Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Studie: Weniger Lebenszufriedenheit nach Jobverlust, emotionales Wohlbefinden erholt sich

Wissenschaftler der Freien Universität Berlin und des DIW Berlin untersuchen differenziert die Gefühlslagen von Arbeitslosen: Auch lange Zeit nach einem Jobverlust erreichen Arbeitslose einer Studie zufolge nicht wieder das Niveau an Lebenszufriedenheit, auf dem sie sich vor der Arbeitslosigkeit befunden haben. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

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Cancer news

Novel ‚barcode‘ tracking of T cells in immunotherapy patients identifies likely cancer-killers

24. Feb. 2017

A new discovery makes an important step in identifying which specific T cells within the diverse army of a person’s immune system are best suited to fight cancer. (Mehr in: Cancer News — ScienceDaily)

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New structural studies reveal workings of a molecular pump that ejects cancer drugs

24. Feb. 2017

Sometimes cells spit out things we don’t want them to — like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs. (Mehr in: Cancer News — ScienceDaily)

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Gene mutations cause leukemia, but which ones?

23. Feb. 2017

New research sought to better understand one ‚typo‘ in a standard leukemia assay, or test. The study, however, encountered a new problem: an issue with the model system itself. (Mehr in: Cancer News — ScienceDaily)

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Why is pancreatic cancer so hard to treat? Stroma provides new clues

23. Feb. 2017

Why are pancreatic tumors so resistant to treatment? One reason is that the ‚wound‘-like tissue that surrounds the tumors, called stroma, is so dense, likely preventing cancer-killing drugs from reaching the tumor. A team has now discovered heterogeneity in the fibroblast portion of the stroma, opening up the possibility of targeted treatment. (Mehr in: Cancer News — ScienceDaily)

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Tumor protein could hold key to pancreatic cancer survival

23. Feb. 2017

A diagnosis of pancreatic cancer is often a death sentence because current chemotherapies have little impact on the disease. In a new study, researchers were able to slow down growth and spread of tumors by targeting this protein in stellate cells in animal models, in combination with current chemotherapies. (Mehr in: Cancer News — ScienceDaily)

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Anti-aging gene identified as a promising therapeutic target for older melanoma patients

23. Feb. 2017

An anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved in metastatic progression and resistance to targeted therapies for the disease, new research indicates. (Mehr in: Cancer News — ScienceDaily)

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Direct-to-consumer genomics: Harmful or empowering?

23. Feb. 2017

In a new study, a research explores questions that stem from new advances in direct-to-consumer DNA tests, which have the effect of separating the physician-patient relationship from access to new personal health data. (Mehr in: Cancer News — ScienceDaily)

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Compounds that show potent anti-cancer activity in breast and colon tumor cell lines

23. Feb. 2017

Potential drugs have shown low toxicity in non-tumor cell lines, which could decrease side effects during chemotherapy, researchers suggest. (Mehr in: Cancer News — ScienceDaily)

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How blood can be rejuvenated

23. Feb. 2017

Our blood stem cells generate around a thousand billion new blood cells every day. But the blood stem cells’ capacity to produce blood changes as we age. This leads to older people being more susceptible to anemia, lowered immunity and a greater risk of developing certain kinds of blood cancer. Now for the first time, a research team has succeeded in rejuvenating blood stem cells with established reduced function in aging mice. (Mehr in: Cancer News — ScienceDaily)

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PI3K/mTOR inhibitors may be effective against some uterine sarcomas

23. Feb. 2017

The protein P-S6S240 may serve as an indicator of poor prognosis for patients with a hard-to-treat type of uterine sarcoma called leiomyosarcoma, and preclinical data suggest that patients whose tumors have this protein may respond to PI3K/mTOR inhibitors. (Mehr in: Cancer News — ScienceDaily)

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Measuring patients‘ muscles to predict chemotherapy side effects

22. Feb. 2017

Measuring patients‘ muscle mass and quality could potentially help doctors better identify patients at high risk for toxic side effects that could require hospitalizations, researchers report. (Mehr in: Cancer News — ScienceDaily)

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CAR T cells more powerful when built with CRISPR, researchers find

22. Feb. 2017

Researchers have harnessed the power of CRISPR/Cas9 to create more-potent chimeric antigen receptor (CAR) T cells that enhance tumor rejection in mice. (Mehr in: Cancer News — ScienceDaily)

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Using a rabbit virus to treat multiple myeloma

21. Feb. 2017

Treating multiple myeloma (MM) with myxoma virus (MYXV) eliminated a majority of malignant cells in preclinical studies, report investigators. Furthermore, introduction of MYXV had no impact on the bone marrow compartment and elicited a strong immune response that eradicated disease in some animals. (Mehr in: Cancer News — ScienceDaily)

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‚Sweet spot‘ where tissue stiffness drives cancer’s spread

21. Feb. 2017

Researchers have now found that physical forces exerted between cancer cells and the ECM are enough to drive a shape change necessary for metastasis. Those forces converge on an optimal stiffness that allows cancer cells to spread. (Mehr in: Cancer News — ScienceDaily)

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Prostate cancer cells grow with malfunction of cholesterol control in cells

21. Feb. 2017

Advanced prostate cancer and high blood cholesterol have long been known to be connected, but it has been a chicken-or-egg problem. Now a team of researchers has identified a cellular process that cancer cells hijack to hoard cholesterol and fuel their growth. Identifying this process could inform the development of better ways to control cholesterol accumulation in tumors, potentially leading to improved survival for prostate cancer patients. (Mehr in: Cancer News — ScienceDaily)

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The way breast cancer genes act could predict your treatment

21. Feb. 2017

Effective treatment options for breast cancer can be predicted based on the way certain breast cancer genes act or express themselves, a researcher has concluded. (Mehr in: Cancer News — ScienceDaily)

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New type of immunological treatment of cancer?

21. Feb. 2017

Researchers have found an important piece of the puzzle leading towards an understanding of how our innate immune system reacts against viral infections and recognises foreign DNA, for example from dying cancer cells. The discovery may prove to be of great importance for immunological treatment of cancer as well as autoimmune diseases in the future. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

Arbeitstagung NeuroIntensivMedizin ANIM 2017

01. Feb. 2017

2017 findet in Wien die 34. Jahrestagung der Deutschen Gesellschaft für NeuroIntensiv- und Notfallmedizin (DGNI) in Zusammenarbeit mit der Deutschen SchlaganfallGesellschaft (DSG) statt. Hier werden in einem breit gefächerten Programm für alle neurointensivmedizinisch interessierten Ärzte, Pflegekräfte und Therapeuten sowohl „klassische“ als auch kontroverse Themen der Neurointensivmedizin behandelt. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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2. Symposium "Digitale Menschmodelle in industriellen Anwendungen"

01. Feb. 2017

Dieses Symposium dient dem fachlichen Austausch zwischen Entwicklern und Nutzern von Digitalen Menschmodellen (DMM) in industriellen Anwendungen, wie beispielsweise Ergonomieuntersuchungen, Mensch-Roboter-Interaktionen und Arbeitsplatzsimulationen. Neben zahlreichen Fachvorträgen gibt es ausreichend Zeit für Diskussionen und den Austausch untereinander, um Anforderungen aus der Nutzersicht, aktuelle Limitierungen und neue Ansätze in Bereich der DMM zu behandeln. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Crash-Kurs Klinisches Risikomanagement und dessen Rahmenbedingungen

01. Feb. 2017

Das Seminar bietet Ihnen einen ersten Überblick über alle Aspekte des klinischen Risikomanagements sowie dessen Anforderungen an die daran angebundenen Technologien wie Medizintechnik, Informationstechnologie,Hygiene und Medikamentenmanagement. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Crash-Kurs Klinisches Risikomanagement und dessen Rahmenbedingungen

01. Feb. 2017

Die Patientenversorgung ist eine hoch risikobehaftete Aufgabe und erfordert größte Anstrengungen für ein risikobewußtes und achtsames Handeln. Nur dadurch kann Patientensicherheit so optimal wie möglich gewährleistet werden. Ein fundiertes Wissen über den effektiven Betrieb eines klinischen Risikomanagements verschafft Ihnen und allen Beteiligten mehr Sicherheit in der täglichen Arbeit. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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Best Practice Erfahrungsaustausch – Naturwissenschaft und Technik als Integrationsaspekt?

01. Feb. 2017

Gemeinsam mit dem Förderverein Science und Technologie e. V. möchte die Deutsche Physikalische Gesellschaft (DPG) Vertreterinnen und Vertreter aus Politik, Medien und Wissenschaft zu einem Erfahrungsaustausch an einen Tisch bringen, um den Aspekt des naturwissenschaftlichen Experimentierens als Werkzeug der Integration und der frühen Bildung näher zu beleuchten. Dabei werden Best-Practice-Beispiele vorgestellt. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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1st DZHK Conference on Translational Medicine

01. Jan. 2017

Wie kommt die Forschung zum Patienten? Darum geht es in der ersten DZHK-Konferenz im Januar 2017 in Berlin mit internationalen Experten aus verschiedenen medizinischen Fachrichtungen. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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5. Nationales Biobanken-Symposium 2016

01. Dez. 2016

Leitthema: Biobanken als Bindeglied zwischen Versorgung und Forschung – Call for Papers bis 01.07.2016 (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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