Schlagwort: fungus
A single molecule upsets symbiosis
5. Juli 2023
A new study on the coexistence of bacteria and fungi shows that a mutually beneficial, functioning symbiosis can be very fragile. Researchers at the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) in Jena found out that the bacterial species Mycetohabitans rhizoxinica lives happily in the hyphae of the fungus Rhizopus microsporus only when the bacteria produce a certain protein.
Resistant fungal species spreads
13. Mai 2023
The number of infections with the fungus Candida auris is also increasing in Germany. This is shown in a new study by research teams from Würzburg, Jena and Berlin. Despite low numbers, scientists advise precautionary measures.
Fungal spores hijack lung cells
9. März 2023
The pathogenic fungus Aspergillus fumigatus escapes elimination from surface cells of the human lung by binding to a human protein. In doing so, it is able to nest in so called phagosomes, confined areas in the lung cells, and thus prevents cell processes that would kill the fungus from being set in motion. Researchers at the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) have thus discovered a possible new target against the fungal infection.
Microbes protect a leaf beetle – but for a price
20. August 2022
Insects are known to rely on microbial protection during immobile developmental stages, such as eggs. But despite the susceptibility of pupae to antagonistic challenges, the role of microbes in ensuring defense during an insect’s metamorphosis remained an open question. Scientists from Germany and Panama have now discovered a novel defensive partnership between a fungus and a leaf beetle. The microbe provides a protective layer around the beetle´s pupae and thus prevents predation. In exchange, the beetle disperses the fungus to its host plant, expanding its range. Now published in Current Biology, the researchers present the results of their study.
How a harmful fungus renders its host plant defenseless
10. August 2022
The fungus Ustilago maydis attacks corn and can cause significant damage to its host. To do this, it first ensures that the plant offers little resistance to the infection. The surgical precision it applies is shown by a new study from the University of Bonn, which has now been published in the journal New Phytologist. The Gregor Mendel Institute in Vienna and the Leibniz Institute of Plant Genetics and Crop Plant Research in Gatersleben were also involved in the work.
Fragile balance in the gut – Intestinal cells and lactic acid bacteria work together against Candida infection
21. Juni 2022
The presence of probiotics such as lactic acid bacteria changes the environment in the intestine and forces the yeast fungus Candida albicans to change its metabolism, making it less infectious. This way, probiotics can contain or prevent the spread of fungal infections in the gut. Researchers at the Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (Leibniz-HKI) have also found that intestinal cells actively promote bacterial growth to protect themselves from the fungus. The findings were published in Nature Communications.
How a fungus hijacks our immune system
8. Februar 2022
During infection, the yeast Candida albicans stimulates the release of tiny RNA fragments, which then stimulate its own growth. An international research team led by the Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (Leibniz-HKI) in Jena has discovered this unusual exploitation of the human immune system. The findings can explain disease processes and provide new approaches for the therapy of fungal infections. The results were published in the journal mBio.
A plant–fungus partnership is at the origin of terrestrial vegetation
21. Mai 2021
Plants that exist on land today have genes that allow them to exchange valuable lipids with beneficial fungi. This plant–fungus partnership is at the origin of the transition of plants from aquatic life to terrestrial life.
How European hibernating bats cope with white-nose syndrome which kills millions of North American bats
3. Februar 2021
Fungal diseases are a major threat to wildlife, sometimes resulting in significant population declines or even causing the extirpation of populations or species. White-nose syndrome, caused by the cold-loving fungus Pseudogymnoascus destructans, has become a major cause of death for hibernating bats in North America. European bats survive when infected by the same fungus during hibernation. What are the reasons for such a contrast in outcomes? A scientist team led by the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) has now analysed the humoral innate immune defence of European greater mouse-eared bats to the fungus.