Ebola, Nipah, and ???: ’Plug-and-Play’ for the rapid production of protective antibodies

Epidemics caused by dangerous pathogens such as Ebola virus can occur without warning. The administration of protective antibodies against a pathogen is one approach to save lives and reduce the number of victims. How can they be produced quickly and in large quantities in the event of outbreaks? Researchers at the Paul-EhrlichInstitut with scientists at DZIF (German Center for Infection Research) have shown that adjuvanted virus-like particles (VLPs) could be used as a plug-and-play system to rapidly generate functional antibodies in animals that could then be used to treat infected individuals. The results are reported in the online edition of npj Vaccines on 05.10.2018. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)