“Flashing blue light” in the cell – the m6A modification regulates speed of RNA processing

A controlled interaction of genes in the organism requires that every gene must be in the right place at the right time. In addition, the speed is important, in which the RNA is further processed after transcription. Now, scientists from the Max Planck Institute for Molecular Genetics and the University of Aarhus have described an RNA modification that influences the rate of mRNA processing by its position. They found that precursor mRNAs having the modification N-6-methyladenosine (m6A) deposited at the junction between coding- and non-coding regions are processed much faster than those without the m6A modification. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)