About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Biomedizin-Förderpreis: Von der Krebsforschung zur Augenheilkunde

In der Biomedizin werden Grundlagen für neue Medikamente und Therapieansätze erforscht: Zur Unterstützung des Forschungsschwerpunkts in Dortmund hat der Verein zur Förderung der biomedizinischen und klinischen Forschung am 28. September den mit insgesamt 3000 Euro dotierten Biomedizin-Förderpreis an vier Forscher verliehen. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

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Cancer news

MicroRNA could help treat cancer and asthma

20. Feb. 2018

A microRNA that regulates inflammation shows promise as a treatment for inflammatory diseases such as asthma and cancer, according to new research. (Mehr in: Cancer News — ScienceDaily)

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‚Icebreaker‘ protein opens genome for T-cell development, researchers find

20. Feb. 2018

Researchers describe the role of a transcription factor called TCF-1 in targeting the condensed chromatin and regulating the availability of genome sequences in T-cell development. The new connection between TCF-1 and chromatin will aid in developing new therapies using epigenetic drugs to alter T-cell fate in cancer, autoimmune disorders, and infectious diseases. (Mehr in: Cancer News — ScienceDaily)

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‚Click chemistry‘ reactions may boost cancer-fighting drug potency

20. Feb. 2018

Researchers have developed a quick and easy way to simultaneously modify dozens of drugs or molecules to improve their disease-fighting properties. (Mehr in: Cancer News — ScienceDaily)

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Genes activated in metastasis also drive the first stages of tumor growth

20. Feb. 2018

Researchers have demonstrated that genes activated during metastasis are also able to initiate primary tumor development, and they explain the molecular mechanism involved. (Mehr in: Cancer News — ScienceDaily)

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Nitrate in drinking water increases the risk of colorectal cancer, study finds

20. Feb. 2018

Nitrate in groundwater and drinking water, which primarily comes from fertilisers used in the agricultural production, has not only been subject to decades of environmental awareness — it has also been suspected of increasing the risk of cancer. The largest epidemiological study ever carried out in this area now shows that there is a correlation — also when the amount of nitrate in the drinking water is far below the current drinking water standard. (Mehr in: Cancer News — ScienceDaily)

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Some viruses produce insulin-like hormones that can stimulate human cells — and have potential to cause disease

19. Feb. 2018

Scientists have identified four viruses that can produce insulin-like hormones that are active on human cells. The discovery brings new possibilities for revealing biological mechanisms that may cause diabetes or cancer. (Mehr in: Cancer News — ScienceDaily)

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Novel mechanism linking changes in mitochondria to cancer cell death

19. Feb. 2018

Researchers have discovered that the activation of a specific enzyme may help suppress the spread of tumors. (Mehr in: Cancer News — ScienceDaily)

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Flexible warped nanographene developed for bioimaging

19. Feb. 2018

An international team of scientists has developed a water-soluble „warped nanographene,“ a flexible molecule that is biocompatible and shows promise for fluorescent cell imaging. The new nanographene molecule also induces cell death when exposed to blue laser light. Further investigation is required to determine how nanocarbons could be used for a range of biological applications, such as photodynamic therapy for cancer treatments. (Mehr in: Cancer News — ScienceDaily)

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How the insulin receptor works

19. Feb. 2018

As we are approaching the 100th anniversary of the discovery of insulin, a wide array of its signaling pathways has been defined. However, the initial step in insulin action, i.e. the engagement with its cell-surface receptor and the resulting conformational change, which propagates across the plasma membrane to the intracellular module, remains poorly understood. (Mehr in: Cancer News — ScienceDaily)

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Studying mitosis‘ structure to understand the inside of cancer cells

18. Feb. 2018

Cell division is an intricately choreographed ballet of proteins and molecules that divide the cell. During mitosis, microtubule-organizing centers assemble the spindle fibers that separate the copying chromosomes of DNA. While scientists are familiar with MTOCs‘ existence and the role they play in cell division, their actual physical structure remains poorly understood. Researchers are now trying to decipher their molecular architecture. (Mehr in: Cancer News — ScienceDaily)

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Ras protein’s role in spreading cancer

18. Feb. 2018

Protein systems make up the complex signaling pathways that control whether a cell divides or, in some cases, metastasizes. Ras proteins have long been the focus of cancer research because of their role as ‚on/off switch‘ signaling pathways that control cell division and failure to die like healthy cells do. Now, a team of researchers has been able to study precisely how Ras proteins interact with cell membrane surfaces. (Mehr in: Cancer News — ScienceDaily)

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Increasing incidence of rare skin cancer

16. Feb. 2018

While it may not be as common as other skin cancers, Merkel cell carcinoma is highly aggressive and often deadly — and according to new research, it’s also becoming more common. (Mehr in: Cancer News — ScienceDaily)

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Labs differ widely in BRCA testing protocols

15. Feb. 2018

A new article showcases the wide differences in BRCA testing protocols at labs around the world. The article surveyed 86 laboratories around the world about their BRCA testing practices and found that all the labs differed widely in their approach. (Mehr in: Cancer News — ScienceDaily)

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New mutation linked to ovarian cancer can be passed down through dad

15. Feb. 2018

A newly identified mutation, passed down through the X-chromosome, is linked to earlier onset of ovarian cancer in women and prostate cancer in father and sons. (Mehr in: Cancer News — ScienceDaily)

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CRISPR-based diagnostic tool advanced, miniature paper test developed

15. Feb. 2018

The team that first unveiled the rapid, inexpensive, highly sensitive CRISPR-based diagnostic tool called SHERLOCK has greatly enhanced the tool’s power to work with a miniature paper test, similar to a pregnancy test, allowing rapid and simple detection in any setting. Additional features greatly expand both the breadth and sensitivity of the diagnostic information, including the ability to detect multiple targets at once and quantify the amount of target in a sample. (Mehr in: Cancer News — ScienceDaily)

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How cancer cells repair themselves following proton beam therapy

15. Feb. 2018

New research identifies the specific cellular process that helps cancer cells damaged as a result of proton beam therapy, repair themselves. (Mehr in: Cancer News — ScienceDaily)

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Working in harmony: New insights into how packages of DNA orchestrate development

15. Feb. 2018

New research illuminates aspects of how an early embryo, the product of fertilization of a female egg cell by a male sperm cell, can give rise to all the many cell types of the adult animal. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

3. Bucerius-Medizinrechtstag "Schnittstellenprobleme des Medizinrechts"

13. Feb. 2018

Eröffnung des Instituts für Medizinrecht an der Bucerius Law School (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Arbeitstagung NeuroIntensivmedizin (ANIM) 2018

01. Feb. 2018

Die ANIM 2018 ist die 35. Jahrestagung der Deutschen Gesellschaft für NeuroIntensiv- und Notfallmedizin und der Deutschen Schlaganfall-Gesellschaft und findet vom 8.–10. Februar 2018 in Würzburg statt. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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ADDITIVE FERTIGUNG – fokus: kunststoff

01. Feb. 2018

Schwerpunktthemen: • Innovationen für Material, Verfahren und Prozesse • Best-Practice-Lösungen für Consumer, Automotive und Medical • Konstruktion und Simulation neu gedacht • Betriebsfestigkeit, Sicherheit und Zuverlässigkeit • Qualifizierung, Zertifizierung und Zulassung (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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78. Jahrestagung der Deutschen Geophysikalischen Gesellschaft

01. Feb. 2018

Die Deutsche Geophysikalische Gesellschaft (DGG) veranstaltet jährlich eine große Fachtagung. Im Jahr 2018 erfolgt die Jahrestagung gemeinsam mit der Österreichischen Geophysikalischen Gesellschaft (Austrian Geophysical Society, AGS) in Leoben. Damit wollen die Gesellschaften in besonderem Maße ihr Interesse an internationalem Austausch und Zusammenarbeit zum Ausdruck bringen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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68. Öffentliche Hochschultagung der Agrar- und Ernährungswissenschaftlichen Fakultät der Uni Kiel

01. Feb. 2018

Landwirtschaftliche Betriebe müssen heutzutage verschiedensten Aufgaben nachkommen. Grundsätzlich versorgen sie die Bevölkerung mit Nahrungsmitteln. Hinzu kommen gesellschaftliche sowie politische Anforderungen, die zum Beispiel die Schonung der Umwelt oder Tierwohl betreffen. Nicht zuletzt muss der Betrieb wirtschaftlich arbeiten. Diesem Spannungsfeld widmet sich die Hochschultagung der Agrar- und Ernährungswissenschaftliche Fakultät der Christian-Albrechts-Universität zu Kiel (CAU). (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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7 Jahre frühe Nutzenbewertung nach AMNOG – Verfahren und Ergebnisse

12. Jan. 2018

Am Donnerstag, 25. Januar 2018 referiert die Leiterin des Bonner Instituts für evidenzbasierte Positionierung im Gesundheitswesen, Prof. Dr. Eva Susanne Dietrich, von 18:00 bis 19:30 Uhr über die verschiedenen Perspektiven des Arzneimittelmarktneuordnungsgesetzes. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Aktuelle Höhepunkte und Perspektiven der astronautischen und robotischen Raumfahrt in Europa

01. Jan. 2018

Öffentlicher Abendvortrag des NAWI e.V. +++ Referent: Astronaut Dr. Thomas Reiter, European Space Agency (ESA), Darmstadt (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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