Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

[ read more ]

Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

[ read more ]

Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

[ read more ]

Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

[ read more ]

A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

[ read more ]

About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

[ read more ]

Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

[ read more ]

A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

[ read more ]

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

[ read more ]

Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

[ read more ]

Dear Readers – Hiatus From Blog

For five years, I have written summaries of current scientific literature in subjects related to how mind exists in nature. This has included research into human and animal brains, plants, microbes, and general cellular intelligence. In addition to the weekly blog posts, I have posted relevant articles and archived blog…

(Mehr in: Jon Lieff, M.D.)

Pathway to ‚rejuvenating‘ immune cells to fight cancers and infections

A new discovery of the mechanism of T cell exhaustion will lead to treatments to enhance immunotherapies against cancers and such viruses as HIV. (Mehr in: Cancer News — ScienceDaily)

How reliable are shells as climate archives?

Calcite shells of marine organisms such as scallops or clams provide an important archive for the climate reconstructions in previous ages. Climate studies increasingly also use the shell material thrown away near settlements by humans in prehistoric times. Geologist Peter Müller from the Leibniz Centre for Tropical Marine Research (ZMT) has now discovered a considerable potential for error when shells that have been heated for human consumption are used in paleoclimatic studies. His study has just been published in the journal “Scientific Reports”. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Wie zuverlässig sind Muscheln als Klimaarchive?

Für die Rekonstruktion des Klimas vergangener Zeiten stellen Kalkschalen von Meerestieren wie Muscheln ein wertvolles Archiv dar. Dabei nutzen Klimastudien zunehmend auch jenes Schalenmaterial, das Menschen in prähistorischer Zeit in der Nähe ihrer Siedlungen angehäuft haben. Der Geologe Peter Müller vom Leibniz-Zentrum für Marine Tropenforschung (ZMT) fand jedoch ein erhebliches Fehlerpotential bei paläoklimatischen Untersuchungen an Muscheln, die für den Verzehr erhitzt wurden. Die Studie ist kürzlich im Fachjournal „Scientific Reports“ erschienen. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Den Faktor Mensch im biologischen Flickflack der Küstengewässer erkennen

Biologische Langzeitdatenserien sind wertvolle Datenarchive, um Auswirkungen des menschlichen Einflusses auf die Ökosysteme oder Klima-getriebene Regime-Veränderungen zu identifizieren. In Küstengewässer jedoch, dort wo der Süßwasserzustrom von Land gemeinsam mit dem Wettergeschehen und lokalen Strömungen zu rasch wechselnden Werten von Salzgehalt, Temperatur und Sauerstoff führt, kommt ihre Aussagekraft an ihre Grenzen. Zu dominant sind die Reaktionen der Lebensgemeinschaften auf diese Umweltparameter. Einer Gruppe Warnemünder Wissenschaftler ist es nun gelungen mithilfe statistischer Verfahren weitere Einflussgrößen zu identifizieren. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

HIV status may affect the progression of HPV infection to cervical pre-cancer

Human papillomavirus (HPV) infection was more likely to develop into cervical pre-cancer in women living with human immunodeficiency virus, a study of Senegalese women has shown. (Mehr in: Cancer News — ScienceDaily)

HIV-Schutzverhalten so hoch wie noch nie – BZgA: Neue Motivstaffel der Kampagne LIEBESLEBEN

91 Prozent der über 16-Jährigen mit mehr als einem Sexualpartner oder einer Sexualpartnerin in den letzten 12 Monaten geben an, immer, häufig oder gelegentlich Kondome zu benutzen. Das ist der höchste Wert seit Beginn der Repräsentativbefragung „AIDS im öffentlichen Bewusstsein“, die die Bundeszentrale für gesundheitliche Aufklärung (BZgA) seit 1988 in regelmäßigen Abständen durchführt. Um das Schutzverhalten in der Bevölkerung auf einem hohen Niveau zu halten, motiviert die BZgA ab sofort mit einer neuen Motivstaffel von LIEBESLEBEN zur Nutzung von Kondomen in sexuellen Risikosituationen. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Hirnpräparate aus der NS-Zeit: Max-Planck-Gesellschaft will Nazi-Opfer identifizieren

In Archiven des Max-Planck-Instituts für Psychiatrie wurden Präparate von Euthanasie-Opfern aus der NS-Zeit entdeckt. Nun versuchen Forscher, die Identität der Opfer zu klären. (Mehr in: SPIEGEL ONLINE – Wissenschaft)

New approach makes cells resistant to HIV

Scientists have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus. Their experiments under lab conditions show that these resistant cells can quickly replace diseased cells, potentially curing the disease in a person with HIV. (Mehr in: Cancer News — ScienceDaily)

Neue Krebstherapie aus alten Medikamenten

Eine akademische Arbeitsgruppe am Kantonsspital St. Gallen fand ein altes, nicht mehr gebräuchliches HIV-Medikament, dessen Einsatz in der Therapie bestimmter Tumorerkrankungen Ansprechraten erzielt, die über denen der neuesten speziell entwickelten Krebsmedikamente liegt – bei deutlich geringeren Medikamentenkosten. Nun soll der molekulare Mechanismus dieser Wirkung ergründet werden. Finanziert wird das Forschungsprojekt durch Erträge aus einer Zustiftung der verstorbenen Geschwister Dr. Monika und Dr. Isabel Baumann an die Wilhelm Sander-Stiftung. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Cancer news

Gold nanostars and immunotherapy vaccinate mice against cancer

17. Aug. 2017

By combining an FDA-approved cancer immunotherapy with an emerging tumor-roasting nanotechnology, researchers improved the efficacy of both therapies in a proof-of-concept study using mice. The potent combination also attacked satellite tumors and distant cancerous cells, completely curing two mice and effectively vaccinating one against the disease. (Mehr in: Cancer News — ScienceDaily)

- Read more

New terahertz imaging approach could speed up skin cancer detection

17. Aug. 2017

Researchers have developed a new terahertz imaging approach that, for the first time, can acquire micron-scale resolution images while retaining computational approaches designed to speed up image acquisition. (Mehr in: Cancer News — ScienceDaily)

- Read more

New Pathology Atlas maps genes in cancer to accelerate progress in personalized medicine

17. Aug. 2017

A new Pathology Atlas is launched today with an analysis of all human genes in all major cancers showing the consequence of their corresponding protein levels for overall patient survival. The difference in expression patterns of individual cancers observed in the study strongly reinforces the need for personalized cancer treatment based on precision medicine. (Mehr in: Cancer News — ScienceDaily)

- Read more

Scientists develop novel immunotherapy technology for prostate cancer

17. Aug. 2017

A novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA to directly encode protective antibodies against a cancer-specific protein has been described in a new article. (Mehr in: Cancer News — ScienceDaily)

- Read more

Are stem cells the link between bacteria and cancer?

17. Aug. 2017

A new mechanism of stomach gland regeneration reveals impact of Helicobacter pylori infection. (Mehr in: Cancer News — ScienceDaily)

- Read more

Energy dense foods may increase cancer risk regardless of obesity status

17. Aug. 2017

While there is a proven link between obesity and certain types of cancer, less is known about how the ratio of energy to food weight, otherwise known as dietary energy density (DED), contributes to cancer risk. To find out, researchers looked at DED in the diets of post-menopausal women and discovered that consuming high DED foods was tied to a 10 percent increase in obesity-related cancer among normal weight women. (Mehr in: Cancer News — ScienceDaily)

- Read more

New strategy to treat aggressive lung cancer

16. Aug. 2017

Research on a novel therapeutic avenue for an aggressive and difficult to treat subgroup of lung cancer has now been shared in a new article. (Mehr in: Cancer News — ScienceDaily)

- Read more

Problems with DNA replication can cause epigenetic changes that may be inherited for several generations

16. Aug. 2017

Scientists reveal that a fault in the process that copies DNA during cell division can cause epigenetic changes that may be inherited for up-to five generations. They also identified the cause of these epigenetic changes, which is related to the loss of a molecular mechanism in charge of silencing genes. Their results will change the way we think about the impact of replication stress in cancer and during embryonic development, as well as its inter-generational inheritance. (Mehr in: Cancer News — ScienceDaily)

- Read more

Popular immunotherapy target turns out to have a surprising buddy

16. Aug. 2017

The majority of current cancer immunotherapies focus on PD-L1. This well-studied protein turns out to be controlled by a partner, CMTM6, a previously unexplored molecule that is now suddenly also a potential therapeutic target. (Mehr in: Cancer News — ScienceDaily)

- Read more

Toxic formaldehyde is produced inside our own cells, scientists discover

16. Aug. 2017

New research has revealed that some of the toxin formaldehyde in our bodies does not come from our environment — it is a by-product of an essential reaction inside our own cells. This could provide new targets for developing cancer therapies. (Mehr in: Cancer News — ScienceDaily)

- Read more

Multicolor MRIs could aid disease detection

16. Aug. 2017

Researchers have developed a method that could make magnetic resonance imaging — MRI — multicolor. Current MRI techniques rely on a single contrast agent injected into a patient’s veins to vivify images. The new method uses two at once, which could allow doctors to map multiple characteristics of a patient’s internal organs in a single MRI. The strategy could serve as a research tool and even aid disease diagnosis. (Mehr in: Cancer News — ScienceDaily)

- Read more

Estrogen receptor stem cells found in mammary glands

16. Aug. 2017

One of the key questions in stem cell and cancer biology is to understand the cellular hierarchy governing tissue development and maintenance and the cancer cell of origin. Researchers have now identified a novel lineage – restricted stem cell in the mammary gland. In the future, this model will be used to assess whether the clinical heterogeneity observed in breast cancers arises from their different cancer cell of origin. (Mehr in: Cancer News — ScienceDaily)

- Read more

Combination of traditional chemotherapy, new drug kills rare cancer cells in mice

16. Aug. 2017

An experimental drug combined with the traditional chemotherapy drug cisplatin, when used in mice, destroyed a rare form of salivary gland tumor and prevented a recurrence within 300 days, a study found. (Mehr in: Cancer News — ScienceDaily)

- Read more

How decision-making habits influence the breast cancer treatments women consider

15. Aug. 2017

A new study finds that more than half of women with early stage breast cancer considered an aggressive type of surgery to remove both breasts. The way women generally approach big decisions, combined with their values, impacts what breast cancer treatment they consider, the study also found. (Mehr in: Cancer News — ScienceDaily)

- Read more

Birth defects, cancer linked

15. Aug. 2017

Some children born with birth defects may be at increased risk for specific types of cancer, according to a new review. (Mehr in: Cancer News — ScienceDaily)

- Read more

Epigenetic drugs show promise as antivirals

15. Aug. 2017

Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a new study. The study demonstrated that histone methyltransferases EZH2/1 inhibitors, which are being used in cancer clinical trials, have activity against a variety of viruses, including herpes simplex virus (HSV). (Mehr in: Cancer News — ScienceDaily)

- Read more

Protein that inhibits the development of autoimmune diseases discovered

15. Aug. 2017

The immune system protects humans from threats such as, for example, disease-causing bacteria, and cancer as well. Yet if the system malfunctions, it can attack the body it is supposed to defend and cause autoimmune diseases such as type one diabetes mellitus or multiple sclerosis. Scientists have now demonstrated that the membrane protein Caveolin-1 plays a key role in immune responses that trigger this type of disease. (Mehr in: Cancer News — ScienceDaily)

- Read more

Veranstaltungen

25. Wiss. Symposium für Psychotherapie: Veränderbarkeit – Ändern/Verändern/Anders am 13./14.10.2017

12. Aug. 2017

1992 wurde das Wissenschaftliche Symposium für Psychotherapie eingeführt. 25 Jahre später lädt die LWL-Universitätsklinik Bochum für Psychosomatische Medizin und Psychotherapie zu einem Jubiläumssymposium ein. Was hat sich verändert und welche Entwicklungen sind zu erwarten? Psychotherapie will ändern und stellt sich der Frage nach der Veränderbarkeit eines Menschen. Die Vorträge reichen von (epi)genetischen über soziologische, kulturelle bis hin zu psychotherapeutischen Themen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

Bavarian Summer School 2017 – The Future of Health Care

24. Jul. 2017

From 24/07/ until 04/08/17 the first summer school organized by Study & Work International, an initiative of the Bavarian Association of Universities of Applied Sciences (UAS), takes place at the Lutheran UAS Nuremberg and the technical UAS OTH Amberg-Weiden.The Future of Health Care: New Concepts – New Technologies is the topic of this two-week interdisciplinary summer school for Bachelor’s students from the fields of health care as well as various engineering disciplines (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

15th EUROPEAN CONFERENCE ON ORGANIZED FILMS

08. Jul. 2017

The 15th European Conference on Organized Films (ECOF 15) adds to a successful series of conferences addressing latest findings and advances in the field of thin and ultrathin organic films as well as nanoscience and -technologies. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

14th Dortmund MST Conference – Individualized Healthcare Solutions

05. Jul. 2017

Embracing „Individualized Healthcare Solutions“, the 14th Dortmund MST Conference on July 5, 2017 will present microsystems, production processes and digital technologies for use in medical technology and healthcare. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

14. Dortmunder MST-Konferenz – Individualisierte Gesundheitslösungen

05. Jul. 2017

Unter dem Motto „Individualisierte Gesundheitslösungen“ präsentiert die 14. Dortmunder MST-Konferenz am 5. Juli 2017 Mikrosysteme, mikrotechnische Fertigungsverfahren und digitale Technologien für den Einsatz in der Medizintechnik und Gesundheitsversorgung. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

14. HepNet Symposium

02. Jun. 2017

Akkreditiert: mit 10 CME-Punkten von der Ärztekammer Niedersachsen mit 13 iCME-Punkten von der Akademie für Infektionsmedizin

Wissenschaftliche Leitung: Prof. Dr. med. Michael P. Manns, Hannover Prof. Dr. med. Stefan Zeuzem, Frankfurt Prof. Dr. med. Claus Niederau, Oberhausen Prof. Dr. med. Ulrike Protzer, München Prof. Dr. med. Peter Schirmacher, Heidelberg (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

Art / Nature:Contemporary Art in Natural History Museums and Collections

02. Jun. 2017

A pilot project in cooperation with the German Federal Cultural Foundation.

The conference outlines recent and ongoing art projects and art programmes in natural history museums and in the natural history collections of multidisciplinary museums. In doing so, it aims to reflect upon and discuss the expectations, potentials, possible limitations and values of these kinds of interactions and interventions from the perspectives of curators, artists and researchers. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen