Protein complex for hepatitis C-virusentry in liver cells is characterised

Hepatitis C virus chronically infects 70 million individuals worldwide. Although the infection can be cured with antiviral drugs, this therapy does not protect from a second infection with the same virus. Moreover, the liver damage cannot always be reversed by treatment of hepatitis C. The team “Viral Interaction Proteomics” led by Gisa Gerold at the Institute for Experimental Virology at TWINCORE used a new sensitive analytical method to identify proteins in the membrane of liver cells, which mediate entry of hepatitis C virus. These results were recently published in PLOS Pathogens. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)