Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Hoffnung auf Netzhaut-Heilung: Blinde sollen wieder sehen

Keine Zeichnung, sondern ein scharfer Blick durchs Mikroskop auf die Retina mit Nervenfasern (blau) und Gefäßen.

Die Stammzellenforschung sorgt für Aufsehen: Abgestorbenes oder defektes Netzhautgewebe könnte durch reprogrammierte Körperzellen ersetzt werden.

(Mehr in: Medizin & Ernährung – FAZ.NET)

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Cancer news

Combined molecular biology test is the first to distinguish benign pancreatic lesions

23. Jun. 2017

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign. The lesions almost never progress to cancer, so patients may be spared unnecessary pancreatic cancer screenings or operations. The two-test combination is the only one to date that can accurately and specifically identify these benign pancreatic lesions. (Mehr in: Cancer News — ScienceDaily)

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Existing drugs could benefit patients with bone cancer, genetic study suggests

23. Jun. 2017

A subgroup of patients with osteosarcoma — a form of bone cancer — could be helped by an existing drug, suggest scientists. In the largest genetic sequencing study of osteosarcoma to date, scientists discovered that 10 percent of patients with a genetic mutation in particular growth factor signalling genes may benefit from existing drugs, known as IGF1R inhibitors. (Mehr in: Cancer News — ScienceDaily)

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A unique amino acid for brain cancer therapy

23. Jun. 2017

Photodynamic therapy is often used to treat brain tumors because of its specificity — it can target very small regions containing cancerous cells while sparing the normal cells around it from damage. It works by injecting a drug called a photosensitizer into the bloodstream, where it gathers in cells, and then exposing the drug-filled cells to light. When the photosensitizer is exposed to this light, it emits what is known as a reactive oxygen species (ROS) that causes the cells to die. (Mehr in: Cancer News — ScienceDaily)

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Tiny nanoparticles offer significant potential in detecting, treating disease new review of work on exosomes

22. Jun. 2017

Exosomes – tiny biological nanoparticles which transfer information between cells – offer significant potential in detecting and treating disease, the most comprehensive overview so far of research in the field has concluded. Areas which could benefit include cancer treatment and regenerative medicine. (Mehr in: Cancer News — ScienceDaily)

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A rising star: Researchers dissect the process by which blood vessels shrink, which could have important implications for human health

22. Jun. 2017

It’s a tiny marine invertebrate, no more than 3 millimeters in size. But closely related to humans, Botryllus schlosseri might hold the key to new treatments for cancer and a host of vascular diseases. (Mehr in: Cancer News — ScienceDaily)

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Similarities between next-generation prostate cancer drugs discovered

22. Jun. 2017

For the first time, researchers have shown how a class of advanced prostate cancer drugs are processed in the body and how their anti-tumor activity might change depending on how they are metabolized. Their pre-clinical findings may lay the foundation for improving therapies for treatment-resistant, aggressive prostate cancer. (Mehr in: Cancer News — ScienceDaily)

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Better use of current drugs to target cancer

22. Jun. 2017

Researchers worked backwards, employing a series of drugs used in the clinic to understand a new way that cancer stem cells can be killed. (Mehr in: Cancer News — ScienceDaily)

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An enzyme to synthetize carbohydrates designed

22. Jun. 2017

Sugar or carbohydrate synthesis is important for the development of diagnostic tests, vaccines and new drugs. In a study, researchers have synthesized carbohydrates with enzymes through a reaction that was not much studied so far on these biomolecules and which creates few by-products. (Mehr in: Cancer News — ScienceDaily)

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Flipping the switch to stop tumor development

22. Jun. 2017

Researchers show how a protein prevents the uncontrolled expansion of immune cells, and have outlined their findings in a new report. (Mehr in: Cancer News — ScienceDaily)

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Secondhand smoke exposure among nonsmoking adult cancer survivors has declined

22. Jun. 2017

From 1999/2000 to 2011/2012, exposure to secondhand smoke among nonsmoking adult cancer survivors declined from 39.6 percent to 15.7 percent, but rates of exposure were higher among those with a history of a smoking-related cancer and those living below the federal poverty level compared with those with other types of cancer and those with the highest incomes, respectively. (Mehr in: Cancer News — ScienceDaily)

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First-line immunotherapy treatment can improve survival for subset of lung cancer patients

22. Jun. 2017

Findings from a phase III clinical trial for advanced lung cancer patients could help oncologists better predict which patients are likely to receive the most benefit from immunotherapy as a first-line treatment based on the unique molecular characteristics of their tumor, according to a new study. (Mehr in: Cancer News — ScienceDaily)

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‚Rosetta Stone‘ to decode immune recognition

21. Jun. 2017

Medical researchers have developed an algorithm that predicts T cell recognition of antigens and sets the stage to more effectively harness the immune system. (Mehr in: Cancer News — ScienceDaily)

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Underused cancer test could improve treatment for thousands

21. Jun. 2017

A simple blood test could improve treatment for more than 1 in 6 stage 2 colon cancer patients, suggests new research. The researchers also discovered that many patients who could benefit from the test likely aren’t receiving it. (Mehr in: Cancer News — ScienceDaily)

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New antibody uses 1-2 punch to potentially treat blood cancers

21. Jun. 2017

Researchers have developed a two-pronged approach to blood cancer treatment: 1) attacking cancer cells directly and/or 2) driving them from the nurturing bone marrow environment into the peripheral blood streams, where they are more vulnerable (for example, to chemotherapy). (Mehr in: Cancer News — ScienceDaily)

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New inhibitor drug shows promise in relapsed leukemia

21. Jun. 2017

A new drug shows promise in its ability to target one of the most common and sinister mutations of acute myeloid leukemia (AML), according to researchers. In a first-in-human study, researchers treated relapsed patients with gilteritinib, an FLT3 inhibitor, and found it was a well-tolerated drug that led to frequent and more-sustained-than-expected clinical responses, almost exclusively in patients with this mutation. (Mehr in: Cancer News — ScienceDaily)

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New sensors could enable more affordable detection of pollution, diseases

21. Jun. 2017

When it comes to testing for cancer, environmental pollution and food contaminants, traditional sensors can help. The challenges are that they often are bulky, expensive, non-intuitive and complicated. Now, one team reports that portable pressure-based detectors coupled with smartphone software could provide a simpler, more affordable alternative while still maintaining sensitivity. (Mehr in: Cancer News — ScienceDaily)

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Finding the perfect match: New approach to battle drug-resistant bacteria

20. Jun. 2017

Antibiotics were the wonder drug of the 20th century, but bacteria evolved resistance. According to the CDC, more than 2 million people in the U.S. develop MDR infections every year. Researchers have now developed a rapid screen to pair existing FDA-approved drugs to combat MDR infections. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

7. HIPS Symposium on pharmaceutical sciences devoted to infection research

02. Jun. 2017

The HIPS symposium brings together renowed scientists and young investigators from three pharmaceutical communities: natural products, medicinal chemistry and drug delivery. It provides a forum for scientists to exchange ideas while crossing boundaries of classical disciplines. At the same time it gives young investigators the opportunity to obtain valuable feedback on their projects by international experts in the respective fields. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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3. Zukunftskongress "Technik zum Menschen bringen"

02. Jun. 2017

Der 3. Zukunftskongress „Technik zum Menschen bringen“ des Bundesministeriums für Bildung und Forschung findet vom 26. bis 27. Juni in Bonn (World Conference Center Bonn) statt. Diskutieren Sie mit uns gemeinsam neue Trends und informieren Sie sich über laufende und künftige Fördermaßnahmen des BMBF. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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37. Jahestagung Deutsche Gesellschaft für Senologie e.V.

02. Jun. 2017

Zur diesjährigen Jahrestagung der Deutschen Gesellschaft für Senologie e. V. (DGS) vom 29. Juni bis 1. Juli 2017 im CityCube Berlin werden wieder über 2500 Experten für Brusterkrankungen erwartet. Alle Experteninnen und Experten der verschiedenen Fachdisziplinen, die die Senologie vereint diskutieren auf den ca. 170 wissenschaftlichen Sitzungen, Kursen und Debatten gemeinsam über aktuelle Fragestellungen zur Früherkennung, Diagnostik, Therapie und Nachsorge von Brusterkrankungen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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2. Praxis-Workshop "Notfallmedizin für Ingenieure"

02. Jun. 2017

In der Notfallmedizin müssen Ärzte oftmals unter schwierigsten Umgebungsbedingungen und in kurzer Zeit valide Diagnosen stellen. Dafür ist eine verlässliche und gut zu bedienende Medizintechnik unerlässlich. Aber auch in diesem interdisziplinären Teilgebiet der Medizin werden sich technische Innovationen nur durchsetzen, wenn diese perfekt auf die Bedürfnisse der Betreiber und Anwender abgestimmt sind. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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17th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery

02. Jun. 2017

Call for Abstracts (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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14. HepNet Symposium

02. Jun. 2017

Akkreditiert: mit 10 CME-Punkten von der Ärztekammer Niedersachsen mit 13 iCME-Punkten von der Akademie für Infektionsmedizin

Wissenschaftliche Leitung: Prof. Dr. med. Michael P. Manns, Hannover Prof. Dr. med. Stefan Zeuzem, Frankfurt Prof. Dr. med. Claus Niederau, Oberhausen Prof. Dr. med. Ulrike Protzer, München Prof. Dr. med. Peter Schirmacher, Heidelberg (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Art / Nature:Contemporary Art in Natural History Museums and Collections

02. Jun. 2017

A pilot project in cooperation with the German Federal Cultural Foundation.

The conference outlines recent and ongoing art projects and art programmes in natural history museums and in the natural history collections of multidisciplinary museums. In doing so, it aims to reflect upon and discuss the expectations, potentials, possible limitations and values of these kinds of interactions and interventions from the perspectives of curators, artists and researchers. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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