Master of the tree – novel form of dendritic inhibition discovered

A unique feature that sets neurons apart from all other cells are their beautiful, highly elaborate dendritic trees. These structures have evolved to receive the vast majority of information entering a neuron, which is integrated and processed by virtue of the dendrites’ geometry and active properties. Higher brain functions such as memory and attention all critically rely on dendritic computations, which are in turn controlled by inhibitory synaptic input. A team of scientists, led by Johannes J. Letzkus (MPI for Brain Research), now has identified a novel form of inhibition that dominantly controls dendritic function and strongly depends on previous experiences. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)