A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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10 years Bionics Center at TUM: Technical Innovations Based on Nature

The “Leonardo da Vinci Center for Bionics” was established over a decade ago at the Technical University of Munich (TUM). Since then, the cross-faculty research platform has been promoting the technical development of operating principles that nature concocted in the evolutionary process: The creative potential in the “Test Laboratory of Nature” is translated into technical solutions. For example, the Multi-Arm Snake-Like Manipulator-System was developed at the Department of Microtechnology and an intelligent building shell arose in the architectural department. The new head of the Bionics Center is now Professor Harald Luksch. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

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10 Jahre Bionik-Zentrum an der TUM: Technische Innovationen nach dem Vorbild der Natur

Seit einem Jahrzehnt gibt es das „Leonardo da Vinci-Zentrum für Bionik“ an der Technischen Universität München (TUM). Die fakultätsübergreifende Forschungsplattform fördert die technische Fortentwicklung von Prinzipien, die sich die Natur im Evolutionsprozess zurechtgelegt hat: Das Kreativpotential im „Testlabor Natur“ wird übersetzt in technische Lösungen. Entwickelt wurde beispielsweise das Multi-Arm-Snake-Like-Manipulatorsystem am Lehrstuhl für Mikrotechnik und eine intelligente Gebäudehülle entstand in der Architektur. Neuer Leiter des Bionik-Zentrums ist nun Professor Harald Luksch. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Nevita erhält Innovations- und Entrepreneurpreis 2017 der Gesellschaft für Informatik

Brandenburg/Havel 05. Oktober 2017 Im Rahmen der INFORMATIK 2017 vom 25.-29.09.2017 in Chemnitz wurde das Projekt „Nevita“ der Technischen Hochschule Brandenburg (THB) von Prof. Dr. Andreas Oberweis, Vize-Präsident der Gesellschaft für Informatik e.V. (GI), mit dem Innovations- und Entrepreneurpreis der GI ausgezeichnet. Das durch ein EXIST-Gründerstipendium unterstützte medizininformatische Projekt Nevita steht für den innovativen Einsatz von Informatik in der medizinischen Versorgung in Entwicklungs- und Schwellenländern. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

16. Deutscher Kongress für Versorgungsforschung

Unter dem Thema: „Zukunft Regionale Versorgung – Forschung, Innovation, Kooperation“ wird vom 4. bis 6. Oktober 2017 der 16. Deutsche Kongress für Versorgungsforschung (DKVF2016) in der Urania in Berlin stattfinden. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

Professor Dr. Elmar Wienecke erhält Innovationspreis der Stiftung für Gesundheit und Umwelt (SfGU)

Professor Dr. Elmar Wienecke wurde im Rahmen des Internationalen Bodenseekongresses von der Stiftung Gesundheit und Umwelt (SfGU) für seine herausragende Forschungs- und Entwicklungsarbeit und deren praktische Anwendung im Bereich der Mikronährstofftherapie mit dem Innovationspreis gewürdigt. Die Auszeichnung ist mit 10.000 Euro dotiert. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

New Healthcare Services for Chronic Disease Sufferers

Interested in founding your own company to offer new prevention and treatment options for those suffering from or at-risk of chronic disease? The European Summer School for Innovation in Chronic Disease Intervention (euVENTION) from 11 to 22 September 2017 at Heidelberg University will focus on that challenging endeavour. Start-up Management of Heidelberg University along with Heidelberg Startup Partners and a number of other institutions is organising the summer school, which is open to doctoral candidates as well as students and recent graduates of all disciplines. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Neue Gesundheitsdienstleistungen für Menschen mit chronischer Erkrankung

Mit einem eigenen Unternehmen neue Präventions- und Behandlungsmöglichkeiten für Menschen mit chronischen Krankheiten oder dem Risiko einer Erkrankung anbieten? Dieser Herausforderung widmet sich die „European Summer School for Innovation in Chronic Disease Intervention“ (euVENTION), die vom 11. bis 22. September 2017 an der Universität Heidelberg stattfindet. Die Sommerschule, die sich an Doktoranden, aber auch an Studierende und junge Berufseinsteiger aller Fachgebiete wendet, wird vom Gründungsmanagement der Ruperto Carola und dem Verein Heidelberg Startup Partners gemeinsam mit verschiedenen Partnern veranstaltet. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Expanding the reach of therapeutic antibodies

A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy. (Mehr in: Cancer News — ScienceDaily)

The power of radiomics to improve precision medicine

Precision medicine has become the leading innovation of cancer treatment. Patients are routinely treated with drugs that are designed to target specific tumors and molecules. Despite the progress that has been made in targeted cancer therapies, the path has been slow and scientists have a long road ahead. In a collaborative project, investigated the emerging field of radiomics has the potential to improve precision medicine by non-invasively assessing the molecular and clinical characteristics of lung tumors. (Mehr in: Cancer News — ScienceDaily)

Maviret® erhält Zulassung zur pangenotypischen 8-Wochen-Therapie der chronischen Hepatitis C

Mit Maviret (Glecaprevir/Pibrentasvir; G/P) steht ab sofort für den Großteil aller Hepatitis-C-Patienten, unabhängig vom Genotyp, eine einmal tägliche 8-Wochen-Therapie zur Verfügung. (1,2)

Das beschleunigte Zulassungsverfahren unterstreicht die Innovationskraft dieser Wirkstoffkombination.

In den Zulassungsstudien erreichten bis zu 100 % der untersuchten therapienaiven* Patienten ohne Zirrhose der Genotypen 1–6 nach 8-wöchiger Behandlung mit Maviret eine SVR12 (sustained virologic response 12 Wochen nach Therapieende). (2,3) (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Cancer news

New findings explain how UV rays trigger skin cancer

18. Okt. 2017

Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the US in 2017, according to the Centers for Disease Control and Prevention. A fraction of those melanomas come from pre-existing moles, but the majority of them come from sources unknown — until now. (Mehr in: Cancer News — ScienceDaily)

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Researchers release the brakes on the immune system

18. Okt. 2017

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural “brakes” in the immune defense mechanism, which normally prevent an excessive immune response. Researchers have now been able to take off one of these brakes. The study could pave the way for more effective cancer therapies, they say. (Mehr in: Cancer News — ScienceDaily)

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Yeast spotlights genetic variation’s link to drug resistance

18. Okt. 2017

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists show that high genetic diversity can prime new mutations that cause drug resistance. The study has implications for our understanding of the evolution of resistance to antimicrobial and anticancer drugs. (Mehr in: Cancer News — ScienceDaily)

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Battling flames increases firefighters‘ exposure to carcinogens

18. Okt. 2017

The threat of getting burned by roaring flames is an obvious danger of firefighting, but other health risks are more subtle. For example, firefighters have been found to develop cancer at higher rates than the general population. Now researchers have measured how much firefighters‘ exposure to carcinogens and other harmful compounds increases when fighting fires. Their study also points to one possible way to reduce that exposure. (Mehr in: Cancer News — ScienceDaily)

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Machine learning identifies breast lesions likely to become cancer

18. Okt. 2017

A machine learning tool can help identify which high-risk breast lesions are likely to become cancerous, according to a new study. Researchers said the technology has the potential to reduce unnecessary surgeries. (Mehr in: Cancer News — ScienceDaily)

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Therapeutic form of arsenic is a potential treatment for deadly type of brain cancer

17. Okt. 2017

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element may be a potent force against cancer. (Mehr in: Cancer News — ScienceDaily)

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Cancer: New compound targets energy generation, thereby killing metastatic cells

17. Okt. 2017

Researchers have identified an enzyme that supports the survival and dissemination of metastatic cells, and developed a synthetic compound that targets the enzyme and kills the metastatic cells in mice with cancer. (Mehr in: Cancer News — ScienceDaily)

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Timing of melanoma diagnosis, treatment critical to survival

17. Okt. 2017

A new study underscores the importance of early detection and treatment of melanoma, the deadliest form of skin cancer. The research indicates that the sooner patients were treated, the better their survival, particularly for stage I melanoma. (Mehr in: Cancer News — ScienceDaily)

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Many pelvic tumors in women may have common origin: Fallopian tubes

17. Okt. 2017

Most, and possibly all, ovarian cancers start, not in ovaries, but instead in the fallopian tubes attached to them, report investigators. (Mehr in: Cancer News — ScienceDaily)

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Novel mechanism of resistance to anti-cancer drugs

17. Okt. 2017

Investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings suggest a strategy for overcoming this resistance. (Mehr in: Cancer News — ScienceDaily)

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Biology of childhood brain tumor subtypes offers clues to precision treatments

17. Okt. 2017

Researchers investigating pediatric low-grade gliomas (PLGG), the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer. By shedding light on subtle distinctions in tumor biology, these findings offer clues to designing more effective anticancer treatments to precisely target tumors in individual patients. (Mehr in: Cancer News — ScienceDaily)

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Bolstering fat cells offers potential new leukemia treatment

16. Okt. 2017

Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, says a new study. Researchers found that boosting adipocytes, or fat cells, located in the bone morrow suppressed cancerous leukemia cells but — in a surprise to the research team — also induced the regeneration of healthy blood cells. (Mehr in: Cancer News — ScienceDaily)

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Scientists identify biomarker for progression, drug response in brain cancer

16. Okt. 2017

Scientists have reported results from a glioblastoma study in which they validated a biomarker indicative of a patient’s prognosis and likely response to specific therapies. (Mehr in: Cancer News — ScienceDaily)

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Scientists demonstrate path to linking the genome to healthy tissues, disease

16. Okt. 2017

A study has reached a major milestone in establishing a baseline understanding of gene expression across healthy human tissues, and linking genes to disease. (Mehr in: Cancer News — ScienceDaily)

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Scientists reveal the relationship between sugar, cancer

13. Okt. 2017

A nine-year joint research project has led to a crucial breakthrough in cancer research. Scientists have clarified how the Warburg effect, a phenomenon in which cancer cells rapidly break down sugars, stimulates tumor growth. This discovery provides evidence for a positive correlation between sugar and cancer, which may have far-reaching impacts on tailor-made diets for cancer patients. (Mehr in: Cancer News — ScienceDaily)

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Liquid biopsy for retinoblastoma

12. Okt. 2017

A new study provides proof of concept for a safe and effective way to derive genetic information from a retinoblastoma tumor. (Mehr in: Cancer News — ScienceDaily)

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3D packaging of DNA regulates cell identity

12. Okt. 2017

The ability of a stem cell to differentiate into cardiac muscle (and by extension other cell types) depends on what portions of the genome are available for activation, which is controlled by the location of DNA in a cell’s nucleus, new research suggests. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

1st Gießen Symposium of Insect Biotechnology

01. Okt. 2017

We are delighted to invite delegates to the 1st Gießen Symposium for Insect Biotechnology. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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19th Herbstakademie

01. Okt. 2017

Embodied Aesthetics: Resonance in Perception, Expression and Therapy (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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17. Wissenschaftliche Jahrestagung der DGSF

01. Okt. 2017

Von der Neutralität zur Parteilichkeit – SystemikerInnen mischen sich ein (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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16. Deutscher Kongress für Versorgungsforschung

01. Okt. 2017

Unter dem Thema: „Zukunft Regionale Versorgung – Forschung, Innovation, Kooperation“ wird vom 4. bis 6. Oktober 2017 der 16. Deutsche Kongress für Versorgungsforschung (DKVF2016) in der Urania in Berlin stattfinden. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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100 Jahre Zukunft. Die Mistel in der Krebstherapie

01. Okt. 2017

Die Misteltherapie – immer noch umstritten oder längst etabliert? Antworten auf diese Frage gibt es beim Symposium „100 Jahre Zukunft. Die Mistel in der Krebstherapie“ am 21. Oktober 2017 in Berlin. Das Symposium richtet sich an Ärzte, Pharmazeuten, Therapeuten, Pflegende und Patienten. Theorie und Praxis kommen gleichermaßen zu Wort: Best-Practice, Erfahrungen und spannende Forschungsergebnisse werden vorgestellt. Diskussionen und Roundtables ergänzen das Programm. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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100 Jahre Max-Planck-Institut für Physik – Jubiläumssymposium und Festakt

01. Okt. 2017

Das Max-Planck-Institut für Physik begeht seinen 100. Jahrestag: Am 1. Oktober 1917 nahm das damalige Kaiser-Wilhelm-Institut für Physik unter Direktor Albert Einstein seine Arbeit auf. Dieses Jubiläum feiert das MPI für Physik mit einem wissenschaftlichen Symposium, das vom 10. bis 12. Oktober 2017 stattfindet. Ein anschließender Festakt mit Abendprogramm beschließt die Feierlichkeiten zum 100-jährigen Bestehen des Instituts. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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22. International Biohydrometallurgy Symposium

01. Sep. 2017

Call for Papers is open – submit your contribution until 10 January 2017

The biannual International Biohydrometallurgy Symposium is the global forum for experts from academia and industry active in the fields of biomining, bioleaching and bioremediation. These technologies have a high potential to establish environmentally favourable processes for the recovery of primary and secondary precious and base metal resources as well as the remediation of exploited mining sites. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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