Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Kidnapping in the Antarctic animal world?

A puzzling relationship between amphipods and pteropods (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

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Cancer news

New inflammation inhibitor discovered

15. Nov. 2018

A multidisciplinary team of researchers have developed an anti-inflammatory drug molecule with a new mechanism of action. By inhibiting a certain protein, the researchers were able to reduce the signals that trigger an inflammation. (Mehr in: Cancer News — ScienceDaily)

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Drug combination makes cancer disappear in mice with neuroblastoma

15. Nov. 2018

Researchers investigating new treatments for neuroblastoma — one of the most common childhood cancers — have found that a combination of two drugs made tumors disappear in mice, making it more effective than any other drugs tested in these animals. (Mehr in: Cancer News — ScienceDaily)

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A new approach to detecting cancer earlier from blood tests

14. Nov. 2018

Cancer scientists have combined ‚liquid biopsy,‘ epigenetic alterations and machine learning to develop a blood test to detect and classify cancer at its earliest stages. (Mehr in: Cancer News — ScienceDaily)

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Rainforest vine compound starves pancreatic cancer cells

14. Nov. 2018

Pancreatic cancer cells are known for their ability to thrive under extreme conditions of low nutrients and oxygen, a trait known in the cancer field as ‚austerity.‘ The cells‘ remarkable resistance to starvation is one reason why pancreatic cancer is so deadly. Now researchers have identified a compound from a Congolese plant that has strong “antiausterity“ potential, making pancreatic cancer cells susceptible to nutrient starvation. (Mehr in: Cancer News — ScienceDaily)

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Synthetic DNA-delivered antibodies protect against Ebola in preclinical studies

13. Nov. 2018

Scientists have successfully engineered novel DNA-encoded monoclonal antibodies (DMAbs) targeting Zaire Ebolavirus that were effective in preclinical models. Study results showed that DMAbs were expressed over a wide window of time and offered complete and long-term protection against lethal virus challenges. DMAbs may also provide a novel powerful platform for rapid screening of monoclonal antibodies enhancing preclinical development. (Mehr in: Cancer News — ScienceDaily)

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New methods to identify Alzheimer’s drug candidates with anti-aging properties

13. Nov. 2018

Old age is the greatest risk factor for many diseases, including Alzheimer’s disease (AD) and cancer. Geroprotectors are a recently identified class of anti-aging compounds. New research has now identified a unique subclass of these compounds, dubbed geroneuroprotectors (GNPs), which are AD drug candidates and slow the aging process in mice. (Mehr in: Cancer News — ScienceDaily)

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‚Waltzing‘ nanoparticles could advance search for better drug delivery methods

13. Nov. 2018

Scientists paired drug-delivering nanoparticles like dance partners to reveal that molecules attach to targets on cells differently based upon their position in time. The discovery could improve methods for screening drugs for therapeutic effectiveness. (Mehr in: Cancer News — ScienceDaily)

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Stealth-cap technology for light-emitting nanoparticles

13. Nov. 2018

Scientists have succeeded in significantly increasing the stability and biocompatibility of special light-transducing nanoparticles. They have developed so-called “upconverting“ nanoparticles that not only convert infrared light into UV-visible light, but also are water-soluble, remain stable in complex body fluids, and can be used to store medications. They have created a tool that could potentially make the fight against cancer more effective. (Mehr in: Cancer News — ScienceDaily)

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Cancer stem cells get energy from protein, and it’s proving to be their Achilles‘ heel

12. Nov. 2018

A new study shows that cancer stem cells switch from metabolizing sugar to metabolizing protein. Clinical trial based on this observation may revolutionize care for older adults with acute myeloid leukemia. (Mehr in: Cancer News — ScienceDaily)

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Weight during adolescence may affect pancreatic cancer risk in adulthood

12. Nov. 2018

New research has linked adolescent obesity with up to a four-fold increased risk of pancreatic cancer later in life. The study’s results also suggest that overweight and even higher weight within the ‚normal‘ weight range in men may increase pancreatic cancer risk in a graded manner. (Mehr in: Cancer News — ScienceDaily)

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Defective DNA damage repair leads to chaos in the genome

12. Nov. 2018

Scientists have now found a cause for the frequent catastrophic events in the genetic material of cancer cells that have only been known for a few years: If an important DNA repair system of the cells has failed, this promotes fragmentation and defective assembly of the genetic material. Cancer cells with such a repair defect can now possibly be treated by a specific group of drugs. (Mehr in: Cancer News — ScienceDaily)

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Decrease in specific gene ‚silencing‘ molecules linked with pediatric brain tumors

12. Nov. 2018

Experimenting with lab-grown brain cancer cells, researchers have added to evidence that a shortage of specific tiny molecules that silence certain genes is linked to the development and growth of pediatric brain tumors known as low-grade gliomas. (Mehr in: Cancer News — ScienceDaily)

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Hidden estrogen receptors in breast epithelium

09. Nov. 2018

Scientists have uncovered that next to estrogen receptor positive and negative there are cells with very low amounts of the receptor protein. The discovery has significant implications for the role of the receptor in the growth and development of the breast and breast cancer development. (Mehr in: Cancer News — ScienceDaily)

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Scientists solve century-old neuroscience mystery; answers may lead to epilepsy treatment

09. Nov. 2018

Scientists have solved a 125-year-old mystery of the brain, and, in the process, uncovered a potential treatment for acquired epilepsy. Perineuronal nets modulate electrical impulses in the brain, and, should the nets dissolve, brain seizures can occur. (Mehr in: Cancer News — ScienceDaily)

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Genetic ‚whodunnit‘ for cancer gene solved

08. Nov. 2018

Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, researchers have solved the long-standing mystery around why AMPK can both hinder and help cancer. (Mehr in: Cancer News — ScienceDaily)

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What do metastatic cancer cells have in common with sharks?

08. Nov. 2018

In a new study, researchers report that when cancer cells become invasive (metastatic), they start behaving in ‚predatory‘ ways. Metastatic cancer cells differ from their non-metastatic counterparts not only in their genetics, but also in their moving strategy: they spread more rapidly and are more directional than non-invasive cancer cells. (Mehr in: Cancer News — ScienceDaily)

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Combination chemotherapy and immunotherapy effective in Phase II leukemia study

08. Nov. 2018

A combination of the standard-of-care chemotherapy drug known as azacitidine, with nivolumab, an immune checkpoint inhibitor, demonstrated an encouraging response rate and overall survival in patients with relapsed or refractory acute myeloid leukemia, according to new findings. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

21. Deutsche Mukoviszidose Tagung (DMT)

01. Nov. 2018

Jedes Jahr im November veranstaltet der Mukoviszidose e.V. die Deutsche Mukoviszidose Tagung. An drei Tagen (22.-24.11.2018) wird ein breites Fort- und Weiterbildungsangebot für das interdisziplinäre Mukoviszidose-Behandler-Team präsentiert. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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21. Deutsche Mukoviszidose Tagung

01. Nov. 2018

Die Deutsche Mukoviszidose Tagung – mit jährlich rund 800 Teilnehmerinnen und Teilnehmern die größte Fortbildungsveranstaltung zur Mukoviszidose in Deutschland – richtet sich an das gesamte Behandler-Team und verbindet interdisziplinäre Fragestellungen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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1. Community Health Konferenz in Bochum

01. Nov. 2018

Das Department of Community Health (DoCH) der Hochschule für Gesundheit (hsg Bochum) veranstaltet die erste Community Health Konferenz an der hsg Bochum. Die Konferenz ist als Auftakt für eine jährliche Veranstaltung geplant, welche Wissenschaft, Praxis und Lehre anspricht und zusammenführt. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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100 Jahre Influenza – Wie gut sind wir für die nächste Pandemie vorbereitet?

01. Nov. 2018

Weshalb traf die Spanische Grippe, ausgelöst von einem H1N1 Influenzavirus, die Welt derart unvorbereitet? Wie gut wären wir gegen eine kommende Pandemie aufgestellt? Diesen Fragen der modernen Medizin geht Prof. Dr. Gülsah Gabriel in ihrem Vortrag zu 100 Jahren Influenza nach. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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4. BfR-Symposium Lebensmittelassoziierte Viren

01. Nov. 2018

Das 4. BfR-Symposium „Lebensmittelassoziierte Viren“ soll einen Austausch über Aspekte wie die aktuelle epidemiologische Situation einzelner Virusinfektionen, neuartige Nachweismethoden für Viren in Lebensmitteln oder Möglichkeiten für eine verbesserte Hygiene ermöglichen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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3. Tag der Arbeitsmedizin in Köln

01. Nov. 2018

Dialogforen Arbeitsmedizin und Arbeitssicherheit – Eine Veranstaltungsreihe für Wissenschaft und Praxis der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V. (DGAUM) und RG GmbH (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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38. Marktplatz Gesundheit: „Klinische Bewertung nach der neuen MDR – die Zeit läuft“

01. Nov. 2018

Medizintechnik ist Technik für Menschen. Wer sie entwickelt, herstellt und vertreibt, unterliegt daher besonderen Vorschriften. Maßgeblich dafür ist die EU-Verordnung zu Medizinprodukten (Medical Device Regulation = MDR), welche durch die europäische Zulassung ab 2020 einheitlich geregelt wird. Dies bringt viele Änderungen mit sich. Jeder Hersteller von Medizinprodukten muss sich mit den neuen Anforderungen auseinandersetzen. Es gibt also viel zu bereden! (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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