Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Yeast spotlights genetic variation’s link to drug resistance

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists show that high genetic diversity can prime new mutations that cause drug resistance. The study has implications for our understanding of the evolution of resistance to antimicrobial and anticancer drugs. (Mehr in: Cancer News — ScienceDaily)

Cause of cancer form in the liver identified

Researchers have identified the two genes whose mutation cause a serious cancer form found in the liver. The result sets concrete goals for future treatment of the otherwise incurable disease. (Mehr in: Cancer News — ScienceDaily)

New drug hope for rare bone cancer patients

Patients with a rare bone cancer of the skull and spine — chordoma — could be helped by existing drugs, suggest scientists. In the largest genomics study of chordoma to date, scientists show that a group of chordoma patients have mutations in genes that are the target of existing drugs, known as PI3K inhibitors. (Mehr in: Cancer News — ScienceDaily)

Kein Sex ist auch eine Lösung

Sexuelle Fortpflanzung sorgt unter anderem dafür, dass sich schädliche Mutationen nicht so stark ansammeln. Bei manchen Tierarten, wie zum Beispiel einigen Hornmilbenarten, ging Sex jedoch im Laufe der Evolution verloren und die asexuelle Fortpflanzung durch Klone setzte sich durch. Bisher war es wissenschaftlicher Konsens, dass der Wechsel zu einer schrittweisen Ansammlung schädlicher Mutationen führt und das Aussterben der Art nach sich zieht. Nun haben Forscher der Universitäten Göttingen und Lausanne herausgefunden, dass es bei Hornmilben anders ist. Wenn sie sehr lange asexuell sind, können sie schädliche Mutationen besser loswerden als ihre Verwandten, die sich sexuell fortpflanzen. (Mehr in: Pressemitteilungen – […]

No sex, no problem!

Sexual reproduction is linked to various benefits for the survival of a species. Amongst others, sex counters the accumulation of accidentally occurring deleterious mutations by allowing for exchange of genetic material. According to the scientific consensus, loss of sex in favour of clonal reproduction leads to a stepwise accumulation of deleterious mutations, which eventually causes extinction of a species. Now scientists of the Universities of Göttingen and Lausanne found out, that ancient asexual oribatid mites are more effective in purging deleterious mutations as compared to their sexual relatives. The results are reported in the current issue of Nature Communications. (Mehr […]

A new genetic marker accounts for up to 1.4 percent of cases of hereditary colon cancer

Scientists have identified a new genetic marker that accounts for up to 1.4 percent of cases of hereditary colon cancer. Patients with mutations in this gene, if identified, could follow a clinical approach much more consistent with their genetics. (Mehr in: Cancer News — ScienceDaily)

A mutation supercharges tumor-suppressor

Stanford scientists have found an answer to one of cancer biology’s toughest and most important questions: how does the body suppress tumors? (Mehr in: Cancer News — ScienceDaily)

Epilepsie in Zukunft altersgruppenspezifisch behandelbar – erkrankte Säuglinge profitieren

Mutationen in einem bestimmten Gen können eine Epilepsie auslösen. Wissenschaftler am Hertie-Institut für klinische Hirnforschung (HIH) in Tübingen haben vor Kurzem herausgefunden, dass die Art der Mutation ganz wesentlich ist für die Behandlung von Patienten. Profitieren können von den Forschungsergebnissen vor allem Säuglinge, die an epileptischen Anfällen leiden und nun gezielter behandelt werden können. Die Gemeinnützige Hertie-Stiftung engagiert sich mit einem Volumen von durchschnittlich neun Millionen Euro im Jahr in der Förderung der Hirnforschung und unterstützt dabei unter anderem den Bereich Neurologie mit Schwerpunkt Epileptologie am HIH. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

BRCA1: Mystery of breast cancer risk gene solved, 20 years after its discovery

More than 20 years after scientists revealed that mutations in the BRCA1 gene predispose women to breast cancer, scientists have pinpointed the molecular mechanism that allows those mutations to wreak their havoc. (Mehr in: Cancer News — ScienceDaily)

Genetic test successfully detects some asymptomatic pancreatic cancers

PancreaSeq® analyzed mutations known to be associated with precursors to pancreatic cancers, report investigators at the conclusion of a study. (Mehr in: Cancer News — ScienceDaily)

Cancer news

New findings explain how UV rays trigger skin cancer

18. Okt. 2017

Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the US in 2017, according to the Centers for Disease Control and Prevention. A fraction of those melanomas come from pre-existing moles, but the majority of them come from sources unknown — until now. (Mehr in: Cancer News — ScienceDaily)

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Researchers release the brakes on the immune system

18. Okt. 2017

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural “brakes” in the immune defense mechanism, which normally prevent an excessive immune response. Researchers have now been able to take off one of these brakes. The study could pave the way for more effective cancer therapies, they say. (Mehr in: Cancer News — ScienceDaily)

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Yeast spotlights genetic variation’s link to drug resistance

18. Okt. 2017

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists show that high genetic diversity can prime new mutations that cause drug resistance. The study has implications for our understanding of the evolution of resistance to antimicrobial and anticancer drugs. (Mehr in: Cancer News — ScienceDaily)

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Battling flames increases firefighters‘ exposure to carcinogens

18. Okt. 2017

The threat of getting burned by roaring flames is an obvious danger of firefighting, but other health risks are more subtle. For example, firefighters have been found to develop cancer at higher rates than the general population. Now researchers have measured how much firefighters‘ exposure to carcinogens and other harmful compounds increases when fighting fires. Their study also points to one possible way to reduce that exposure. (Mehr in: Cancer News — ScienceDaily)

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Machine learning identifies breast lesions likely to become cancer

18. Okt. 2017

A machine learning tool can help identify which high-risk breast lesions are likely to become cancerous, according to a new study. Researchers said the technology has the potential to reduce unnecessary surgeries. (Mehr in: Cancer News — ScienceDaily)

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Therapeutic form of arsenic is a potential treatment for deadly type of brain cancer

17. Okt. 2017

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element may be a potent force against cancer. (Mehr in: Cancer News — ScienceDaily)

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Cancer: New compound targets energy generation, thereby killing metastatic cells

17. Okt. 2017

Researchers have identified an enzyme that supports the survival and dissemination of metastatic cells, and developed a synthetic compound that targets the enzyme and kills the metastatic cells in mice with cancer. (Mehr in: Cancer News — ScienceDaily)

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Timing of melanoma diagnosis, treatment critical to survival

17. Okt. 2017

A new study underscores the importance of early detection and treatment of melanoma, the deadliest form of skin cancer. The research indicates that the sooner patients were treated, the better their survival, particularly for stage I melanoma. (Mehr in: Cancer News — ScienceDaily)

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Many pelvic tumors in women may have common origin: Fallopian tubes

17. Okt. 2017

Most, and possibly all, ovarian cancers start, not in ovaries, but instead in the fallopian tubes attached to them, report investigators. (Mehr in: Cancer News — ScienceDaily)

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Novel mechanism of resistance to anti-cancer drugs

17. Okt. 2017

Investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings suggest a strategy for overcoming this resistance. (Mehr in: Cancer News — ScienceDaily)

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Biology of childhood brain tumor subtypes offers clues to precision treatments

17. Okt. 2017

Researchers investigating pediatric low-grade gliomas (PLGG), the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer. By shedding light on subtle distinctions in tumor biology, these findings offer clues to designing more effective anticancer treatments to precisely target tumors in individual patients. (Mehr in: Cancer News — ScienceDaily)

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Bolstering fat cells offers potential new leukemia treatment

16. Okt. 2017

Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, says a new study. Researchers found that boosting adipocytes, or fat cells, located in the bone morrow suppressed cancerous leukemia cells but — in a surprise to the research team — also induced the regeneration of healthy blood cells. (Mehr in: Cancer News — ScienceDaily)

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Scientists identify biomarker for progression, drug response in brain cancer

16. Okt. 2017

Scientists have reported results from a glioblastoma study in which they validated a biomarker indicative of a patient’s prognosis and likely response to specific therapies. (Mehr in: Cancer News — ScienceDaily)

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Scientists demonstrate path to linking the genome to healthy tissues, disease

16. Okt. 2017

A study has reached a major milestone in establishing a baseline understanding of gene expression across healthy human tissues, and linking genes to disease. (Mehr in: Cancer News — ScienceDaily)

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Scientists reveal the relationship between sugar, cancer

13. Okt. 2017

A nine-year joint research project has led to a crucial breakthrough in cancer research. Scientists have clarified how the Warburg effect, a phenomenon in which cancer cells rapidly break down sugars, stimulates tumor growth. This discovery provides evidence for a positive correlation between sugar and cancer, which may have far-reaching impacts on tailor-made diets for cancer patients. (Mehr in: Cancer News — ScienceDaily)

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Liquid biopsy for retinoblastoma

12. Okt. 2017

A new study provides proof of concept for a safe and effective way to derive genetic information from a retinoblastoma tumor. (Mehr in: Cancer News — ScienceDaily)

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3D packaging of DNA regulates cell identity

12. Okt. 2017

The ability of a stem cell to differentiate into cardiac muscle (and by extension other cell types) depends on what portions of the genome are available for activation, which is controlled by the location of DNA in a cell’s nucleus, new research suggests. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

1st Gießen Symposium of Insect Biotechnology

01. Okt. 2017

We are delighted to invite delegates to the 1st Gießen Symposium for Insect Biotechnology. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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19th Herbstakademie

01. Okt. 2017

Embodied Aesthetics: Resonance in Perception, Expression and Therapy (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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17. Wissenschaftliche Jahrestagung der DGSF

01. Okt. 2017

Von der Neutralität zur Parteilichkeit – SystemikerInnen mischen sich ein (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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16. Deutscher Kongress für Versorgungsforschung

01. Okt. 2017

Unter dem Thema: „Zukunft Regionale Versorgung – Forschung, Innovation, Kooperation“ wird vom 4. bis 6. Oktober 2017 der 16. Deutsche Kongress für Versorgungsforschung (DKVF2016) in der Urania in Berlin stattfinden. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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100 Jahre Zukunft. Die Mistel in der Krebstherapie

01. Okt. 2017

Die Misteltherapie – immer noch umstritten oder längst etabliert? Antworten auf diese Frage gibt es beim Symposium „100 Jahre Zukunft. Die Mistel in der Krebstherapie“ am 21. Oktober 2017 in Berlin. Das Symposium richtet sich an Ärzte, Pharmazeuten, Therapeuten, Pflegende und Patienten. Theorie und Praxis kommen gleichermaßen zu Wort: Best-Practice, Erfahrungen und spannende Forschungsergebnisse werden vorgestellt. Diskussionen und Roundtables ergänzen das Programm. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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100 Jahre Max-Planck-Institut für Physik – Jubiläumssymposium und Festakt

01. Okt. 2017

Das Max-Planck-Institut für Physik begeht seinen 100. Jahrestag: Am 1. Oktober 1917 nahm das damalige Kaiser-Wilhelm-Institut für Physik unter Direktor Albert Einstein seine Arbeit auf. Dieses Jubiläum feiert das MPI für Physik mit einem wissenschaftlichen Symposium, das vom 10. bis 12. Oktober 2017 stattfindet. Ein anschließender Festakt mit Abendprogramm beschließt die Feierlichkeiten zum 100-jährigen Bestehen des Instituts. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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13. Kölner Abend der Sportwissenschaft mit Wolf-Dieter Poschmann

01. Sep. 2017

Die Deutsche Sporthochschule Köln und die Gesellschaft der Freunde und Förderer laden Sie herzlich zum 13. Kölner Abend der Sportwissenschaft am 20. September 2017 (Hörsaal 1 der DSHS Köln, 19:00 Uhr) zu folgendem Thema ein:

Denksport – Aktiv gegen das Vergessen! (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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