A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Can Neuroplasticity Make Brains Young Again

Neuroplasticity is the process where the brain changes itself to provide new capacities. It is how memory and learning works. The Holy Grail of neuroscience is to find ways to enhance the brain’s ability to provide new capacities. Recently, there was found a possible way to re open the windows of enhanced learning that…

(Mehr in: Jon Lieff, M.D.)

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Cancer news

How decision-making habits influence the breast cancer treatments women consider

15. Aug. 2017

A new study finds that more than half of women with early stage breast cancer considered an aggressive type of surgery to remove both breasts. The way women generally approach big decisions, combined with their values, impacts what breast cancer treatment they consider, the study also found. (Mehr in: Cancer News — ScienceDaily)

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Birth defects, cancer linked

15. Aug. 2017

Some children born with birth defects may be at increased risk for specific types of cancer, according to a new review. (Mehr in: Cancer News — ScienceDaily)

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Epigenetic drugs show promise as antivirals

15. Aug. 2017

Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a new study. The study demonstrated that histone methyltransferases EZH2/1 inhibitors, which are being used in cancer clinical trials, have activity against a variety of viruses, including herpes simplex virus (HSV). (Mehr in: Cancer News — ScienceDaily)

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Protein that inhibits the development of autoimmune diseases discovered

15. Aug. 2017

The immune system protects humans from threats such as, for example, disease-causing bacteria, and cancer as well. Yet if the system malfunctions, it can attack the body it is supposed to defend and cause autoimmune diseases such as type one diabetes mellitus or multiple sclerosis. Scientists have now demonstrated that the membrane protein Caveolin-1 plays a key role in immune responses that trigger this type of disease. (Mehr in: Cancer News — ScienceDaily)

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Does stronger initial response to cancer treatment predict longer overall survival?

15. Aug. 2017

It seems like such a simple question: Do patients whose tumors shrink more in response to targeted treatment go on to have better outcomes than patients whose tumors shrink less? But the implications of a recent study demonstrating this relationship are anything but simple and could influence both the design of future clinical trials and the goals of oncologists treating cancer. (Mehr in: Cancer News — ScienceDaily)

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Genome sequencing method can detect clinically relevant mutations using 5 CTCs

15. Aug. 2017

Whole genome sequencing using long fragment read (LFR), a technology that can analyze the entire genomic content of small numbers of cells, detected potentially targetable mutations using only five circulating tumor cells (CTCs) in a patient with metastatic breast cancer. (Mehr in: Cancer News — ScienceDaily)

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Skewing the aim of targeted cancer therapies

15. Aug. 2017

The aim of targeted gene-based cancer therapies could often be skewed from the start. A widespread concept about how cells produce proteins proved incorrect 62 percent of the time in a new study in ovarian cancer cells on the relationship between RNA and protein levels. (Mehr in: Cancer News — ScienceDaily)

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Cancer-fighting T cells are smarter, stronger than experts thought

14. Aug. 2017

It takes a minuscule amount of force to make T cells behave in the lab as they behave in the body. That finding is a leap in cancer therapy research. (Mehr in: Cancer News — ScienceDaily)

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Discovery of new prostate cancer biomarkers could improve precision therapy

14. Aug. 2017

A new cause of treatment resistance in prostate cancer has been uncovered by investigators. Their discovery also suggests ways to improve prostate cancer therapy. (Mehr in: Cancer News — ScienceDaily)

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Cancer detection with sugar molecules

14. Aug. 2017

Scientists have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner. (Mehr in: Cancer News — ScienceDaily)

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Breast cancer study in India shows how the country can avoid crisis

14. Aug. 2017

A new study examining breast cancer awareness in India has found that a lack of early diagnosis is leading the country towards an epidemic. They found that educating men could be key to encouraging women to seek help earlier. (Mehr in: Cancer News — ScienceDaily)

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Sweet! Sugar-coated probe yields better acid test

11. Aug. 2017

When our cells‘ acid-alkaline balance goes wrong, it can go wrong in a big way — think cancer and cystic fibrosis. New fluorescent probes make it easier to detect pH and sweetened the deal by adding sugar to his acid-sensitive probes, making them much friendlier to living tissue. (Mehr in: Cancer News — ScienceDaily)

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Critical insights into T-cell development

11. Aug. 2017

Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn’s Disease and rheumatoid arthritis. (Mehr in: Cancer News — ScienceDaily)

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A metabolic pathway that feeds liver cancer

10. Aug. 2017

A little-studied gene may explain how some liver cancer cells obtain the nutrition they need to proliferate, according to new research. (Mehr in: Cancer News — ScienceDaily)

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Checkpoint inhibitors fire up different types of T cells to attack tumors

10. Aug. 2017

Cancer immunotherapies that block two different checkpoints on T cells launch immune attacks on cancer by expanding distinct types of T cell that infiltrate tumors, researchers report. (Mehr in: Cancer News — ScienceDaily)

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Increased endometrial cancer rates found in women with high levels of cadmium

09. Aug. 2017

Through a five-year observational study, researchers found that women with increased levels of cadmium — a metal commonly found in foods such as kidneys, liver and shellfish as well as tobacco — also had an increased risk of endometrial cancer. It’s an observation the researchers hope could lead to new treatments or interventions to prevent the fourth most common cancer in women. (Mehr in: Cancer News — ScienceDaily)

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Researchers look to improve detection of skin cancer lacking pigment melanin

09. Aug. 2017

Key features linked to amelanotic melanoma, a form of skin cancer that lacks the brown or black color that stems from the pigment melanin, have been identified by a team of researchers. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

25. Wiss. Symposium für Psychotherapie: Veränderbarkeit – Ändern/Verändern/Anders am 13./14.10.2017

12. Aug. 2017

1992 wurde das Wissenschaftliche Symposium für Psychotherapie eingeführt. 25 Jahre später lädt die LWL-Universitätsklinik Bochum für Psychosomatische Medizin und Psychotherapie zu einem Jubiläumssymposium ein. Was hat sich verändert und welche Entwicklungen sind zu erwarten? Psychotherapie will ändern und stellt sich der Frage nach der Veränderbarkeit eines Menschen. Die Vorträge reichen von (epi)genetischen über soziologische, kulturelle bis hin zu psychotherapeutischen Themen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Bavarian Summer School 2017 – The Future of Health Care

24. Jul. 2017

From 24/07/ until 04/08/17 the first summer school organized by Study & Work International, an initiative of the Bavarian Association of Universities of Applied Sciences (UAS), takes place at the Lutheran UAS Nuremberg and the technical UAS OTH Amberg-Weiden.The Future of Health Care: New Concepts – New Technologies is the topic of this two-week interdisciplinary summer school for Bachelor’s students from the fields of health care as well as various engineering disciplines (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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15th EUROPEAN CONFERENCE ON ORGANIZED FILMS

08. Jul. 2017

The 15th European Conference on Organized Films (ECOF 15) adds to a successful series of conferences addressing latest findings and advances in the field of thin and ultrathin organic films as well as nanoscience and -technologies. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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14th Dortmund MST Conference – Individualized Healthcare Solutions

05. Jul. 2017

Embracing „Individualized Healthcare Solutions“, the 14th Dortmund MST Conference on July 5, 2017 will present microsystems, production processes and digital technologies for use in medical technology and healthcare. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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14. Dortmunder MST-Konferenz – Individualisierte Gesundheitslösungen

05. Jul. 2017

Unter dem Motto „Individualisierte Gesundheitslösungen“ präsentiert die 14. Dortmunder MST-Konferenz am 5. Juli 2017 Mikrosysteme, mikrotechnische Fertigungsverfahren und digitale Technologien für den Einsatz in der Medizintechnik und Gesundheitsversorgung. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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17th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery

02. Jun. 2017

Call for Abstracts (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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14. HepNet Symposium

02. Jun. 2017

Akkreditiert: mit 10 CME-Punkten von der Ärztekammer Niedersachsen mit 13 iCME-Punkten von der Akademie für Infektionsmedizin

Wissenschaftliche Leitung: Prof. Dr. med. Michael P. Manns, Hannover Prof. Dr. med. Stefan Zeuzem, Frankfurt Prof. Dr. med. Claus Niederau, Oberhausen Prof. Dr. med. Ulrike Protzer, München Prof. Dr. med. Peter Schirmacher, Heidelberg (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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