Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

[ read more ]

Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

[ read more ]

Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

[ read more ]

Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

[ read more ]

A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

[ read more ]

A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

[ read more ]

Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

[ read more ]

Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

[ read more ]

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

[ read more ]

About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

[ read more ]

Meldungen aus der Wissenschaft

Hirnserie: Schwindel als Krankheit

22. Okt. 2017

Wenn die Welt ins Wanken gerät.

Schwindel gilt nicht als Krankheit, aber er ist dennoch oft dringend therapiebedürftig und wird ebenso oft falsch behandelt. Vieles ist möglich und hilft – vor allem, wenn der Rhythmus stimmt.

(Mehr in: Medizin & Ernährung – FAZ.NET)

JUNGES KREBSPORTAL mit Springer Medizin CharityAward 2017 ausgezeichnet

20. Okt. 2017

Bundesweit einzigartiges Projekt der Deutschen Stiftung für junge Erwachsene mit Krebs gewürdigt (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Feierliche Eröffnung des Wintersemesters 2017/18

20. Okt. 2017

Fakultäten übergreifender Gottesdienst in der Hochschulkirche (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Forscher untersuchen Pflanzenkohle als Basis für umweltfreundlichen Langzeitdünger

20. Okt. 2017

Ein Team aus Forscherinnen und Forschern der Universität Tübingen, der Hochschule Geisenheim und weiteren internationalen Partnern klären den Mechanismus der Nitratspeicherung in Pflanzenkohle bei der Kompostierung auf (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Rhythmus der Erinnerung

20. Okt. 2017

Gehemmte Neuronen wirken als Taktgeber für Gedächtnisprozesse (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

„Freiräume für die Forschung“ 150.000 €-Ehrung stärkt Pflanzenforschung um Prof. Dr. Schmid

20. Okt. 2017

Gips-Schüle-Stiftung vergibt Auszeichnung an Prof. Dr. Karl Schmid zur Vorbereitung großer Forschungsvorhaben / Feierliche Vergabe im Balkonsaal von Schloss Hohenheim (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Today’s 65-Year-Olds Are Fitter Than Earlier Generations

20. Okt. 2017

Compared to their counterparts twenty years ago, today’s 65-year-olds not only feel younger but are generally healthier overall – and enjoy greater life satisfaction. That is just one of the latest results of the Interdisciplinary Longitudinal Study on Adult Development and Aging (ILSE) that was launched in 1993 at the Institute of Gerontology at Heidelberg University. The latest round of data collection was recently completed. The participating scientists, including researchers from Heidelberg University Hospital and the University of Leipzig, will present their findings at the Heidelberg Symposium on Interdisciplinary Collaboration in Social Psychiatry at the end of October 2017. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Beiträge

Mitochondria and the evolutionary roots of cancer

23. Feb. 2015

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to inhibitory signals, evasion of programmed cell death and limitless replicative potential with a potential for the invasion of other organs. Cancer disease is widespread among metazoans. Some properties of cancer cells such as uncontrolled cell proliferation, lack of apoptosis, hypoxia, fermentative metabolism and free cell motility, i.e. metastasis, resemble a prokaryotic lifestyle, which leads to the assumption of a reversal like evolution from eucariotic back to proteobacterial state. This phenotype matches the phenotype of the last universal common ancestor (LUCA) that resulted from the endosymbiosis between archaebacteria and α-proteobacteria, which later became the mitochondria.

 Davila AF and Zamorano P (2013) Mitochondria and the evolutionary roots of cancer. Phys. Biol. 10 (2013) 026008, doi:10.1088/1478-3975/10/2/026008

About metabolism of a carcinoma cell

23. Feb. 2015

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection.

Warburg O, Posener K, Negelein E. (1924) Über den Stoffwechsel der Carcinomzelle. Biochem Z. 152, 309–344.

A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

23. Feb. 2015
Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming

Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abrupt shifts in diseases. Discrete changes in nuclear gene expression in response to small increases in DNA mutant level are analogous to the phase shifts that is well known in physics: As heat is added, the ice abruptly turns to water or with more heat abruptly to steam. Therefore, a quantitative change that is an increasing proportion of mitochondrial DNA mutation results in a qualitative change  which coordinate changes in nuclear gene expression together with discrete changes in clinical symptoms.

 Wallace DC (2005) A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine. Annu Rev Genet. 2005 ; 39: 359. doi:10.1146/annurev.genet.39.110304.095751

Picard M et. Al (2014) Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming. PNAS E4033–E4042, doi: 10.1073/pnas.1414028111

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

23. Feb. 2015

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among tissues is attributable to environmental factors or inherited predispositions. The majority is due to bad luck, that is, random mutations arising during DNA replication in normal, noncancerous stem cells.

Tomasetti C, Vogelstein B (2015): Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science 2 January 2015: Vol. 347 no. 6217 pp. 78-81 DOI: 10.1126/science.1260825

Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

23. Feb. 2015

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline solid. However, living organisms are essentially isothermal. Because of very little differences in temperature between different parts of a cell it is assumed that energy flow in living organisms is mediated by differences in the turnover time of various metabolic processes in the cell, which occur in cyclical fashion. It has been shown that the cycle time of these metabolic processes is related to the metabolic rate, that is the rate at which the organism transforms the free energy of whatever source into metabolic work, maintenance of constant temperature and structuraland functional organization of the cells. Quantum Metabolism exploits the methodology of the quantum theory of solids to provide a molecular level which derives new rules relating metabolic rate and body size.

Davies P, Lloyd A, Demetrius LA, Tuszynski, JA (2012) Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression. Citation: AIP Advances 2, 011101 (2012); doi: 10.1063/1.3697850

Einstein A (1920), Schallausbreitung in teilweise dissozieirten Gasen

Einstein A (1924) Quantentheorie des einatomigen, idealen Gases

Quantum entanglement between the electron clouds of nucleic acids in DNA

23. Feb. 2015

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy of the molecule. Derived in the limit of long distances and periodic potentials analytic expressions linking the entanglement witnesses to the energy reduction due to the quantum entanglement in the electron clouds.

Rieper E, Anders J, Vedral V (2011) Quantum entanglement between the electron clouds of nucleic acids in DNA. arxiv.org/abs/1006.4053

 

Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

23. Feb. 2015

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is the quantum potential which sustains intimately within the underlying implicates order and the quantum processes are driven by information from quantum potential. A global quantum field of a cell, which can be described as a super orbital, provides many levels of interactions among all particles of a cell. From quantum metabolism pint of view all electrons that are contained in one system are inseparable from eachother. In a cell the cytoplasm is a gel made of up to 30% proteins, and the structure of this gel is very much like a liquid crystal which provides collective properties of the electrons.

All these electrons within this super orbital of molecules and co-enzymes of the cell, including all the many small molecules embedded in these large biomolecules, and cofactors transporting electrons are making up one huge structure that is a global cell orbital.

Bohm D (1980) Wholeness and implicate order. Routledge Classics Eds., London and New York 191-247.

Ventegodt S, Hermansen TD, Flensborg-Madsen T, Nielsen ML and Merrick J (2006) A theory of “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior. The Scientific World Journal 6, 1441-1453.

Quantum Tunnelling to the Origin and Evolution of Life

23. Feb. 2015

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital importance for life: physical and chemical processes can be traced directly back to the effects of quantum tunnelling. These processes include the   prebiotic chemistry as well as the function of biomolecular nanomachines and has many highly important implications that can be derived from to the field of molecular, prebiotic chemistry and biological evolution, respectively.

Trixler, F (2013) Quantum Tunnelling to the Origin and Evolution of Life. Curr Org Chem. 2013 Aug; 17(16): 1758–1770. doi: 10.2174%2F13852728113179990083

Quantum Teleportation and Von Neumann Entropy

23. Feb. 2015

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is dominantly responsible for the joint entropy at the final stage. If it is far from the computational basis, this dominant responsibility is moved into the quantum measurement of system. Therefore, the relative entropy can be regarded as a measure for distance between two different quantum states like trace distance or fidelity. Some relative entropies become infinity, which indicates the non-trivial intersection of the support of one quantum state with kernel of the other quantum state.

You Hwan Ju, Eylee Jung1, Mi-Ra Hwang, D. K. Park, Hungsoo Kim, Min-Soo Kim, Jin-Woo Son, Sahng-Kyoon Yoo, S. Tamaryan (2007) Quantum Teleportation and Von Neumann Entropy. arXiv:0707.1227v1

A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

23. Feb. 2015

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination – still below heating threshold – may selectively target centrioles, impair mitosis and be a beneficial therapy against malignancy. If centrioles utilize quantum photons for entanglement, properties of centrosomes/centrioles approached more specifically could be useful for therapy. Healthy centrioles for a given organism or tissue differentiation should then have specific quantum optical properties detectable through some type of readout technology. An afflicted patient’s normal cells could be examined to determine the required centriole properties which may then be used to generate identical quantum coherent photons administered to the malignancy. In this mode the idea would not be to destroy the tumor – relatively low energy lasers would be used – but to “reprogram” or redifferentiate the centrioles and transform the tumor back to healthy well differentiated tissue.

Hameroff, SR (2004) A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation. BioSystems 77, 119–136

Cancer news

Breast cancer risk quantified based on rare variants and background risk

21. Okt. 2017

Rare variants combined with background genetic risk factors may account for many unexplained cases of familial breast cancer, and knowing the specific genes involved could inform choice of prevention and treatment strategies, according to new findings. (Mehr in: Cancer News — ScienceDaily)

- Read more

How obesity promotes breast cancer

20. Okt. 2017

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result. The research team has already been able to halt this mechanism with an antibody treatment. (Mehr in: Cancer News — ScienceDaily)

- Read more

Can an aspirin a day keep liver cancer away?

20. Okt. 2017

A new study found that daily aspirin therapy was significantly associated with a reduced risk in hepatitis B related liver cancer. (Mehr in: Cancer News — ScienceDaily)

- Read more

New function in gene-regulatory protein discovered

20. Okt. 2017

Researchers show how the protein CBP affects the expression of genes through its interaction with the basal machinery that reads the instructions in our DNA. (Mehr in: Cancer News — ScienceDaily)

- Read more

Gut bacteria from wild mice boost health in lab mice

19. Okt. 2017

Laboratory mice that are given the gut bacteria of wild mice can survive a deadly flu virus infection and fight colorectal cancer dramatically better than laboratory mice with their own gut bacteria, researchers report. (Mehr in: Cancer News — ScienceDaily)

- Read more

Gene circuit switches on inside cancer cells, triggers immune attack

19. Okt. 2017

Researchers have developed a synthetic gene circuit that triggers the body’s immune system to attack cancers when it detects signs of the disease. (Mehr in: Cancer News — ScienceDaily)

- Read more

One to 10 mutations are needed to drive cancer, scientists find

19. Okt. 2017

For the first time, scientists have provided unbiased estimates of the number of mutations needed for cancers to develop, in a study of more than 7,500 tumors across 29 cancer types. Researchers have adapted a technique from the field of evolution to confirm that, on average, one to ten driver mutations are needed for cancer to emerge. (Mehr in: Cancer News — ScienceDaily)

- Read more

Gut bacterium indirectly causes symptoms by altering fruit fly microbiome

19. Okt. 2017

CagA, a protein produced by the bacterium Helicobacter pylori, can alter the population of microbes living in the fruit fly gut, leading to disease symptoms, according to new research. (Mehr in: Cancer News — ScienceDaily)

- Read more

New machine learning system can automatically identify shapes of red blood cells

19. Okt. 2017

Using a computational approach known as deep learning, scientists have developed a new system to classify the shapes of red blood cells in a patient’s blood. The findings, published in PLOS Computational Biology, could potentially help doctors monitor people with sickle cell disease. (Mehr in: Cancer News — ScienceDaily)

- Read more

Fundamental research enhances understanding of major cancer gene

19. Okt. 2017

Scientists have provided new insights into the role of PTEN, a major cancer gene, in controlling cell growth and behavior. PTEN is the second most commonly altered gene in human cancers, particularly prostate cancers, and this work could help to develop and target new treatments. (Mehr in: Cancer News — ScienceDaily)

- Read more

Key molecular link in major cell growth pathway

19. Okt. 2017

A team of scientists has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth. The researchers‘ findings also implicate a new protein, SLC38A9, as a potential drug target in pancreatic cancer. (Mehr in: Cancer News — ScienceDaily)

- Read more

New findings explain how UV rays trigger skin cancer

18. Okt. 2017

Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the US in 2017, according to the Centers for Disease Control and Prevention. A fraction of those melanomas come from pre-existing moles, but the majority of them come from sources unknown — until now. (Mehr in: Cancer News — ScienceDaily)

- Read more

Researchers release the brakes on the immune system

18. Okt. 2017

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural “brakes” in the immune defense mechanism, which normally prevent an excessive immune response. Researchers have now been able to take off one of these brakes. The study could pave the way for more effective cancer therapies, they say. (Mehr in: Cancer News — ScienceDaily)

- Read more

Yeast spotlights genetic variation’s link to drug resistance

18. Okt. 2017

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists show that high genetic diversity can prime new mutations that cause drug resistance. The study has implications for our understanding of the evolution of resistance to antimicrobial and anticancer drugs. (Mehr in: Cancer News — ScienceDaily)

- Read more

Battling flames increases firefighters‘ exposure to carcinogens

18. Okt. 2017

The threat of getting burned by roaring flames is an obvious danger of firefighting, but other health risks are more subtle. For example, firefighters have been found to develop cancer at higher rates than the general population. Now researchers have measured how much firefighters‘ exposure to carcinogens and other harmful compounds increases when fighting fires. Their study also points to one possible way to reduce that exposure. (Mehr in: Cancer News — ScienceDaily)

- Read more

Machine learning identifies breast lesions likely to become cancer

18. Okt. 2017

A machine learning tool can help identify which high-risk breast lesions are likely to become cancerous, according to a new study. Researchers said the technology has the potential to reduce unnecessary surgeries. (Mehr in: Cancer News — ScienceDaily)

- Read more

Therapeutic form of arsenic is a potential treatment for deadly type of brain cancer

17. Okt. 2017

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element may be a potent force against cancer. (Mehr in: Cancer News — ScienceDaily)

- Read more

Veranstaltungen

1st Gießen Symposium of Insect Biotechnology

01. Okt. 2017

We are delighted to invite delegates to the 1st Gießen Symposium for Insect Biotechnology. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

19th Herbstakademie

01. Okt. 2017

Embodied Aesthetics: Resonance in Perception, Expression and Therapy (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

17. Wissenschaftliche Jahrestagung der DGSF

01. Okt. 2017

Von der Neutralität zur Parteilichkeit – SystemikerInnen mischen sich ein (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

16. Deutscher Kongress für Versorgungsforschung

01. Okt. 2017

Unter dem Thema: „Zukunft Regionale Versorgung – Forschung, Innovation, Kooperation“ wird vom 4. bis 6. Oktober 2017 der 16. Deutsche Kongress für Versorgungsforschung (DKVF2016) in der Urania in Berlin stattfinden. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

100 Jahre Zukunft. Die Mistel in der Krebstherapie

01. Okt. 2017

Die Misteltherapie – immer noch umstritten oder längst etabliert? Antworten auf diese Frage gibt es beim Symposium „100 Jahre Zukunft. Die Mistel in der Krebstherapie“ am 21. Oktober 2017 in Berlin. Das Symposium richtet sich an Ärzte, Pharmazeuten, Therapeuten, Pflegende und Patienten. Theorie und Praxis kommen gleichermaßen zu Wort: Best-Practice, Erfahrungen und spannende Forschungsergebnisse werden vorgestellt. Diskussionen und Roundtables ergänzen das Programm. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

100 Jahre Max-Planck-Institut für Physik – Jubiläumssymposium und Festakt

01. Okt. 2017

Das Max-Planck-Institut für Physik begeht seinen 100. Jahrestag: Am 1. Oktober 1917 nahm das damalige Kaiser-Wilhelm-Institut für Physik unter Direktor Albert Einstein seine Arbeit auf. Dieses Jubiläum feiert das MPI für Physik mit einem wissenschaftlichen Symposium, das vom 10. bis 12. Oktober 2017 stattfindet. Ein anschließender Festakt mit Abendprogramm beschließt die Feierlichkeiten zum 100-jährigen Bestehen des Instituts. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

22. International Biohydrometallurgy Symposium

01. Sep. 2017

Call for Papers is open – submit your contribution until 10 January 2017

The biannual International Biohydrometallurgy Symposium is the global forum for experts from academia and industry active in the fields of biomining, bioleaching and bioremediation. These technologies have a high potential to establish environmentally favourable processes for the recovery of primary and secondary precious and base metal resources as well as the remediation of exploited mining sites. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen