Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

Energy transfer in material solids is driven primarily by differences in intensive thermodynamic quantities such as pressure and temperature. The crucial observation  in quantum-theoretical models was the consideration of the heat capacity as associated with the vibrations of atoms in a crystalline

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A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming Wallace hypothesized mitochondrial dysfunction as a central role in a wide range of age-related disorders and various forms of cancer. Steadily rising increases in mitochondrial DNA mutations cause abr

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Wholeness and implicate order: “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior

Bohm used the term ‘holomovement’ which is an unbroken and undivided totality and carries an implicate order which is he totality of an order including both the manifested and non-manifested aspects of the order. Non-local quantum phenomena reside in a subtler level than quantum level that is th

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Mitochondria and the evolutionary roots of cancer

Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to in

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Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Tomasetti and Vogelstein show that the lifetime risk of cancers of many different types is strongly correlated with the total number of divisions of the normal self-renewing cells maintaining that tissue’s homeostasis. These results suggest that only a third of the variation in cancer risk among t

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Quantum entanglement between the electron clouds of nucleic acids in DNA

Rieper, Anders and Vedral modelled the electron clouds of nucleic acids in a single strand of DNA as a chain of coupled quantum harmonic oscillators with dipole-dipole interaction between nearest neighbours. As a main result, the entanglement contained in the chain coincides with the binding energy

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Quantum Teleportation and Von Neumann Entropy

From the aspect of the quantum information theories, various quantum entropies are possibly computed at each stage, which ensures the emergence of the entangled states in the intermediate step. If a single qubit quantum teleportation is near the computational basis, the quantum measurement is domina

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Quantum Tunnelling to the Origin and Evolution of Life

Quantum tunnelling is a phenomenon which becomes relevant at the nanoscale and below. It is a paradox from the classical point of view as it enables elementary particles and atoms to permeate an energetic barrier without the need for sufficient energy to overcome it. Tunnelling is being of vital imp

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

Low non-specific, low intensity laser illumination (635, 670 or 830 nm) apparently enhances centriole replication and promotes cell division, what is the opposite of a desired cancer therapy. In the contrary, centrioles are sensitive to coherent light. Then higher intensity laser illumination - stil

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About metabolism of a carcinoma cell

Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The alteration from oxidative phosphorylation to glycolysis – called the Warburg effect – is an universal phenomen and has now become a diagnostic tool for cancer detection. Warburg O, Posener K, Negelein E.

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Software hilft Embryonalentwicklung zu entschlüsseln

Bei jedem neuen Lebewesen wir aus einem winzigen Zellhaufen ein Organismus mit verschiedenen Körperteilen. Vor 60 Jahren proklamierte Alan Turing, dass dies durch die Ausbreitung zweier unterschiedlicher Signalmoleküle zwischen den Zellen gesteuert wird. Wissenschaftler vom Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft haben jetzt eine Software entwickelt, die mittels eines mathematischen Algorithmus solche Systeme mit mehr als zwei Molekülen analysieren kann. Mit der Software haben die Forscher Musterbildungsprozesse während der Embryonalentwicklung untersucht und können nun neue Systeme für den Einsatz in der Biotechnologie und regenerativen Medizin aufzeigen. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

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Cancer news

How obesity promotes breast cancer

20. Okt. 2017

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result. The research team has already been able to halt this mechanism with an antibody treatment. (Mehr in: Cancer News — ScienceDaily)

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Can an aspirin a day keep liver cancer away?

20. Okt. 2017

A new study found that daily aspirin therapy was significantly associated with a reduced risk in hepatitis B related liver cancer. (Mehr in: Cancer News — ScienceDaily)

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New function in gene-regulatory protein discovered

20. Okt. 2017

Researchers show how the protein CBP affects the expression of genes through its interaction with the basal machinery that reads the instructions in our DNA. (Mehr in: Cancer News — ScienceDaily)

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Gut bacteria from wild mice boost health in lab mice

19. Okt. 2017

Laboratory mice that are given the gut bacteria of wild mice can survive a deadly flu virus infection and fight colorectal cancer dramatically better than laboratory mice with their own gut bacteria, researchers report. (Mehr in: Cancer News — ScienceDaily)

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Gene circuit switches on inside cancer cells, triggers immune attack

19. Okt. 2017

Researchers have developed a synthetic gene circuit that triggers the body’s immune system to attack cancers when it detects signs of the disease. (Mehr in: Cancer News — ScienceDaily)

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One to 10 mutations are needed to drive cancer, scientists find

19. Okt. 2017

For the first time, scientists have provided unbiased estimates of the number of mutations needed for cancers to develop, in a study of more than 7,500 tumors across 29 cancer types. Researchers have adapted a technique from the field of evolution to confirm that, on average, one to ten driver mutations are needed for cancer to emerge. (Mehr in: Cancer News — ScienceDaily)

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Gut bacterium indirectly causes symptoms by altering fruit fly microbiome

19. Okt. 2017

CagA, a protein produced by the bacterium Helicobacter pylori, can alter the population of microbes living in the fruit fly gut, leading to disease symptoms, according to new research. (Mehr in: Cancer News — ScienceDaily)

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New machine learning system can automatically identify shapes of red blood cells

19. Okt. 2017

Using a computational approach known as deep learning, scientists have developed a new system to classify the shapes of red blood cells in a patient’s blood. The findings, published in PLOS Computational Biology, could potentially help doctors monitor people with sickle cell disease. (Mehr in: Cancer News — ScienceDaily)

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Fundamental research enhances understanding of major cancer gene

19. Okt. 2017

Scientists have provided new insights into the role of PTEN, a major cancer gene, in controlling cell growth and behavior. PTEN is the second most commonly altered gene in human cancers, particularly prostate cancers, and this work could help to develop and target new treatments. (Mehr in: Cancer News — ScienceDaily)

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Key molecular link in major cell growth pathway

19. Okt. 2017

A team of scientists has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth. The researchers‘ findings also implicate a new protein, SLC38A9, as a potential drug target in pancreatic cancer. (Mehr in: Cancer News — ScienceDaily)

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New findings explain how UV rays trigger skin cancer

18. Okt. 2017

Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the US in 2017, according to the Centers for Disease Control and Prevention. A fraction of those melanomas come from pre-existing moles, but the majority of them come from sources unknown — until now. (Mehr in: Cancer News — ScienceDaily)

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Researchers release the brakes on the immune system

18. Okt. 2017

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural “brakes” in the immune defense mechanism, which normally prevent an excessive immune response. Researchers have now been able to take off one of these brakes. The study could pave the way for more effective cancer therapies, they say. (Mehr in: Cancer News — ScienceDaily)

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Yeast spotlights genetic variation’s link to drug resistance

18. Okt. 2017

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists show that high genetic diversity can prime new mutations that cause drug resistance. The study has implications for our understanding of the evolution of resistance to antimicrobial and anticancer drugs. (Mehr in: Cancer News — ScienceDaily)

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Battling flames increases firefighters‘ exposure to carcinogens

18. Okt. 2017

The threat of getting burned by roaring flames is an obvious danger of firefighting, but other health risks are more subtle. For example, firefighters have been found to develop cancer at higher rates than the general population. Now researchers have measured how much firefighters‘ exposure to carcinogens and other harmful compounds increases when fighting fires. Their study also points to one possible way to reduce that exposure. (Mehr in: Cancer News — ScienceDaily)

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Machine learning identifies breast lesions likely to become cancer

18. Okt. 2017

A machine learning tool can help identify which high-risk breast lesions are likely to become cancerous, according to a new study. Researchers said the technology has the potential to reduce unnecessary surgeries. (Mehr in: Cancer News — ScienceDaily)

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Therapeutic form of arsenic is a potential treatment for deadly type of brain cancer

17. Okt. 2017

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element may be a potent force against cancer. (Mehr in: Cancer News — ScienceDaily)

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Cancer: New compound targets energy generation, thereby killing metastatic cells

17. Okt. 2017

Researchers have identified an enzyme that supports the survival and dissemination of metastatic cells, and developed a synthetic compound that targets the enzyme and kills the metastatic cells in mice with cancer. (Mehr in: Cancer News — ScienceDaily)

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Veranstaltungen

17. Wissenschaftliche Jahrestagung der DGSF

01. Okt. 2017

Von der Neutralität zur Parteilichkeit – SystemikerInnen mischen sich ein (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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16. Deutscher Kongress für Versorgungsforschung

01. Okt. 2017

Unter dem Thema: „Zukunft Regionale Versorgung – Forschung, Innovation, Kooperation“ wird vom 4. bis 6. Oktober 2017 der 16. Deutsche Kongress für Versorgungsforschung (DKVF2016) in der Urania in Berlin stattfinden. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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100 Jahre Zukunft. Die Mistel in der Krebstherapie

01. Okt. 2017

Die Misteltherapie – immer noch umstritten oder längst etabliert? Antworten auf diese Frage gibt es beim Symposium „100 Jahre Zukunft. Die Mistel in der Krebstherapie“ am 21. Oktober 2017 in Berlin. Das Symposium richtet sich an Ärzte, Pharmazeuten, Therapeuten, Pflegende und Patienten. Theorie und Praxis kommen gleichermaßen zu Wort: Best-Practice, Erfahrungen und spannende Forschungsergebnisse werden vorgestellt. Diskussionen und Roundtables ergänzen das Programm. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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100 Jahre Max-Planck-Institut für Physik – Jubiläumssymposium und Festakt

01. Okt. 2017

Das Max-Planck-Institut für Physik begeht seinen 100. Jahrestag: Am 1. Oktober 1917 nahm das damalige Kaiser-Wilhelm-Institut für Physik unter Direktor Albert Einstein seine Arbeit auf. Dieses Jubiläum feiert das MPI für Physik mit einem wissenschaftlichen Symposium, das vom 10. bis 12. Oktober 2017 stattfindet. Ein anschließender Festakt mit Abendprogramm beschließt die Feierlichkeiten zum 100-jährigen Bestehen des Instituts. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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1st Gießen Symposium of Insect Biotechnology

01. Okt. 2017

We are delighted to invite delegates to the 1st Gießen Symposium for Insect Biotechnology. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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19th Herbstakademie

01. Okt. 2017

Embodied Aesthetics: Resonance in Perception, Expression and Therapy (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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22. International Biohydrometallurgy Symposium

01. Sep. 2017

Call for Papers is open – submit your contribution until 10 January 2017

The biannual International Biohydrometallurgy Symposium is the global forum for experts from academia and industry active in the fields of biomining, bioleaching and bioremediation. These technologies have a high potential to establish environmentally favourable processes for the recovery of primary and secondary precious and base metal resources as well as the remediation of exploited mining sites. (Mehr in: Veranstaltungen – idw – Informationsdienst Wissenschaft)

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