A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Was macht die Kohlensäure im Mineralwasser mit unserem Körper?

Null Kalorien – und doch nicht ohne Nebenwirkungen

Mineralwasser mit Kohlensäure ist und bleibt ein Verkaufsschlager. Kann es auch Schaden anrichten?

(Mehr in: Medizin & Ernährung – FAZ.NET)

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Cancer news

Increasing incidence of rare skin cancer

16. Feb. 2018

While it may not be as common as other skin cancers, Merkel cell carcinoma is highly aggressive and often deadly — and according to new research, it’s also becoming more common. (Mehr in: Cancer News — ScienceDaily)

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Labs differ widely in BRCA testing protocols

15. Feb. 2018

A new article showcases the wide differences in BRCA testing protocols at labs around the world. The article surveyed 86 laboratories around the world about their BRCA testing practices and found that all the labs differed widely in their approach. (Mehr in: Cancer News — ScienceDaily)

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New mutation linked to ovarian cancer can be passed down through dad

15. Feb. 2018

A newly identified mutation, passed down through the X-chromosome, is linked to earlier onset of ovarian cancer in women and prostate cancer in father and sons. (Mehr in: Cancer News — ScienceDaily)

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CRISPR-based diagnostic tool advanced, miniature paper test developed

15. Feb. 2018

The team that first unveiled the rapid, inexpensive, highly sensitive CRISPR-based diagnostic tool called SHERLOCK has greatly enhanced the tool’s power to work with a miniature paper test, similar to a pregnancy test, allowing rapid and simple detection in any setting. Additional features greatly expand both the breadth and sensitivity of the diagnostic information, including the ability to detect multiple targets at once and quantify the amount of target in a sample. (Mehr in: Cancer News — ScienceDaily)

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How cancer cells repair themselves following proton beam therapy

15. Feb. 2018

New research identifies the specific cellular process that helps cancer cells damaged as a result of proton beam therapy, repair themselves. (Mehr in: Cancer News — ScienceDaily)

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Working in harmony: New insights into how packages of DNA orchestrate development

15. Feb. 2018

New research illuminates aspects of how an early embryo, the product of fertilization of a female egg cell by a male sperm cell, can give rise to all the many cell types of the adult animal. (Mehr in: Cancer News — ScienceDaily)

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Induced pluripotent stem cells could serve as cancer vaccine

15. Feb. 2018

Induced pluripotent stem cells, or iPS cells, are a keystone of regenerative medicine. Outside the body, they can be coaxed to become many different types of cells and tissues that can help repair damage due to trauma or disease. Now, a study in mice suggests another use for iPS cells: training the immune system to attack or even prevent tumors. (Mehr in: Cancer News — ScienceDaily)

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Can our genes help predict how women respond to ovarian cancer treatment?

15. Feb. 2018

New research has shown that the genes we inherit can have a significant impact on how the body processes chemotherapy drugs, which may lead to different clinical outcomes for ovarian cancer patients. (Mehr in: Cancer News — ScienceDaily)

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Accurate model of how aggressive cancer cells move and spread

15. Feb. 2018

Researchers have produced a new and freely available computer program that predicts cancer cell motion and spread with high accuracy. This new system gives researchers a faster way of examining rapidly spreading glioblastoma tumors — an aggressive and devastating form of brain cancer — and a new way of predicting the likely impact different treatments might have. (Mehr in: Cancer News — ScienceDaily)

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Cutting off cervical cancer’s fuel supply stymies tumors

14. Feb. 2018

Researchers have shown that cervical tumors that don’t respond to radiation may be vulnerable to therapies that also attack the cancer’s fuel supply. (Mehr in: Cancer News — ScienceDaily)

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Use of immunotherapy to treat aggressive colon tumors

14. Feb. 2018

Researchers have developed a mouse model that mimics advanced human colon cancer. This model has allowed them to study the immune system response for the first time. (Mehr in: Cancer News — ScienceDaily)

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Organ-on-chip technology enters next stage as experts test hepatitis B virus

14. Feb. 2018

Scientists are testing how pathogens interact with artificial human organs. (Mehr in: Cancer News — ScienceDaily)

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Cancer-killing virus acts by alerting immune system

13. Feb. 2018

A new study has shown that a cancer-killing (‚oncolytic‘) virus currently in clinical trials may function as a cancer vaccine — in addition to killing some cancer cells directly, the virus alerts the immune system to the presence of a tumor, triggering a powerful, widespread immune response that kills cancer cells far outside the virus-infected region. (Mehr in: Cancer News — ScienceDaily)

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Cabozantinib shows promise as first line treatment for differentiated thyroid cancer

13. Feb. 2018

A kinase inhibitor called cabozantinib could be a viable therapy option for patients with metastatic, radioactive iodine-resistant thyroid cancer. In a recent trial tumors shrunk in 34 out of 35 patients who took the drug, and more than half of those patients saw the tumor size decrease by more than 30 percent. (Mehr in: Cancer News — ScienceDaily)

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Screening for ovarian cancer not recommended

13. Feb. 2018

The US Preventive Services Task Force (USPSTF) recommends against screening for ovarian cancer in women without symptoms and who are not known to be at high risk (such as those who have certain hereditary cancer syndromes that increase the risk for ovarian cancer). (Mehr in: Cancer News — ScienceDaily)

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Light-activated cancer drugs without toxic side effects: Fresh insight

13. Feb. 2018

Future cancer drugs that are activated by light and don’t cause the toxic side-effects of current chemotherapy treatments are closer to becoming a reality, thanks to new research. (Mehr in: Cancer News — ScienceDaily)

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Obesity associated with longer survival for men with metastatic melanoma

13. Feb. 2018

Obese patients with metastatic melanoma who are treated with targeted or immune therapies live significantly longer than those with a normal body mass index (BMI), investigators report. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

3. Bucerius-Medizinrechtstag "Schnittstellenprobleme des Medizinrechts"

13. Feb. 2018

Eröffnung des Instituts für Medizinrecht an der Bucerius Law School (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Arbeitstagung NeuroIntensivmedizin (ANIM) 2018

01. Feb. 2018

Die ANIM 2018 ist die 35. Jahrestagung der Deutschen Gesellschaft für NeuroIntensiv- und Notfallmedizin und der Deutschen Schlaganfall-Gesellschaft und findet vom 8.–10. Februar 2018 in Würzburg statt. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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ADDITIVE FERTIGUNG – fokus: kunststoff

01. Feb. 2018

Schwerpunktthemen: • Innovationen für Material, Verfahren und Prozesse • Best-Practice-Lösungen für Consumer, Automotive und Medical • Konstruktion und Simulation neu gedacht • Betriebsfestigkeit, Sicherheit und Zuverlässigkeit • Qualifizierung, Zertifizierung und Zulassung (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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78. Jahrestagung der Deutschen Geophysikalischen Gesellschaft

01. Feb. 2018

Die Deutsche Geophysikalische Gesellschaft (DGG) veranstaltet jährlich eine große Fachtagung. Im Jahr 2018 erfolgt die Jahrestagung gemeinsam mit der Österreichischen Geophysikalischen Gesellschaft (Austrian Geophysical Society, AGS) in Leoben. Damit wollen die Gesellschaften in besonderem Maße ihr Interesse an internationalem Austausch und Zusammenarbeit zum Ausdruck bringen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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68. Öffentliche Hochschultagung der Agrar- und Ernährungswissenschaftlichen Fakultät der Uni Kiel

01. Feb. 2018

Landwirtschaftliche Betriebe müssen heutzutage verschiedensten Aufgaben nachkommen. Grundsätzlich versorgen sie die Bevölkerung mit Nahrungsmitteln. Hinzu kommen gesellschaftliche sowie politische Anforderungen, die zum Beispiel die Schonung der Umwelt oder Tierwohl betreffen. Nicht zuletzt muss der Betrieb wirtschaftlich arbeiten. Diesem Spannungsfeld widmet sich die Hochschultagung der Agrar- und Ernährungswissenschaftliche Fakultät der Christian-Albrechts-Universität zu Kiel (CAU). (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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7 Jahre frühe Nutzenbewertung nach AMNOG – Verfahren und Ergebnisse

12. Jan. 2018

Am Donnerstag, 25. Januar 2018 referiert die Leiterin des Bonner Instituts für evidenzbasierte Positionierung im Gesundheitswesen, Prof. Dr. Eva Susanne Dietrich, von 18:00 bis 19:30 Uhr über die verschiedenen Perspektiven des Arzneimittelmarktneuordnungsgesetzes. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Aktuelle Höhepunkte und Perspektiven der astronautischen und robotischen Raumfahrt in Europa

01. Jan. 2018

Öffentlicher Abendvortrag des NAWI e.V. +++ Referent: Astronaut Dr. Thomas Reiter, European Space Agency (ESA), Darmstadt (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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