Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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New genetic compound marker could help early diagnosis of aggressive prostate cancer

A research team has discovered a link between the interplay of certain simultaneously occurring genetic changes in the HOXB13 and CIP2A genes, aggressiveness of prostate cancer, high risk of developing the disease, and poorer survival rates of patients. Prostate cancer is a major challenge in health care with over one million new cases and 300,000 deaths from it each year worldwide. (Mehr in: Cancer News — ScienceDaily)

Experts advise against routine testing for prostate cancer

Routine testing for prostate cancer is not recommended for most men because the benefit is small and uncertain and there are clear harms, say experts in a new article. (Mehr in: Cancer News — ScienceDaily)

Hormone therapy can make prostate cancer worse, study finds

Scientists have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing the cancer to spread. Their findings also point to a simple blood test that may help doctors predict when this type of hormone therapy resistance will occur. (Mehr in: Cancer News — ScienceDaily)

New genetic marker could help diagnose aggressive prostate cancer

A new link has been found between certain genetic mutations, the aggressiveness of prostate cancer, risk of developing the disease and poorer survival rates of patients. (Mehr in: Cancer News — ScienceDaily)

Nuclear gatekeeper could block undruggable prostate cancer targets

Blocking nuclear gateways that traffic cancer-promoting molecules to nucleus, could offer a new way to target aggressive cancer. (Mehr in: Cancer News — ScienceDaily)

Common skin cancer can signal increased risk of other cancers

People who develop abnormally frequent cases of a skin cancer known as basal cell carcinoma appear to be at significantly increased risk for the development of other cancers, including blood, breast, colon and prostate cancers, according to a preliminary study. (Mehr in: Cancer News — ScienceDaily)

Low-protein diet during pregnancy increases prostate cancer risk in offspring, rat study shows

Experiments with rats show that intrauterine protein restriction induces sex hormone imbalance, which appears to favor development of cancer in old age. The rate of prostate tumor development reached 50 percent among the old rats submitted to low-protein diet during pregnancy and lactation alike. (Mehr in: Cancer News — ScienceDaily)

Blood test can predict optimal treatment for advanced prostate cancer, study finds

Scientists have demonstrated that a blood test can predict how patients with advanced prostate cancer will respond to specific treatments, leading to improved survival. (Mehr in: Cancer News — ScienceDaily)

The cause of prostate cancer progression to incurable stage has likely been uncovered

Researchers have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism (SNP) rs11672691 influences prostate cancer aggressiveness. Their findings also suggest ways to improve risk stratification and clinical treatment for advanced prostate cancer. (Mehr in: Cancer News — ScienceDaily)

RNA molecules that regulate action of male hormone in prostate cancer identified

A study detected in tumoral tissue hundreds of RNAs that do not encode proteins but appear to regulate effects of androgens and androgen receptors on gene expression in tumors. By investigating the connection between the presence of these molecules and tumor aggressiveness, the research paves the way for new scientific approaches focusing on the transcription process of noncoding RNA. (Mehr in: Cancer News — ScienceDaily)

Cancer news

Tweaking cells‘ gatekeepers could lead to new way to fight cancer

19. Sep. 2018

Researchers have devised a way to manipulate numbers of individual nuclear pores — a breakthrough that may one day stop cancerous cells from proliferating out of control. (Mehr in: Cancer News — ScienceDaily)

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New hurdle for developing immunotherapies

18. Sep. 2018

A new discovery tosses a new wrench into the process of building better molecules to develop immunotherapies. (Mehr in: Cancer News — ScienceDaily)

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Eating foods with low nutritional quality ratings linked to cancer risk in large European cohort

18. Sep. 2018

The consumption of foods with higher scores on the British Food Standards Agency nutrient profiling system (FSAm-NPS), reflecting a lower nutritional quality, is associated with an increased risk of developing cancer. (Mehr in: Cancer News — ScienceDaily)

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How cells repurpose their garbage disposal systems to promote inflammation

18. Sep. 2018

Researchers have unraveled new insights into the way cells leverage G-protein-coupled receptors (GPCRs) and their cellular waste disposal systems to control inflammation. The findings suggest some existing cancer drugs that inhibit these cellular activities might be repurposed to treat vascular inflammation, which occurs when artery-blocking plaques form in atherosclerosis. (Mehr in: Cancer News — ScienceDaily)

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CRISPR screen reveals new targets in more than half of all squamous cell carcinomas

18. Sep. 2018

Researchers sheds light on p63 activity in squamous cell carcinoma of the lung, providing an actionable path forward to drug development against this known cause of cancer. (Mehr in: Cancer News — ScienceDaily)

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Chemists create circular fluorescent dyes for biological imaging

18. Sep. 2018

Chemists have created a new class of fluorescent dyes that function in water and emit colors based solely on the diameter of circular nanotubes made of carbon and hydrogen. (Mehr in: Cancer News — ScienceDaily)

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Colon cancer is caused by bacteria and cell stress

18. Sep. 2018

Scientists have made an unexpected discovery while investigating the triggering factors of colon cancer: Cell stress in combination with an altered microbiota in the colon drives tumor growth. Previously, it was assumed that this combination only contributes to inflammatory intestinal diseases. (Mehr in: Cancer News — ScienceDaily)

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Better chemo drug adsorption onto targeted delivery capsules

18. Sep. 2018

One of the challenges in cancer research is improving the delivery of chemo drugs to enhance their efficacy while decreasing the risk of side effects. Scientists now perform a theoretical prediction of adsorption of a well-known chemo drug onto active carbon with aluminium inclusions, to show its potential as an oral chemotherapy delivery capsule. (Mehr in: Cancer News — ScienceDaily)

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Zika vaccine shows promise for treating deadly brain cancer

18. Sep. 2018

Researchers have successfully deployed a Zika virus vaccine to target and kill human glioblastoma brain cancer stem cells, which had been transplanted into mice. In a new study, the team shows that a live, attenuated version of the Zika virus could form the basis of a new treatment option for this fatal brain cancer. (Mehr in: Cancer News — ScienceDaily)

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Silicone breast implants linked to increased risk of some rare harms

18. Sep. 2018

Women receiving silicone breast implants may be at increased risk of several rare adverse outcomes compared to the general population. (Mehr in: Cancer News — ScienceDaily)

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Artificial intelligence can determine lung cancer type

17. Sep. 2018

A new computer program can analyze images of patients‘ lung tumors, specify cancer types, and even identify altered genes driving abnormal cell growth, a new study shows. (Mehr in: Cancer News — ScienceDaily)

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Developmental stage for No. 1 eye tumor in children

17. Sep. 2018

Investigators have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the door for future interventions in retinoblastoma (RB), a tumor of the retina that affects children under five years of age. (Mehr in: Cancer News — ScienceDaily)

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New blood test detects early stage pancreatic cancer

17. Sep. 2018

Pancreatic cancer is currently very difficult to detect while it is still resectable. A new blood test can detect pancreatic cancer in the very earliest stages of the disease. (Mehr in: Cancer News — ScienceDaily)

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Daily low-dose aspirin found to have no effect on healthy life span in older people

16. Sep. 2018

In a clinical trial to determine the effects of daily low-dose aspirin in healthy older adults without previous cardiovascular events, aspirin did not prolong healthy, independent living free of dementia or physical disability. (Mehr in: Cancer News — ScienceDaily)

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Research in yeast leads to serendipitous finding about a central nervous system disorder

14. Sep. 2018

Researchers found that an important quality control mechanism in baker’s yeast is closely connected to hypomyelinating leukodystrophy, a debilitating disease found in children. The findings could indicate a therapeutic approach for this rare disease, as well as for multiple sclerosis and other neurodegenerative diseases. (Mehr in: Cancer News — ScienceDaily)

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New method promises fewer side effects from cancer drugs

14. Sep. 2018

A recent achievement in the field of protein research allows for better tailored pharmaceuticals with fewer side effects. (Mehr in: Cancer News — ScienceDaily)

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Cancer drug and antidepressants provide clues for treating brain-eating amoeba infections

13. Sep. 2018

Researchers have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the US Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen and antidepressant Prozac. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

11. Bundesalgenstammtisch 2018; Mikroalgen für Umwelt und Wertschöpfung

01. Sep. 2018

Der jährlich stattfindende „Bundesalgenstammtisch“ ist die deutschsprachige Kommunikationsplattform für alle, die mit der Algenbiotechnologie in Wissenschaft und Industrie befasst sind. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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4. Tag der Arbeitsmedizin in Hannover

01. Sep. 2018

Dialogforen Arbeitsmedizin und Arbeitssicherheit – Eine Veranstaltungsreihe für Wissenschaft und Praxis der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V. (DGAUM) und RG GmbH (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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3rd European Conference on Natural Products

01. Sep. 2018

The 3rd European Conference on Natural Products will again feature recent advances in secondary metabolite research. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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18. Wissenschaftliche Jahrestagung der DGSF

01. Sep. 2018

Ich, Du und die anderen … Selbstorganisation – Selbststeuerung und die Frage nach dem Sinn

18. Wissenschaftliche Jahrestagung der DGSF vom 20.- 22. September 2018 an der Universität Oldenburg (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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18. Scientific Meeting (ScieM)

01. Sep. 2018

Am 27. und 28. September 2018 findet das 18. Scientific Meeting (ScieM) des Mukoviszidose e.V. in Bad Salzschlirf statt. Thema des diesjährigen Meetings sind „Anti-inflammatorische Therapien im Kontext des Mikrobioms in Lunge und Darm“. Mukoviszidose-Forscherinnen und -Forscher aus der ganzen Welt sind dazu eingeladen, beim Meeting über dieses zurzeit sehr relevante Forschungsthema zu diskutieren. Abstracts für Vorträge können bis zum 15. Juni 2018 eingereicht werden. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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17. Tag der Arbeitsmedizin in Berlin

01. Sep. 2018

Dialogforen Arbeitsmedizin und Arbeitssicherheit – Eine Veranstaltungsreihe für Wissenschaft und Praxis der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V. (DGAUM) und RG GmbH (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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17. Jahrestagung der CURAC auf dem Leipziger Medizincampus

01. Sep. 2018

Vom 13.-15.09.2018 findet auf dem Medizincampus Leipzig die 17. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie (CURAC) statt. Sie ist das zentrale deutschsprachige Forum für technische Entwicklungen und klinische Anwendungen im Bereich informationsgestützte Chirurgie. Erwartet werden ca. 150 AnwenderInnen und EntwicklerInnen zum fachlichen Austausch. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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