A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Latin-Americans with different Native-American ancestry show different health risks

A genetic study of Chileans finds Mapuche and Aymara ancestry linked to different diseases (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

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Cancer news

Study sheds light on how ovarian cancer spreads

27. Jun. 2017

A team of researchers is studying the molecular mechanisms by which ovarian cancer spreads — or metastasizes — to uncover new therapeutic opportunities. (Mehr in: Cancer News — ScienceDaily)

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Pathway to ‚rejuvenating‘ immune cells to fight cancers and infections

27. Jun. 2017

A new discovery of the mechanism of T cell exhaustion will lead to treatments to enhance immunotherapies against cancers and such viruses as HIV. (Mehr in: Cancer News — ScienceDaily)

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Thwarting metastasis by breaking cancer’s legs with gold rods

27. Jun. 2017

Your cancer has metastasized. No one wants to ever hear that. Now researchers have found a way to virtually halt cell migration, a key component in metastasis, in vitro, in human cells. In past in vivo studies in mice, treated cancer did not appear to recur. No significant side effects were observed. (Mehr in: Cancer News — ScienceDaily)

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Blocking cancer: Scientists find new way to combat disease

27. Jun. 2017

A newly developed compound shows promise for blocking cancer-causing proteins on a cellular level, outlines a new report. (Mehr in: Cancer News — ScienceDaily)

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Glycans as biomarkers for cancer?

26. Jun. 2017

Glycosylated proteins are often overexpressed in tumor cells and thus could serve as tumor markers, especially those with the interesting molecule sialic acid as their sugar moiety. Scientists now report on a bioorthogonal labeling test for sialylated glycoproteins based on a glycoproteomics approach. This assay not only assesses the level of sialylated glycans in the tumor cell membranes, but also identifies up- or downregulated proteins directly in the prostate cancer tissue. (Mehr in: Cancer News — ScienceDaily)

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Microscope can scan tumors during surgery and examine cancer biopsies in 3-D

26. Jun. 2017

A new microscope could provide accurate real-time results during cancer-removal surgeries, potentially eliminating the 20 to 40 percent of women who have to undergo multiple lumpectomy surgeries because cancerous breast tissue is missed the first time around. (Mehr in: Cancer News — ScienceDaily)

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Colon cancer: Greater surgical precision using robotic surgery

26. Jun. 2017

Up until now, the removal of bowel tumors in the lesser pelvis (rectal cancers) involved a major, generally invasive operation. This operation can now be done in a much gentler way using an innovative procedure, robotic surgery. Thanks to a better three-dimensional view of the operating area and robotic instruments that allow highly accurate surgery to be performed in the anatomically constricted space of the lesser pelvis, surgical trauma and incisions for the operation can be kept to a minimum, while, at the same time, achieving excellent surgical results. (Mehr in: Cancer News — ScienceDaily)

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Cancer hijacks natural cell process to survive

26. Jun. 2017

Cancer tumors manipulate a natural cell process to promote their survival suggesting that controlling this mechanism could stop progress of the disease, according to new research. (Mehr in: Cancer News — ScienceDaily)

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Combination approach improves power of new cancer therapy

26. Jun. 2017

An international research team has found a way to improve the anti-cancer effect of a new medicine class called ‚Smac mimetics.‘ (Mehr in: Cancer News — ScienceDaily)

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Mitochondria targeting anti-tumor compound

26. Jun. 2017

The compound folic acid-conjugated methyl-BETA-cyclodextrin (FA-M-BETA-CyD) has significant antitumor effects on folate receptor-ALPHA-expressing (FR-ALPHA (+)) cancer cells, researchers have found. The compound significantly reduced ATP production while simultaneously increased the production of reactive oxygen species. Side effects in animal models were minimal but further testing is still required to determine its safety. (Mehr in: Cancer News — ScienceDaily)

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MRI without contrast agents? Yes, with sugar

23. Jun. 2017

Scientists have been able to visualize brain cancer using a novel MRI method. They use a simple sugar solution instead of conventional contrast agents, which can have side effects in the body. (Mehr in: Cancer News — ScienceDaily)

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Combined molecular biology test is the first to distinguish benign pancreatic lesions

23. Jun. 2017

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign. The lesions almost never progress to cancer, so patients may be spared unnecessary pancreatic cancer screenings or operations. The two-test combination is the only one to date that can accurately and specifically identify these benign pancreatic lesions. (Mehr in: Cancer News — ScienceDaily)

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Existing drugs could benefit patients with bone cancer, genetic study suggests

23. Jun. 2017

A subgroup of patients with osteosarcoma — a form of bone cancer — could be helped by an existing drug, suggest scientists. In the largest genetic sequencing study of osteosarcoma to date, scientists discovered that 10 percent of patients with a genetic mutation in particular growth factor signalling genes may benefit from existing drugs, known as IGF1R inhibitors. (Mehr in: Cancer News — ScienceDaily)

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A unique amino acid for brain cancer therapy

23. Jun. 2017

Photodynamic therapy is often used to treat brain tumors because of its specificity — it can target very small regions containing cancerous cells while sparing the normal cells around it from damage. It works by injecting a drug called a photosensitizer into the bloodstream, where it gathers in cells, and then exposing the drug-filled cells to light. When the photosensitizer is exposed to this light, it emits what is known as a reactive oxygen species (ROS) that causes the cells to die. (Mehr in: Cancer News — ScienceDaily)

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Tiny nanoparticles offer significant potential in detecting, treating disease new review of work on exosomes

22. Jun. 2017

Exosomes – tiny biological nanoparticles which transfer information between cells – offer significant potential in detecting and treating disease, the most comprehensive overview so far of research in the field has concluded. Areas which could benefit include cancer treatment and regenerative medicine. (Mehr in: Cancer News — ScienceDaily)

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A rising star: Researchers dissect the process by which blood vessels shrink, which could have important implications for human health

22. Jun. 2017

It’s a tiny marine invertebrate, no more than 3 millimeters in size. But closely related to humans, Botryllus schlosseri might hold the key to new treatments for cancer and a host of vascular diseases. (Mehr in: Cancer News — ScienceDaily)

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Similarities between next-generation prostate cancer drugs discovered

22. Jun. 2017

For the first time, researchers have shown how a class of advanced prostate cancer drugs are processed in the body and how their anti-tumor activity might change depending on how they are metabolized. Their pre-clinical findings may lay the foundation for improving therapies for treatment-resistant, aggressive prostate cancer. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

14. HepNet Symposium

02. Jun. 2017

Akkreditiert: mit 10 CME-Punkten von der Ärztekammer Niedersachsen mit 13 iCME-Punkten von der Akademie für Infektionsmedizin

Wissenschaftliche Leitung: Prof. Dr. med. Michael P. Manns, Hannover Prof. Dr. med. Stefan Zeuzem, Frankfurt Prof. Dr. med. Claus Niederau, Oberhausen Prof. Dr. med. Ulrike Protzer, München Prof. Dr. med. Peter Schirmacher, Heidelberg (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Art / Nature:Contemporary Art in Natural History Museums and Collections

02. Jun. 2017

A pilot project in cooperation with the German Federal Cultural Foundation.

The conference outlines recent and ongoing art projects and art programmes in natural history museums and in the natural history collections of multidisciplinary museums. In doing so, it aims to reflect upon and discuss the expectations, potentials, possible limitations and values of these kinds of interactions and interventions from the perspectives of curators, artists and researchers. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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8th Mildred Scheel Cancer Conference

02. Jun. 2017

Zum 8. Mal lädt die Deutsche Krebshilfe, gemeinsam mit der Deutschen Krebsgesellschaft, zur Mildred Scheel Cancer Conference ein. Vom 14.-16. Juni 2017 treffen sich renommierte Krebsexperten in Bonn, um über aktuelle Entwicklungen auf dem Gebiet der onkologischen Forschung zu diskutieren. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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8th International Triticeae Symposium 2017

02. Jun. 2017

This symposium includes four main themes:

Taxonomy, Phylogeny and Phytogeography Biodiversity and Conservation Genetics and Genomics Breeding and Utilization (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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8. Bayerischer Fachkongress Glücksspiel

02. Jun. 2017

Am 28. Juni 2017 findet der 8. Bayerische Fachkongress Glücksspiel im Novotel München City statt. Der Kongress läuft dieses Jahr unter dem Motto Migration – Trauma – Glücksspiel (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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7. HIPS Symposium on pharmaceutical sciences devoted to infection research

02. Jun. 2017

The HIPS symposium brings together renowed scientists and young investigators from three pharmaceutical communities: natural products, medicinal chemistry and drug delivery. It provides a forum for scientists to exchange ideas while crossing boundaries of classical disciplines. At the same time it gives young investigators the opportunity to obtain valuable feedback on their projects by international experts in the respective fields. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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3. Zukunftskongress "Technik zum Menschen bringen"

02. Jun. 2017

Der 3. Zukunftskongress „Technik zum Menschen bringen“ des Bundesministeriums für Bildung und Forschung findet vom 26. bis 27. Juni in Bonn (World Conference Center Bonn) statt. Diskutieren Sie mit uns gemeinsam neue Trends und informieren Sie sich über laufende und künftige Fördermaßnahmen des BMBF. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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