Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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First 3-D map of cell-building protein linked to cancer

Researchers have revealed, for the first time, the three-dimensional molecular ‚map‘ of a protein that has been pinpointed as a driver of many types of cancers. (Mehr in: Cancer News — ScienceDaily)

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Cancer news

miR-122 target sites in liver cancer: study links three genes to patient survival

22. Aug. 2017

A new study shows that a molecule that regulates liver-cell metabolism and suppresses liver-cancer development interacts with thousands of genes in liver cells, and that when levels of the molecule go down, such as during liver-cancer development, the activity of certain cancer-promoting genes goes up. The findings could one day help doctors better predict survival in liver cancer patients and help determine whether the molecule — called microRNA-122 — should be developed as an anticancer drug. (Mehr in: Cancer News — ScienceDaily)

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New targets for drugs to treat fatty liver disease and liver cancer

21. Aug. 2017

There may no silver bullet for treating liver cancer or fatty liver disease, but knowing the right targets will help science develop the most effective treatments. Researchers have just identified a number of drug targets that can be used in the development of new efficient treatment strategies with minimum side effects. (Mehr in: Cancer News — ScienceDaily)

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Vitamin C regulates stem cell function, curbs leukemia development, scientists discover

21. Aug. 2017

Not much is known about stem cell metabolism, but a new study from the Children’s Medical Center Research Institute at UT Southwestern has found that stem cells take up unusually high levels of vitamin C, which then regulates their function and suppresses the development of leukemia. (Mehr in: Cancer News — ScienceDaily)

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Searching for the ‚signature‘ causes of BRCAness in breast cancer

21. Aug. 2017

Breast cancer cells with defects in the DNA damage repair-genes BRCA1 and BRCA2 have a mutational signature known in cancer genomics as ‚Signature 3.‘ But not all breast tumor cells exhibiting Signature 3 have BRCA1 or BRCA2 mutations. Therefore, some consider Signature 3 a biomarker for ‚BRCAness,‘ a sign of a breakdown in BRCA-related DNA repair in general and not BRCA damage in particular. (Mehr in: Cancer News — ScienceDaily)

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Comprehensive genomic analysis offers insights into causes of Wilms tumor development

21. Aug. 2017

Mutations involving a large number of genes converge on two pathways during early kidney development that lead to Wilms tumor, new research concludes. (Mehr in: Cancer News — ScienceDaily)

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How a non-coding RNA encourages cancer growth and metastasis

21. Aug. 2017

A pro-tumor environment in the cell can encourage a gene to produce an alternative form of RNA that enables cancer to spread, report researchers. (Mehr in: Cancer News — ScienceDaily)

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Many young cancer patients do not receive adequate fertility information and support

21. Aug. 2017

All cancer patients of reproductive age should be provided with fertility information and referrals for fertility preservation, researchers urge. (Mehr in: Cancer News — ScienceDaily)

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Newly developed nomograms provide accurate predictions for patients with oropharyngeal cancer

21. Aug. 2017

Researchers recently developed and validated a nomogram that can predict 2-year and 5-year overall survival (OS) and progression-free survival (PFS) for patients with local-regionally advanced oropharyngeal squamous cell carcinoma (OPSCC) treated primarily with radiation-based therapy. (Mehr in: Cancer News — ScienceDaily)

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Spaser can detect, kill circulating tumor cells to prevent cancer metastases, study finds

21. Aug. 2017

A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells in the blood stream and then killing these cells, according to a new research study. (Mehr in: Cancer News — ScienceDaily)

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Comparison of screening recommendations indicates annual mammography

21. Aug. 2017

When to initiate screening for breast cancer, how often to screen, and how long to screen are questions that continue to spark emotional debates. (Mehr in: Cancer News — ScienceDaily)

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Study of California kidney cancer shows declining incidence, end of a trend

18. Aug. 2017

A study of kidney cancer incidence in California over 25 years is the first report to demonstrate that the rising rate of kidney cancer seen in the US over the past two decades may have ended. (Mehr in: Cancer News — ScienceDaily)

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Histone 1, the guardian of genome stability

18. Aug. 2017

Genomic instability is the main risk factor for tumor development in humans. Therefore understanding its origin and and exploring therapeutic targets is paramount. Histone 1 silences a region of the genome that causes irreparable DNA damage when translated and is lethal for the organism. (Mehr in: Cancer News — ScienceDaily)

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A better way to measure mortality trends?

17. Aug. 2017

A new study suggests long-term mortality trends may be better understood by focusing on life-years lost — remaining life expectancy for a decedent — instead of solely looking at cause of death. (Mehr in: Cancer News — ScienceDaily)

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Gold nanostars and immunotherapy vaccinate mice against cancer

17. Aug. 2017

By combining an FDA-approved cancer immunotherapy with an emerging tumor-roasting nanotechnology, researchers improved the efficacy of both therapies in a proof-of-concept study using mice. The potent combination also attacked satellite tumors and distant cancerous cells, completely curing two mice and effectively vaccinating one against the disease. (Mehr in: Cancer News — ScienceDaily)

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New terahertz imaging approach could speed up skin cancer detection

17. Aug. 2017

Researchers have developed a new terahertz imaging approach that, for the first time, can acquire micron-scale resolution images while retaining computational approaches designed to speed up image acquisition. (Mehr in: Cancer News — ScienceDaily)

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New Pathology Atlas maps genes in cancer to accelerate progress in personalized medicine

17. Aug. 2017

A new Pathology Atlas is launched today with an analysis of all human genes in all major cancers showing the consequence of their corresponding protein levels for overall patient survival. The difference in expression patterns of individual cancers observed in the study strongly reinforces the need for personalized cancer treatment based on precision medicine. (Mehr in: Cancer News — ScienceDaily)

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Scientists develop novel immunotherapy technology for prostate cancer

17. Aug. 2017

A novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA to directly encode protective antibodies against a cancer-specific protein has been described in a new article. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

25. Wiss. Symposium für Psychotherapie: Veränderbarkeit – Ändern/Verändern/Anders am 13./14.10.2017

12. Aug. 2017

1992 wurde das Wissenschaftliche Symposium für Psychotherapie eingeführt. 25 Jahre später lädt die LWL-Universitätsklinik Bochum für Psychosomatische Medizin und Psychotherapie zu einem Jubiläumssymposium ein. Was hat sich verändert und welche Entwicklungen sind zu erwarten? Psychotherapie will ändern und stellt sich der Frage nach der Veränderbarkeit eines Menschen. Die Vorträge reichen von (epi)genetischen über soziologische, kulturelle bis hin zu psychotherapeutischen Themen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Bavarian Summer School 2017 – The Future of Health Care

24. Jul. 2017

From 24/07/ until 04/08/17 the first summer school organized by Study & Work International, an initiative of the Bavarian Association of Universities of Applied Sciences (UAS), takes place at the Lutheran UAS Nuremberg and the technical UAS OTH Amberg-Weiden.The Future of Health Care: New Concepts – New Technologies is the topic of this two-week interdisciplinary summer school for Bachelor’s students from the fields of health care as well as various engineering disciplines (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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15th EUROPEAN CONFERENCE ON ORGANIZED FILMS

08. Jul. 2017

The 15th European Conference on Organized Films (ECOF 15) adds to a successful series of conferences addressing latest findings and advances in the field of thin and ultrathin organic films as well as nanoscience and -technologies. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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14th Dortmund MST Conference – Individualized Healthcare Solutions

05. Jul. 2017

Embracing „Individualized Healthcare Solutions“, the 14th Dortmund MST Conference on July 5, 2017 will present microsystems, production processes and digital technologies for use in medical technology and healthcare. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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14. Dortmunder MST-Konferenz – Individualisierte Gesundheitslösungen

05. Jul. 2017

Unter dem Motto „Individualisierte Gesundheitslösungen“ präsentiert die 14. Dortmunder MST-Konferenz am 5. Juli 2017 Mikrosysteme, mikrotechnische Fertigungsverfahren und digitale Technologien für den Einsatz in der Medizintechnik und Gesundheitsversorgung. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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8th International Triticeae Symposium 2017

02. Jun. 2017

This symposium includes four main themes:

Taxonomy, Phylogeny and Phytogeography Biodiversity and Conservation Genetics and Genomics Breeding and Utilization (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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8. Bayerischer Fachkongress Glücksspiel

02. Jun. 2017

Am 28. Juni 2017 findet der 8. Bayerische Fachkongress Glücksspiel im Novotel München City statt. Der Kongress läuft dieses Jahr unter dem Motto Migration – Trauma – Glücksspiel (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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