A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

[ read more ]

Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

[ read more ]

A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

[ read more ]

About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

[ read more ]

Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

[ read more ]

Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

[ read more ]

Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

[ read more ]

Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

[ read more ]

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

[ read more ]

Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

[ read more ]

Mechanism vital to keeping blood stem cells functional uncovered

Hematopoietic stem cells, that form mature blood cells, require a very precise amount of protein to function — and defective regulation of protein production is common in certain types of aggressive human blood cancers. Now, a research team has uncovered a completely new mechanism that controls how proteins are produced to direct stem cell function. (Mehr in: Cancer News — ScienceDaily)

Comments are closed.

Cancer news

Looking at the urine and blood may be best in diagnosing myeloma

13. Jul. 2018

When it comes to diagnosing a condition in which the plasma cells that normally make antibodies to protect us instead become cancerous, it may be better to look at the urine as well as the serum of our blood for answers, pathologists say. (Mehr in: Cancer News — ScienceDaily)

- Read more

Massive genome havoc in breast cancer is revealed

12. Jul. 2018

Researchers using long-read DNA sequencing have made one of the most detailed maps ever of structural variations in a cancer cell’s genome. The map reveals about 20,000 structural variations, few of which have been noted before, in just one cell type associated with one form of breast cancer. (Mehr in: Cancer News — ScienceDaily)

- Read more

Gammaherpesviruses linked to tumors in macaques with simian immunodeficiency virus

12. Jul. 2018

Viruses known as gammaherpesviruses may raise the risk of cancer in macaques infected with Simian Immunodeficiency Virus or Simian Human Immunodeficiency Virus (SIV/SHIV), according to new research. (Mehr in: Cancer News — ScienceDaily)

- Read more

Solved protein puzzle opens door to new design for cancer drugs

12. Jul. 2018

Researchers at have solved a longstanding puzzle concerning the design of molecular motors, paving the way toward new cancer therapies. (Mehr in: Cancer News — ScienceDaily)

- Read more

Structure and key features of critical immune-surveillance protein in humans

12. Jul. 2018

Scientists have defined the structure and key features of a human immune-surveillance protein that guards against cancer and bacterial and viral infections. The identification of two human-specific variations in the protein closes a critical knowledge gap in immunology and cancer biology. (Mehr in: Cancer News — ScienceDaily)

- Read more

New method reveals how well cancer drugs hit their targets

12. Jul. 2018

Scientists have developed a method to measure how well cancer drugs reach their targets inside the body. It shows individual cancer cells in a tumor in real time, revealing which cells interact with the drug and which cells the drug fails to reach. The findings could help clinicians decide the best course and delivery of treatment for cancer patients in the future. (Mehr in: Cancer News — ScienceDaily)

- Read more

Optimizing pulsed electric fields to target cancer with calcium ions

12. Jul. 2018

When applied to cells, pulsed electric fields increase membrane permeability. Researchers have used this effect to force the diffusion of extracellular calcium into cells. Cell death occurs more easily in cancer cells since they are particularly sensitive to high amounts of calcium. Researchers have optimized pulsed electric field settings in an effort to attack cancer but leave healthy cells intact. (Mehr in: Cancer News — ScienceDaily)

- Read more

Scientists create nano-size packets of genetic code aimed at brain cancer ‚seed‘ cells

12. Jul. 2018

In a ‚proof of concept‘ study, scientists say they have successfully delivered nano-size packets of genetic code called microRNAs to treat human brain tumors implanted in mice. The contents of the super-small containers were designed to target cancer stem cells, a kind of cellular ‚seed‘ that produces countless progeny and is a relentless barrier to ridding the brain of malignant cells. (Mehr in: Cancer News — ScienceDaily)

- Read more

New perspective on tumor genome evolution

12. Jul. 2018

An interdisciplinary team of scientists deepens understanding of tumor genome evolution and suggests negative selection acting on cancer-essential genes plays a more important role than previously anticipated. The scientists‘ work also provides new insights for improving cancer immunotherapies in the future. (Mehr in: Cancer News — ScienceDaily)

- Read more

New control of cell division discovered

12. Jul. 2018

When a cell divides, its constituents are usually evenly distributed among the daughter cells. Researchers have now identified an enzyme that guarantees that cell constituents that are concentrated in organelles without a membrane are properly distributed. Their discovery opens up new opportunities for the treatment of cancer, neurodegenerative diseases, aging processes and viral infections. (Mehr in: Cancer News — ScienceDaily)

- Read more

Smell receptors in the body could help sniff out disease

12. Jul. 2018

A review of more than 200 studies reveals that olfactory receptors — proteins that bind to odors that aid the sense of smell — perform a wide range of mostly unknown functions outside the nose. The function of extra-nasal olfactory receptors has the potential to be used in the diagnosis and treatment of health conditions such as cancer. (Mehr in: Cancer News — ScienceDaily)

- Read more

Researchers clarify role of mutations in glioblastoma

11. Jul. 2018

Researchers investigated whether the location of the mutation within the sequence of the PIK3CA gene affected the mutation’s ability to help drive growth of glioblastoma tumors. They also evaluated whether the location of the mutation would affect the cancer’s response to certain treatments. (Mehr in: Cancer News — ScienceDaily)

- Read more

Engineered cancer cells can fight primary and metastatic cancer

11. Jul. 2018

A new study leverages the power of gene editing, capitalizing on cancer cells‘ self-homing ability to take a critical step toward using cancer cells to kill cancer. (Mehr in: Cancer News — ScienceDaily)

- Read more

Robotic surgery as effective as open surgery for bladder cancer

11. Jul. 2018

Robotic surgery is as effective as traditional open surgery in treating bladder cancer, according to a new study. (Mehr in: Cancer News — ScienceDaily)

- Read more

Why randomized trials for proton therapy are difficult to complete (and what we can do about it)

11. Jul. 2018

Commercial insurance medical policies that do not cover treatment with proton therapy can make it difficult for patients to participate in randomized clinical trials. (Mehr in: Cancer News — ScienceDaily)

- Read more

Rise of the clones

11. Jul. 2018

Researchers discover new clues about a recently identified blood cell condition known as clonal hematopoiesis, implicated in hematologic cancers, cardiovascular illness. Surprisingly, the study reveals that inherited genetic variants can drive the condition by fueling additional mutations later in life. The findings can help inform ways to gauge disease risk based on specific mutations, develop strategies to avert disease. Clonal hematopoiesis is estimated to affect more than 1 in 10 people older than 65. (Mehr in: Cancer News — ScienceDaily)

- Read more

T cell engineering breakthrough sidesteps need for viruses in gene-editing

11. Jul. 2018

In an achievement that has significant implications for research, medicine, and industry, scientists have genetically reprogrammed the human immune cells known as T cells without using viruses to insert DNA. The researchers said they expect their technique — a rapid, versatile, and economical approach employing CRISPR gene-editing technology — to be widely adopted in the burgeoning field of cell therapy, accelerating the development of new and safer treatments for cancer, autoimmunity, and other diseases, including rare inherited disorders. (Mehr in: Cancer News — ScienceDaily)

- Read more

Veranstaltungen

Sommerkolleg: Chemie, Physik und Materialwissenschaften

01. Jul. 2018

Das Sommerkolleg bietet Interessierten ab 16 Jahren die Möglichkeit einen vertieften Einblick in das Studium der Chemie und Physik sowie der Materialwissenschaften mit Vorlesungen und Praktika zu gewinnen. Es werden Praktika in der Anorganischen Chemie, der Organischen Chemie, in der Physik, Werkstofftechnik und Umformtechnik angeboten, sowie ein Einführungskurs in die Themenfelder Glas-Bindemittel und Kunststoffverarbeitung. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

RVZ Kolloquium: Prof. Michael Rape

01. Jul. 2018

Prof. Michael Rape from UC Berkeley (US) will talk about his research „The other code: roles of ubiquitin in neuronal development and neurodegeneration“ at the Rudolf Virchow Center of the University of Würzburg. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

Quantum Technology – Impact on Computing and Communication

01. Jul. 2018

Quantum technology forms the technological basis for the development of quantum computers, quantum sensors, quantum cryptography, and quantum communication systems. These technologies have the potential to disrupt a variety of existing industries. For example, quantum computers promise new possibilities for solving computing-intensive or previously not efficiently solvable problems. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

Personenzentrierung

01. Jul. 2018

Personenzentrierung: Bausteine für einen heilsamen Umgang bei Menschen mit Demenz zwischen Anspruch und Wirklichkeit. Auch im akademischen Jahr 2017/18 bietet die Philosophisch-Theologische Hochschule Vallendar (PTHV) wieder für die interessierte Öffentlichkeit eine Ringvorlesung an – dieses Mal zum Thema „Heil und Heilung“. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

Neue Entwicklungen des Rechts auf Gesundheit in Brasilien

01. Jul. 2018

Die brasilianische Bundesverfassung von 1988 enthält einen großzügigen Katalog sozialer Grundrechte, innerhalb dessen dem Recht auf Gesundheit eine besondere Bedeutung zukommt. Prof. Dr. Ingo Sarlet zeigt die jüngsten Entwicklungen hinsichtlich der Realisierung dieses Rechts auf. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

Heilung, Hoffnung, Loslassen. Sorge-Ethik am Lebensende.

01. Jul. 2018

Auch im akademischen Jahr 2017/18 bietet die Philosophisch-Theologische Hochschule Vallendar (PTHV) wieder für die interessierte Öffentlichkeit eine Ringvorlesung an – dieses Mal zum Thema „Heil und Heilung“. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen

Fachtagung Digitales Management von Patientendaten

01. Jul. 2018

Chancen und Kooperationsmöglichkeiten im Bereich E-Health

Die Tagung richtet sich an Vertreter von Herstellern und Dienstleistern aus dem Umfeld digitaler Lösungen für die Gesundheitsversorgung sowie an Leistungserbringer, Systemadministratoren, Kostenträger, behördliche und politische Entscheidungsträger und allen weiteren Akteuren, die in aktuelle E-Health Entwicklungen involviert sind. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

- Weiterlesen