Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Blocking cancer: Scientists find new way to combat disease

A newly developed compound shows promise for blocking cancer-causing proteins on a cellular level, outlines a new report. (Mehr in: Cancer News — ScienceDaily)

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Cancer news

How a poorly explored immune cell may impact cancer immunity and immunotherapy

17. Nov. 2017

The immune cells that are trained to fight off the body’s invaders can become defective. It’s what allows cancer to develop. So most research has targeted these co-called effector T-cells. But a new study takes a step back and considers: What if the problem isn’t with the effector T-cells but starts higher up the cellular chain? (Mehr in: Cancer News — ScienceDaily)

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Protein key to cancer cells ability to spread identified

17. Nov. 2017

Scientists have made a discovery that could reduce the spread of cancer by hindering a protein that binds cancer cells together and allows them to invade tissues. The groundbreaking study identified a protein, known as cadherin-22, as a potential factor in cancer metastasis, or spread, and showed that hindering it decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 percent. (Mehr in: Cancer News — ScienceDaily)

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Link between obesity and cancer is not widely recognized

17. Nov. 2017

A new study has shown that the majority of people in the United Kingdom do not understand the connection between weight issues and cancer. Obesity is associated with thirteen types of cancer, including those of the breast, kidney, bowel, and womb. However, after surveying 3293 adults, taken as representative of the UK population, researchers found that only a quarter of respondents were aware of the link between obesity and cancer. (Mehr in: Cancer News — ScienceDaily)

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Novel therapeutic target discovered for estrogen receptor positive (ER+) breast cancer

17. Nov. 2017

A new protein has been identified in a common subtype of breast cancer which can potentially offer more effective therapies for the future. (Mehr in: Cancer News — ScienceDaily)

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Computer program finds new uses for old drugs

16. Nov. 2017

Researchers have developed a computer program to find new indications for old drugs. The computer program, called DrugPredict, matches existing data about FDA-approved drugs to diseases, and predicts potential drug efficacy. In a recent study, the researchers successfully translated DrugPredict results into the laboratory, and showed common pain medications — like aspirin — can kill patient-derived epithelial ovarian cancer cells. (Mehr in: Cancer News — ScienceDaily)

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Ancient enzyme could boost power of liquid biopsies to detect and profile cancers

16. Nov. 2017

Researchers are developing a new tool for liquid biopsy that can detect RNA biomarkers from cancer cells in a patient’s blood much more accurately and completely than other existing methods. This could soon provide doctors with a more complete picture of an individual’s disease, improving their chances of finding the best treatment, while also sparing patients the pain, inconvenience and long wait times associated with surgical biopsies. (Mehr in: Cancer News — ScienceDaily)

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Wider sampling of tumor tissues may guide drug choice, improve outcomes

15. Nov. 2017

By focusing on genetic variations within a primary tumor, differences between the primary and a metastatic tumor, and additional diversity from tumor DNA in the blood stream, physicians can make better treatment choices for patients with gastric and esophageal adenocarcinoma. This study challenges current guidelines and supports evaluation of metastatic lesions and circulating tumor DNA. (Mehr in: Cancer News — ScienceDaily)

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Key to unlock blocked differentiation in microRNA-deficient embryonic stem cells

15. Nov. 2017

Scientists have partly solved a long-unanswered basic question about stem cells — why are pluripotent stem cells that have mutations to block the production of microRNAs unable to differentiate? (Mehr in: Cancer News — ScienceDaily)

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Development of new protein may lead to novel treatment options for cancer, birth defects

14. Nov. 2017

An artificial protein has been engineered that may block malignant properties of cancer cells as well as correct certain birth defects. The findings may lead to identifying new molecular targets suitable for therapeutic intervention. (Mehr in: Cancer News — ScienceDaily)

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Why testicular cancer is so responsive to chemo

14. Nov. 2017

A major step has been taken toward answering a key question in cancer research: Why is testicular cancer so responsive to chemotherapy, even after it metastasizes? (Mehr in: Cancer News — ScienceDaily)

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Sensor for the most important human cancer gene

14. Nov. 2017

The molecular smoke detector works like a TP53 sensor, which monitors the correct function of the gene. A non-functional TP53 gene is going to activate the sensor, which initiates cell death. (Mehr in: Cancer News — ScienceDaily)

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Tapeworm drug fights prostate cancer

14. Nov. 2017

Medicine against parasites like Tapeworms and Giardia, contains a substance that kills Prostate- and colon cancer, scientists have discovered. (Mehr in: Cancer News — ScienceDaily)

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HPV testing is better than the Pap test at detecting cervical cancer

14. Nov. 2017

Testing for cervical cancer using HPV testing in addition to the Pap smear is unlikely to detect cancer cases that wouldn’t be found using HPV testing alone. (Mehr in: Cancer News — ScienceDaily)

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Insurance linked to black-white survival disparities in colorectal cancer

14. Nov. 2017

Health insurance coverage differences account for nearly one-half of the black-white survival disparity in colorectal cancer patients, according to a new study. (Mehr in: Cancer News — ScienceDaily)

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Effective therapy against glioblastoma by attacking telomeres

13. Nov. 2017

Researchers have shown that it is possible to block the growth of human and murine glioblastoma in mouse models by blocking the TRF1 protein; an essential component of the telomere-protective complex. The study describes a new and promising way to combat this type of brain tumor by attacking its ability to regenerate and divide immortally. (Mehr in: Cancer News — ScienceDaily)

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Genes that hold the clues to bladder cancer and its treatment

13. Nov. 2017

Scientists have discovered the ‚genetic signatures‘ of the most common form of bladder cancer — and it could open up the possibility of better-targeted treatment. (Mehr in: Cancer News — ScienceDaily)

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Harder for T cells to fight cancer in absence of VEGF-A

13. Nov. 2017

Contrary to what was previously believed, the immune system’s cancer-killing T cells are more effective in a tumor’s anoxic environment when they have access to growth factor VEGF-A. Researchers now show how the T cells not only survive in this oxygen-depleted micro-environment with the help of transcription factor HIF-1a but also become more effective at killing cancer cells inside it. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

Air Pollution and Health: New Research Perspectives for a Growing Global Crisis

01. Nov. 2017

Joint symposium by the Academy of Science of South Africa and the Leopoldina (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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6. Morbi-RSA Symposium

01. Nov. 2017

Eigentlich soll der morbiditätsorientierte Risikostrukturausgleich – kurz: Morbi-RSA – den Finanzausgleich zwischen den gesetzlichen Krankenversicherungen regeln. Fakt ist: Die Kassen haben nach wie vor die Möglichkeit, ärztliche Diagnosen zu beeinflussen, um so höhere Zuwendungen aus dem Gesundheitsfonds zu erreichen. Das geht aus einem Gutachten des Berliner IGES Instituts hervor – und liefert jede Menge Zündstoff für das 6. Morbi-RSA Symposium am 20. November 2017 in Essen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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20. Gesundheitspolitisches Kolloquium

01. Nov. 2017

Wer übernimmt die Verantwortung in der Notfallversorgung? 20. Gesundheitspolitisches Kolloquium an der Frankfurt UAS diskutiert Optionen der Notfallversorgung in Hessen (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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20. Deutsche Mukoviszidose Tagung

01. Nov. 2017

Biomarker im klinischen Alltag, Problemkeime jenseits des Pseudomonas, die Bedeutung von Physiotherapie in der Mukoviszidose-Behandlung – dies sind nur einige Beispiele für das breite Themenspektrum der Deutschen Mukoviszidose Tagung, die vom 16. bis 18. November 2017 in Würzburg stattfindet. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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13. Kolloquium Prozessanalytik: Prozessführung in der modernen Produktion

01. Nov. 2017

Was kann die Prozessindustrie im Hinblick auf die „Industrie 4.0“ von der Fertigungstechnik lernen? Mit dieser Frage schlägt das 13. Kolloquium „Prozessanalytik“ die Brücke zwischen zwei technologischen Bereichen, die für die chemisch/pharmazeutische Prozessindustrie aktueller denn je sind. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Biologisierung der Medizintechnik – Workshop VII – Biomaterial – Immunsystem Wechselwirkungen

01. Nov. 2017

Wechselwirkungen zwischen Biomaterialien und dem Organismus können zu Problemen führen oder Chancen eröffnen. Die Einflüsse reichen vom Biofouling während des Erstkontaktes bis hin zu Implantatverlusten. Eine zentrale Rolle spielt das Immunsystem, das viele dieser Reaktionen koordiniert. Ziel ist es deshalb, ein rationales Design von Biomaterialien mit immunmodulierenden Eigenschaften zu erreichen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Akademievorlesung "Willkommen in Utopia." | 16.11.2017 18:00 Uhr – 20:00 Uhr

01. Nov. 2017

Mit der Akademievorlesung zieht die Interdisziplinare Arbeitsgruppe „Gentechnologiebericht“ 16 Jahre nach ihrer Gründung Bilanz anlässlich eines heute wie damals höchst umstrittenen und viel diskutierten Forschungsbereichs. In Expertenbeiträgen und Podiumsdiskussionen werden die Gentechnologien dabei sowohl in ihrer historischen und zukünftigen Entwicklung als auch in ihrer aktuellen gesellschafts- und forschungspolitischen Relevanz eingeordnet. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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