Unusual virus defence decoded in the brain – new approach for virus encephalitis therapy

Our brain is one of the most protected organs of the body. The blood-brain barrier allows only selected substances to pass into the central nervous system. Nevertheless, the brain also has vulnerabilities: Viruses can exploit the odorant system to enter the brain. Upon entry of viruses into the brain via this route, the brain becomes inflamed and life-threatening encephalitis can develop as a consequence. Scientists at TWINCORE have uncovered a specific immune response in the brain which is based on completely different mechanisms than the defense against pathogens in the rest of the body. Recently, they published their discovery in the Journal Cell Reports. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)