About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Longer disease-free survival in phase III trial of sunitinib as adjuvant treatment for kidney cancer

A phase III trial of sunitinib has met its primary endpoint of disease-free survival for adjuvant treatment of high-risk renal cell carcinoma after nephrectomy, researchers report. (Mehr in: Cancer News — ScienceDaily)

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Cancer news

Critical step in DNA repair, cellular aging pinpointed

23. Mrz. 2017

The body’s ability to repair DNA damage declines with age, which causes gradual cell demise, overall bodily degeneration and greater susceptibility to cancer. Now, research reveals a critical step in a molecular chain of events that allows cells to mend their broken DNA. (Mehr in: Cancer News — ScienceDaily)

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Most cancer mutations are due to random DNA copying ‚mistakes‘

23. Mrz. 2017

Scientists report data from a new study providing evidence that random, unpredictable DNA copying ‚mistakes‘ account for nearly two-thirds of the mutations that cause cancer. Their research is grounded on a novel mathematical model based on DNA sequencing and epidemiologic data from around the world. (Mehr in: Cancer News — ScienceDaily)

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Researchers find another immune system link science said didn’t exist

23. Mrz. 2017

A part of the body thought to be disconnected from the immune system actually interacts with it, report investigators, and that discovery helps explain cases of male infertility, certain autoimmune diseases and even the failure of cancer vaccines. (Mehr in: Cancer News — ScienceDaily)

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First mutations in human life discovered

22. Mrz. 2017

The earliest mutations of human life have been observed by researchers. Analyzing genomes from adult cells, the scientists could look back in time to reveal how each embryo developed. The study shows that from the two-cell stage of the human embryo, one of these cells becomes more dominant than the other and leads to a higher proportion of the adult body. (Mehr in: Cancer News — ScienceDaily)

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Mapping the future of precision medicine in Parkinson’s disease

22. Mrz. 2017

A new transformative approach to defining, studying and treating Parkinson’s disease has been revealed by investigators. Rather than approaching Parkinson’s disease as a single entity, the international cadre of researchers advocates targeting therapies to distinct ‚nodes or clusters‘ of patients based on specific symptoms or molecular features of their disease. (Mehr in: Cancer News — ScienceDaily)

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‚First in human‘ trial defines safe dosage for small molecule drug ONC201 for solid cancer tumors

22. Mrz. 2017

A ‘first in human’ clinical trial examining the small molecule drug ONC201 in cancer patients with advanced solid tumors shows that this investigational drug is well tolerated at the recommended phase II dose. That’s according to investigators whose research also showed early signs of clinical benefit in patients with advanced prostate and endometrial cancers. (Mehr in: Cancer News — ScienceDaily)

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How do metals interact with DNA?

22. Mrz. 2017

Since a couple of decades, metal-containing drugs have been successfully used to fight against certain types of cancer. The lack of knowledge about the underlying molecular mechanisms slows down the search for new and more efficient chemotherapeutic agents. Scientists have now developed a protocol that is able to detect how metal-based drugs interact with DNA. (Mehr in: Cancer News — ScienceDaily)

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After the epigenome: The epitranscriptome

22. Mrz. 2017

A new article explains that RNA also has its own spelling and grammar, just like DNA. These ‚epigenetics of RNA‘ are called epitranscriptome. (Mehr in: Cancer News — ScienceDaily)

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Non-invasive prostate cancer diagnosing, monitoring

22. Mrz. 2017

Technology under development will provide a non-invasive approach for diagnosing prostate cancer and tracking the disease’s progression. It could enable doctors to determine how cancer patients are responding to different treatments without needing to perform invasive biopsies. (Mehr in: Cancer News — ScienceDaily)

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Significant increase in number of women tested for BRCA gene, but many high-risk patients still missing out

22. Mrz. 2017

Previously, mainly women with a history of cancer were referred for genetic testing, but as awareness has grown, more low-risk women are undergoing BRCA testing. A new study found that the proportion of women without a history of cancer who underwent BRCA testing rose sharply from 24.3% in 2004 to 61.5% in 2014. (Mehr in: Cancer News — ScienceDaily)

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Producing radioisotopes for medical imaging, disease treatment

21. Mrz. 2017

Accelerators built to explore the building blocks of matter help to feed the nation’s need for certain critical radioisotopes used to diagnose, track, and treat disease. (Mehr in: Cancer News — ScienceDaily)

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New Insights Into Side Effects Can Help Prostate Cancer Patients Choose Treatments

21. Mrz. 2017

A new study identifies distinct patterns of side effects for prostate cancer treatments that patients could use to guide their choices. (Mehr in: Cancer News — ScienceDaily)

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Caution needed for drugs in development for most common malignant pediatric brain tumor

21. Mrz. 2017

Researchers have studied how a crucial cancer-related protein plays a role in one of the most aggressive forms of medulloblastoma, the most common malignant brain tumor of childhood. (Mehr in: Cancer News — ScienceDaily)

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AML study correlates gene mutations with 34 disease subgroups

21. Mrz. 2017

A large, new study of adults with acute myeloid leukemia (AML) correlates 80 cancer-related gene mutations with five subtypes of AML, which are defined by the presence of specific chromosomal abnormalities. The findings might help guide mutation testing and treatment decisions in the future. (Mehr in: Cancer News — ScienceDaily)

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Structural knowledge of the DNA repair complex

21. Mrz. 2017

New research provides mechanistic insight into how DNA is monitored and repaired if damage occurs. The results may eventually help to improve the treatment of certain types of cancer, as the DNA repair complex provides a mechanism for cancer cells to resist chemotherapy. (Mehr in: Cancer News — ScienceDaily)

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Detecting and monitoring a patient’s cancer with a simple blood test?

20. Mrz. 2017

A series of proteins in blood plasma has now been identified that, when elevated, signify that the patient has cancer. This discovery, say researchers, may lead to a blood test that can detect and evaluate cancer in patients. (Mehr in: Cancer News — ScienceDaily)

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Single-cell analysis reveals subtypes of colorectal tumors

20. Mrz. 2017

Combining single-cell genomics and computational techniques medical researchers have defined cell-type composition of cancerous cells from 11 colorectal tumors, as well as adjacent noncancerous cells, a key to more targeted diagnosis and treatment. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

58. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin

02. Mrz. 2017

Von Atemnot bis hin zur künstlichen Beatmung – viele Lungenerkrankungen sind chronisch und mit einem hohen Leidensdruck für die Patienten verbunden. Die Sparpolitik des Gesundheitssystems macht es immer schwerer Patienten optimal zu betreuen. Viele Kliniken stehen unter Druck, kostendeckend zu arbeiten. Unter dem Motto „Qualität und Wirtschaftlichkeit“ diskutieren Experten wie die Versorgungsqualität trotz des finanziellen Drucks bestmöglich erhalten werden kann. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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43. Freiburger Infrarot-Kolloquium am Fraunhofer IAF

02. Mrz. 2017

Infrarottechnologie – Schlüsseltechnologie für Sicherheit, Medizin, Astronomie und Industrie.

Vom 14. – 15. März 2017 bietet das 43. Freiburg Infrarot-Kolloquium Experten der Infrarot-Technologie eine renommierte, internationale Plattform. Wissenschaftler, Ingenieure und Anwender von Infrarot-Detektoren, -Lasern und -Systemen sind eingeladen, sich über den neuesten Stand der Technik zu informieren und aktuelle Entwicklungen vorzustellen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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3. Interdisziplinärer Kongress "Quality of Cancer Care"

02. Mrz. 2017

Gemeinsam mit der Arbeitsgemeinschaft Deutscher Tumorzentren (ADT) lädt die Deutsche Krebsgesellschaft zum dritten Mal zum Kongress „Quality of Cancer Care“ (QoCC). Die Idee zu diesem Kongress entstand aus der Erfahrung, dass es häufig die Schnittstellen sind, an denen es in der Qualitätsentwicklung der Krebsversorgung zu Reibungsverlusten kommt. Der QoCC 2017 steht unter dem Motto „Qualität in der Patientenversorgung“. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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2. INTERBILD – INTERDISZIPLINÄRES SYMPOSIUM – BILDSCHIRMARBEIT

02. Mrz. 2017

Displays von Smartphone, Tablet und PC dominieren unsere Freizeit und Arbeitswelt. Einerseits ist das eine oder andere mit ihnen angenehmer und komfortabler, anderseits entstehen neue gesundheitliche Probleme. Um dies fachgerecht zu erfassen und zu verstehen, zu diagnostizieren und zu therapieren, ist interdisziplinäres Denken und Handeln wichtig. Das 2. Symposium INTERBILD richtet sich erneut an alle Fachdisziplinen in Praxis und Forschung, die sich mit dem Thema „Bildschirmarbeit“ befassen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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17. Patientenforum Lunge

02. Mrz. 2017

Am 25. März 2017 lädt der Lungeninformationsdienst gemeinsam mit dem Deutschen Zentrum für Lungenforschung (DZL) und dem Deutschen Lungentag herzlich zum 17. Patientenforum Lunge nach Stuttgart ein. Das Thema: „Aktuelles zu klinischen Studien in der Lungenforschung – Wie nützen sie den Patienten?“ (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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13th German Peptide Symposium

02. Mrz. 2017

The Symposium will cover all areas of peptide science, including peptide chemistry, biochemistry, biophysics, structural biology, immunology, pharmacology, as well as the use of peptides in medicine and material sciences. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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12. ThGOT Thementage Grenz- und Oberflächentechnik mit 5. Kolloquium Dünne Schichten in der Optik

02. Mrz. 2017

Die 12. Thementage Grenz- und Oberflächentechnik und das 5. Kolloquium Dünne Schichten in der Optik fnden vom 14. – 16. März 2017 im Bio-Seehotel Zeulenroda in Thüringen statt. Die Tagung richtet sich an Vertreter aus Wissenschaft und Wirtschaft, die sich einen akteullen Überblick über die Querschnittstechnologie OBERFLÄCHENTECHNIK verschaffen wollen. Regelmäßig nehmen etwa 200-250 Besucher an der deutschsprachigen Konferenz mit Poster- und Industrieausstellung teil. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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