnstoffwechsel auswirkt. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

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Cancer news

‚Liquid biopsy‘ predicts lymphoma therapy success within days

20. Aug. 2018

A blood test can predict which patients with a type of cancer called diffuse large B cell lymphoma are likely to respond positively to initial therapy and which are likely to need more aggressive treatment, according to a multicenter study. (Mehr in: Cancer News — ScienceDaily)

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Effect of radiation exposure on hormone deficiencies

20. Aug. 2018

Researchers have detailed the effect of radiation exposure on the development of hormone deficiency in pediatric and young adult patients treated for brain tumors. (Mehr in: Cancer News — ScienceDaily)

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STAT3 can be a therapeutic target for chronic active EBV infection, a fatal disorder

20. Aug. 2018

Chronic active Epstein-Barr virus infection (CAEBV) is an inflammatory disorder with potential for tumor development. Here, unusual phosphorylation was observed on STAT3 in EBV-infected T- or NK-cells from patients with CAEBV. Researchers found that ruxolitinib, a drug that is currently used for treatment of myelofibrosis and polycythemia vera, could suppress the survival of these EBV-infected cells in a dose-dependent manner, and that STAT3 could be an important new target for treatment of CAEBV. (Mehr in: Cancer News — ScienceDaily)

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New study explains why genetic mutations cause disease in some people but not in others

20. Aug. 2018

Researchers have uncovered a molecular mechanism behind one of biology’s long-standing mysteries: why individuals carrying identical gene mutations for a disease end up having varying severity or symptoms of the disease. The study has exciting implications for future prediction of the severity of serious diseases such as cancer and autism spectrum disorder. (Mehr in: Cancer News — ScienceDaily)

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Predictor for immunotherapy response in melanoma

20. Aug. 2018

In a new study, researchers developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors, a novel type of immunotherapy. (Mehr in: Cancer News — ScienceDaily)

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Gene therapy vectors carrying the telomerase gene do not increase the risk of cancer

20. Aug. 2018

Researchers have shown in a new study that the gene therapy with telomerase that they have developed, and which has proven to be effective in mice against diseases caused by excessive telomere shortening and ageing, does not cause cancer or increase the risk of developing it, even in a cancer-prone setting. (Mehr in: Cancer News — ScienceDaily)

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Nanoparticles in our environment may have more harmful effects than we think

20. Aug. 2018

Researchers warn that a combination of nanoparticles and contaminants may form a cocktail that is harmful to our cells. In their study, 72 pct. of cells died after exposure to a cocktail of nano-silver and cadmium ions. (Mehr in: Cancer News — ScienceDaily)

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New drug could prevent debilitating side effect of cancer treatment

20. Aug. 2018

About 50,000 people in the US are diagnosed annually with head, neck, nasal and oral cancers. Most are treated with radiation, and of those, 70-80 percent develop a painful and debilitating side effect called severe oral mucositis. A new drug could potentially prevent the condition. (Mehr in: Cancer News — ScienceDaily)

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E-cigarettes can damage DNA

20. Aug. 2018

The popularity of electronic cigarettes continues to grow worldwide, as many people view them as a safer alternative to smoking. But the long-term effects of e-cigarette usage, commonly called ‚vaping,‘ are unknown. Today, researchers report that vaping may modify the genetic material, or DNA, in the oral cells of users, which could increase their cancer risk. (Mehr in: Cancer News — ScienceDaily)

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A GPS for inside your body

20. Aug. 2018

Scientists have developed a system that can pinpoint the location of ingestible implants inside the body using low-power wireless signals. (Mehr in: Cancer News — ScienceDaily)

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Weaponizing oxygen to kill infections and disease

19. Aug. 2018

The life-threatening bacteria MRSA can cripple a medical facility since it is resistant to treatment. But scientists report that they are now making advances in a new technique that avoids antibiotics, instead using light to activate oxygen, which wipes out bacteria. The method also could be used to treat other microbial infections, and possibly even cancer. (Mehr in: Cancer News — ScienceDaily)

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Insight into development of lung cancer

18. Aug. 2018

Lung cancer results from effects of smoking along with multiple genetic components. A new study identifies two main pathways for the role of chromosome 15q25.1 — a leader in increasing susceptibility to lung cancer — in modifying disease risk. One pathway is implicated in nicotine dependence. The other plays a part in biological processes such as nutrient transfer and immune system function. The findings increase our understanding of lung cancer cause and development. (Mehr in: Cancer News — ScienceDaily)

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Like shark attacks and the lottery, unconscious bias influences cancer screening

17. Aug. 2018

Study shows that doctors with personal experience of cancer are more likely to act against established guidelines to recommend that low-risk women receive ovarian cancer screening. (Mehr in: Cancer News — ScienceDaily)

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Exploring the relationship between fever and cancer incidence

17. Aug. 2018

In a new paper, researchers propose a mechanistic hypothesis that focuses on the potential impact infectious fever has on a particular subset of T cells, known as gamma/delta T cells. (Mehr in: Cancer News — ScienceDaily)

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New CRISPR technique skips over portions of genes that can cause disease

16. Aug. 2018

In a new study in cells, researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. Such targeted editing could one day be useful for treating genetic diseases caused by mutations in the genome, such as Duchenne’s muscular dystrophy, Huntington’s disease or some cancers. (Mehr in: Cancer News — ScienceDaily)

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Diagnosing cancer with malaria protein: New method discovered

16. Aug. 2018

Researchers have discovered a method of diagnosing a broad range of cancers at their early stages by utilizing a particular malaria protein, which sticks to cancer cells in blood samples. The researchers hope that this method can be used in cancer screenings in the near future. (Mehr in: Cancer News — ScienceDaily)

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Retinoic acid may improve immune response against melanoma

16. Aug. 2018

Clinical trial results describe a promising strategy to remove one of melanoma’s most powerful defenses: By adding retinoic acid to standard-of-care treatment, researchers were able to turn off myeloid-derived suppressor cells (MDSCs) that turn off the immune system, leading to more immune system activity directed at melanoma. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

10. TWINCORE Symposium – Frontiers in translational infection research

01. Aug. 2018

Am 31. August 2018 begrüßen wir zum 10. Mal Wissenschaftlerinnen und Wissenschaftler asu der ganzen Welt zum TWINCORE Symposium. Internationale Experten führen durch aktuelle Entwicklungen der translationalen Infektionsforschung.

http://www.twincore.de/twincore/

Nähere Informationen folgen… (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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„Blue Biotechnology in the Baltic Sea Region – from Science to Business“

01. Aug. 2018

Es ist uns eine große Freude, Sie zu der internationalen Konferenz „Blue Biotechnology in the Baltic Sea Region – from Science to Business“ einzuladen. Rund 100 Wissenschaftler, Unternehmer und Interessenvertreter aus dem Umfeld der marinen Biotechnologie werden vom 22. bis zum 24. August 2018 neueste Resultate aus Forschung und Entwicklung sowie erfolgreiche ökonomische Umsetzungen präsentieren. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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12th International Conference and Workshop on Biological Barriers

01. Aug. 2018

Biological Barriers is an international scientific event , organized every two years and receiving constantly 200+ registered attendees from all over the world. In the focus of BioBarriers are human cell and tissue models for facilitating clinical translation of new drugs and delivery systems, especially in the context of infectious diseases. Moreover, we will discuss innovative concepts and materials, also capable to overcome non-cellular diffusion barriers such as mucus or bacterial biofilms. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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OSTSEETAG

01. Aug. 2018

Wer Ostsee-Expertenwissen braucht, ist hier richtig: 3. Ostseetag im Stadthafen Rostock! (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Klinische Bewertung medizinischer Software

01. Aug. 2018

Für jedes Medizinprodukt muss der Hersteller anhand klinischer Daten die Eignung für die vorgesehene Verwendung nachweisen und die klinischen Risiken vor dem Hintergrund des zu erwartenden Nutzens für den Patienten bewerten. Dies ist ein kontinuierlicher Prozess, der sich bis zur klinischen Nachbeobachtung nach dem Inverkehrbringen erstreckt. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Sommerkolleg: Chemie, Physik und Materialwissenschaften

01. Jul. 2018

Das Sommerkolleg bietet Interessierten ab 16 Jahren die Möglichkeit einen vertieften Einblick in das Studium der Chemie und Physik sowie der Materialwissenschaften mit Vorlesungen und Praktika zu gewinnen. Es werden Praktika in der Anorganischen Chemie, der Organischen Chemie, in der Physik, Werkstofftechnik und Umformtechnik angeboten, sowie ein Einführungskurs in die Themenfelder Glas-Bindemittel und Kunststoffverarbeitung. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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RVZ Kolloquium: Prof. Michael Rape

01. Jul. 2018

Prof. Michael Rape from UC Berkeley (US) will talk about his research „The other code: roles of ubiquitin in neuronal development and neurodegeneration“ at the Rudolf Virchow Center of the University of Würzburg. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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