Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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How pancreatic tumors lead to weight loss

A study offers insight into the weight loss seen in pancreatic cancer patients, and suggests that weight loss may not necessarily affect patients‘ survival. (Mehr in: Cancer News — ScienceDaily)

New drugs could also be deployed against lung and pancreatic cancers

A new anti-cancer drug may be effective against a wider range of cancers than previously thought. Using a mouse model and samples taken from cancer patients, a team from the Technical University of Munich (TUM) has shown that a new class of drugs known as SHP2 inhibitors is also effective against aggressive, hard-to-treat tumors such as lung and pancreatic cancers. Clinical trials currently underway had previously excluded patients with these cancers. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

A way to prevent pancreatic cancer from spreading post-surgery?

New research suggests a strategy for lowering the odds of metastasis following successful pancreatic cancer surgery: The post-operative period, suggests a researcher, ‚offers a window during which efforts might be made to keep cortisol levels down and T cells strong so the patient’s own immune system can kill the cancer cells that have made their way to other parts of the body but until this point have been dormant.‘ (Mehr in: Cancer News — ScienceDaily)

Novel theranostic approach for treating pancreatic cancer patients shows promise

German researchers have developed a novel diagnostic and therapeutic (theranostic) procedure for patients with ductal pancreatic adenocarcinoma, a deadly cancer with an extremely poor prognosis (five-year survival rate of less than 5 percent) and limited treatment options. (Mehr in: Cancer News — ScienceDaily)

Injecting gene cocktail into mouse pancreas leads to human-like tumors

A researcher has invented a unique method to generate, in mice, pancreatic tumors that resemble human pancreatic cancer. This will be a tool researchers can use to develop new drugs that extend patients‘ lives, and it is a tool researchers have not had at their disposal before. (Mehr in: Cancer News — ScienceDaily)

The connection between diet, obesity, and cancer: Nutrition experts explore the evidence

About one third of cancer cases are estimated to be linked to dietary and other modifiable risk factors, especially for obesity-related cancers such as breast, colorectal, ovarian, endometrial, kidney, gallbladder, esophageal, and pancreatic cancers. (Mehr in: Cancer News — ScienceDaily)

Gut bacteria determine speed of tumor growth in pancreatic cancer

The population of bacteria in the pancreas increases more than a thousand fold in patients with pancreatic cancer, and becomes dominated by species that prevent the immune system from attacking tumor cells. (Mehr in: Cancer News — ScienceDaily)

Improved method of treating pancreatic cancer

A heating and freezing process known as dual thermal ablation can kill pancreatic cancer cells, according to new research. (Mehr in: Cancer News — ScienceDaily)

Researchers discover a potential new therapeutic strategy for pancreatic cancer

In most pancreatic cancer patients, the diagnosis is made when the disease is already advanced, and there is no effective treatment at present. There have been no significant advances to combat it in recent decades and unfortunately, its occurrence is on the increase. Now, a group of researchers may have found a new form of attack. (Mehr in: Cancer News — ScienceDaily)

Pancreatic cancer: Gene duplication explains tumor aggressiveness

Pancreatic cancer is a form of cancer associated with the highest mortality rates in the world. Genetic changes that could explain his aggressiveness and early metastasis had not been found yet. A team has now shown that those characteristics can be explained by specific gene amplifications which occur along various evolutionary pathways of the cancer. Based on this discovery, they have derived basic principles underlying the biology of pancreatic cancer. (Mehr in: Cancer News — ScienceDaily)

Cancer news

New drug halves hearing loss in children following cancer treatment

20. Jun. 2018

Giving the drug sodium thiosulphate after chemotherapy reduces hearing loss in children treated for liver cancer, according to new findings. (Mehr in: Cancer News — ScienceDaily)

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Competition for space: Oncogenic mutant cells vs normal cells

20. Jun. 2018

Researchers discovered how oncogenic mutant cells selectively expand into surrounding normal tissues and occupy them based on prediction by computer simulation and experimental verification. (Mehr in: Cancer News — ScienceDaily)

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How pancreatic tumors lead to weight loss

20. Jun. 2018

A study offers insight into the weight loss seen in pancreatic cancer patients, and suggests that weight loss may not necessarily affect patients‘ survival. (Mehr in: Cancer News — ScienceDaily)

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Towards personalised medicine: One type of data is not enough

20. Jun. 2018

To understand the biology of diseased organs researchers can use different types of molecular data. One of the biggest computational challenges at the moment is integrating these multiple data types. A new computational method jointly analyses different types of molecular data and disentangles the sources of disease variability to guide personalised treatment. (Mehr in: Cancer News — ScienceDaily)

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New therapeutic opportunity for the treatment of resistant malignant melanoma

20. Jun. 2018

Researchers have revealed that malignant melanoma can reprogram their protein synthesis machinery and become addicted to a new family of enzymes that modify transfer RNAs during acquired resistance. The inhibition of these molecules synergies with targeted therapies to produce a strong anti-tumoral effect. These new findings will be key in the development of improved diagnostic tools and melanoma treatment. (Mehr in: Cancer News — ScienceDaily)

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Rare in-vivo study shows weak brain nodes have strong influence on memory network

20. Jun. 2018

The majority of existing simulation studies show that the parts of the brain with high connectivity, the so-called ‚hubs‘, are most important when it comes to several different cognitive tasks. But the results of a rare in-vivo study demonstrates that the nucleus accumbens (NAc) — a part of the brain with weak connections — plays an unexpectedly influential role in enhancing the memory network. (Mehr in: Cancer News — ScienceDaily)

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New tissue-imaging technology could enable real-time diagnostics, map cancer progression

20. Jun. 2018

A new microscope system can image living tissue in real time and in molecular detail, without any chemicals or dyes. It enables researchers to study concurrent processes within cells and tissue, and could give cancer researchers a new tool for tracking tumor progression and physicians new technology for tissue pathology and diagnostics. (Mehr in: Cancer News — ScienceDaily)

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Putting the brakes on metastatic cancer

20. Jun. 2018

A groundbreaking discovery has identified previously unknown therapeutic targets that could be key to preventing the spread of cancer. Researchers found that by inhibiting several newly identified gene targets they could block more than 99.5 per cent of cancer metastasis in living cells. (Mehr in: Cancer News — ScienceDaily)

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Long-term estrogen therapy changes microbial activity in the gut

19. Jun. 2018

Long-term therapy with estrogen and bazedoxifene alters the microbial composition and activity in the gut, affecting how estrogen is metabolized, a new study in mice found. (Mehr in: Cancer News — ScienceDaily)

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The answer to triple-negative breast cancer?

19. Jun. 2018

Researchers have developed a computer program which has revealed a previously unknown combination of drugs that may be the answer to Triple Negative Breast Cancer (TNBC), using genetic and treatment data from TNBC cells grown in labs and from hundreds of patients world-wide. Importantly researchers can tell, by inputting patients‘ genomic and proteomic information into their computer model, who may benefit from this drug combination or not — saving precious time. (Mehr in: Cancer News — ScienceDaily)

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Breast cancer could be prevented by targeting epigenetic proteins, study suggests

19. Jun. 2018

Researchers have discovered that epigenetic proteins promote the proliferation of mammary gland stem cells in response to the sex hormone progesterone. The study suggests that inhibiting these proteins with drugs could prevent the development of breast cancer in women at high risk of the disease. (Mehr in: Cancer News — ScienceDaily)

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The force is strong within us: New study explores cell mechanics at work

19. Jun. 2018

A research team focused on measuring the stiffness, bending, twisting and viscosity of individual cells — focused on a breast cancer cell line — using all of the most state-of-the art technology at their disposal. How both healthy and cancerous cells respond to this environment — and whether there are key differences that can be identified for future diagnostic applications was of keen interest to the researchers. (Mehr in: Cancer News — ScienceDaily)

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Targeting the engine room of the cancer cell

18. Jun. 2018

Researchers have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug combinations that are most likely to kill them. (Mehr in: Cancer News — ScienceDaily)

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Electrical wire properties of DNA linked to cancer

18. Jun. 2018

New research finds a connection between a cancer mutation and electron-mediated DNA repair. (Mehr in: Cancer News — ScienceDaily)

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Novel combination as potential therapy for high-risk neuroblastoma

18. Jun. 2018

Researchers at VCU Massey Cancer Center in Richmond, Virginia, have identified a promising target to reverse the development of high-risk neuroblastoma and potentially inform the creation of novel combination therapies for the disease. (Mehr in: Cancer News — ScienceDaily)

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Laser-sonic scanner aims to replace mammograms for finding breast cancer

18. Jun. 2018

For women over 40, mammography is a necessary yet annoying procedure to endure every year or two. The technique, while valuable for reducing breast cancer deaths, is less than ideal because it exposes patients to X-ray radiation and requires their breasts to be painfully squished between plates. The plates flatten the breast so the X-rays can more easily pass through it and produce a clear image. (Mehr in: Cancer News — ScienceDaily)

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Genomics offers new treatment options for infants with range of soft tissue tumors

18. Jun. 2018

The genetic causes of a group of related infant cancers have been discovered by scientists. Whole genome sequencing of tumours revealed mutations which are targetable by existing drugs used to treat lung cancer and melanoma. The results have implications for clinical practice and the diagnosis of rare cancers in infants, and could lead to new, targeted treatment options for these children. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

10. Stuttgarter Lasertage

01. Jun. 2018

Highlights und Innovationen aus der industriellen Anwendung der Lasertechnik stehen im Mittelpunkt der 10. Stuttgarter Lasertage (SLT 2018), die am 5. und 6. Juni 2018 parallel zur Fachmesse LASYS im Internationalen Congress Center Stuttgart (ICS) stattfinden. Veranstalter sind das Institut für Strahlwerkzeuge (IFSW) der Universität Stuttgart und die Messe Stuttgart. Erwartet werden rund 350 Besucher. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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24. Jahrestagung der Deutschen Gesellschaft für Radioonkologie e. V.

01. Jun. 2018

Das wissenschaftliche Programm ist online einsehbar unter http://degro-jahrestagung.de/programm/wissenschaftliches-programm (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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1. World Café 2018 des DGBMT Fachausschusses Usability

01. Jun. 2018

Der DGBMT Fachausschuss Usability befasst sich mit allen Aspekten der Gebrauchstauglichkeit und User Experience in Zusammenhang mit Medizintechnik. Regelmäßig entscheidet der Fachausschuss dabei über neue Schwerpunkte für die kommenden Jahre. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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17. Tag der Arbeitsmedizin in Hamburg

01. Jun. 2018

Dialogforen Arbeitsmedizin und Arbeitssicherheit – Eine Veranstaltungsreihe für Wissenschaft und Praxis von DGAUM und RG GmbH (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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15th International Conference on Inorganic Membranes

01. Jun. 2018

The International Conference on Inorganic Membranes (ICIM) is held every second year all over the world in rotation. This series of conferences has been established as a global high-level event on inorganic membranes and innovations. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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15. Kongress Qualitätssicherung in der medizinischen Begutachtung

01. Jun. 2018

Am 9. Juni 2018 werden sich zum 15. Mal Medizinische Sachverständige, Juristen und Sachbearbeiter aus Verwaltung und Versicherungswirtschaft treffen, um interdisziplinär über Qualitätssicherungsmaßnahmen in der medizinischen Begutachtung zu diskutieren. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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15. HepNet Symposium der Deutschen Leberstiftung

01. Jun. 2018

Akkreditiert: mit 10 CME-Punkten von der Ärztekammer Niedersachsen mit 5 iCME-Punkten von der Akademie für Infektionsmedizin

Wissenschaftliche Leitung: Prof. Dr. med. Michael P. Manns, Hannover Prof. Dr. med. Stefan Zeuzem, Frankfurt Prof. Dr. med. Claus Niederau, Oberhausen Prof. Dr. med. Ulrike Protzer, München Prof. Dr. med. Peter Schirmacher, Heidelberg

Veranstalter: Deutsche Leberstiftung

Ort: Medizinische Hochschule Hannover, Gebäude J02, Hörsaal D (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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